Aging Overview

Aging gene

Gene name: TSHB
Aging type: Prevent
Aging characteristic:
Tissue type: Adipose
Cell name: --
Gene ID: 7252
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 30448824
Experiment: RT-PCR//Telomere length assay
Description: In euthyroid morbidly obese subjects,both SAT and VAT TSHB gene expression was negatively associated with markers of AT senescence (TNF , TP53, BAX and DBC1). Confirming these findings, SAT TSHB mRNA was positively linked to telomere length in a subgroup of consecutive subjects , suggesting decreased senescence with less exposure to thyroid hormones. Furthermore, SAT TSHB mRNA was negatively correlated to specific senescence-associated glucosylceramides.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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