Aging Overview

Aging gene

Gene name: S100A13
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: IMR-90
Gene ID: 6284
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 30670674
Experiment: Knockdown//SA-β-gal activity assay
Description: S100A13 overexpression promotes, whereas S100A13 knockdown delays replicative cellular senescence in IMR9 cells. S100A13 mutant significantly decreased the percentage of SA-β-gal positive staining cells.


Regulatory relationship

Target gene: IL-1
Official symbol(s): IL1B
R-AG-Target gene: Upregulation
Subcategory: Unclear
Target gene experiment: Flow cytometry//Immunoblotting
Target gene description: FACS analysis of cell surface-bound IL-1α showed that S100A13 overexpression significantly enhanced IL-1α levels compared to empty vector control cells.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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