Aging Overview

Aging gene

Gene name: CDKN2A
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: DFC
Gene ID: 1029
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 28770470
Experiment: SA-β-Gal activity assay//Western blot
Description: P16 gene silencing reduces the number of senescent cells.Only the protein expression of P16 in DFCs increased successively and significantly while the expression of all other examined cell cycle proteins including that of P21 was down-regulated significantly at higher cell passages.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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