| Gene name: | GNG11 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | Fibroblast |
| Experiment: | SA-β-gal activity assay//Cell morphological analysis |
| Description: | We transfected plasmid encoding GNG11 (pG11-sense),they stopped growing 1 week about after transfection, exhibited an enlarged and flat cell shape, and were clearly stained with senescence-associated β-galactosidase. |
| Regulatory pathway: | ERK1/2 |
| R-AG-Pathway: | Activation |
| Official symbol(s): | MAPK3-MAPK1 |
| Pathway experiment: | Western blot |
| Pathway description: | Both ERK1/2 were significantly activated 5 days after transfection, whereas little or no activated forms of p38 and JNK were detected. |
Annotation:
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