Aging Overview

Aging gene

Gene name: HDAC1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: UCB-MSC
Gene ID: 3065
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 20652617
Experiment: SA-β-gal activity assay
Description: Consistently with our previous report, the inhibition of HMGA2 as well as HDAC1 and HDAC2 led to the senescence of hUCB-MSCs as shown by SA β-gal staining, in addition to significantly increased expression of p21CIP1/WAF1 and p16INK4A.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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