Aging Overview

Aging gene

Gene name: BHLHE40
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: MCF-7
Gene ID: 8553
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 18025081
Experiment: SA-β-gal activity assay//Western blot
Description: Microscopic analysis showed that the number of SA-β-galactosidase-positive colonies was increased in DEC1-expressing cells compared with that in control and mutant DEC1-expressing cells.


Regulatory relationship

Target gene: P53
Official symbol(s): P53
R-AG-Target gene: --
Subcategory: Unclear
Target gene experiment: Northern blot
Target gene description: To confirm this, Northern blot analysis was performed. We showed that DEC1 was induced by p53 but not mutant p53(R249S) in H1299 cells.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

Loading,please wait...