Cancer CRCdb

TF information

TF name:	PRDM1
TF family:	zf-C2H2
Ensembl gene ID:	ENSG00000057657
Ensembl protein ID:	ENSP00000358092, ENSP00000358085, ENSP00000358087
Entrez gene ID:	639

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of PRDM1 in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_182	Cell line	Human melanoma	LOX-IMVI	0.1264367816092
Sample_02_199	Cell line	Stomach	KATO3	0.22222222222222
Sample_02_205	Tissue	Stomach	Gastric_Primary_Sample_T	0.48888888888889

PRDM1 distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name
Sample_02_205	Stomach	Tissue	Gastric_Primary_Sample_T

PRDM1 distribution in all CRCs

Genomic distribution of SEs associated with PRDM1

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Mutation of PRDM1

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of PRDM1

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr6	106547387	106547387	T	C	exonic	PRDM1	synonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
rs779643872	chr6	106553409	106553409	C	T	exonic	PRDM1	synonymous	BLCA\|1\|396\|0.00253
-	chr6	106552790	106552790	A	G	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106547224	106547224	A	G	exonic	PRDM1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr6	106554835	106554835	G	A	exonic	PRDM1	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr6	106536124	106536124	G	A	exonic	PRDM1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr6	106554849	106554849	G	A	exonic	PRDM1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr6	106554844	106554844	C	G	exonic	PRDM1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr6	106552850	106552850	C	T	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106554322	106554322	A	G	exonic	PRDM1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr6	106553637	106553637	C	A	exonic	PRDM1	synonymous	BRCA\|1\|982\|0.00102
-	chr6	106547263	106547263	-	T	exonic	PRDM1	frameshift	THCA\|1\|504\|0.00198
-	chr6	106553602	106553602	G	A	exonic	PRDM1	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr6	106553068	106553068	-	A	exonic	PRDM1	frameshift	LUAD\|4\|543\|0.00737
rs771056895	chr6	106552891	106552891	C	T	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs548489075	chr6	106553183	106553183	C	T	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272,UCEC\|1\|248\|0.00403
rs753864501	chr6	106536322	106536322	G	A	exonic	PRDM1	nonsynonymous	LUSC\|1\|178\|0.00562
rs149556668	chr6	106555109	106555109	C	T	exonic	PRDM1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106553564	106553564	G	A	exonic	PRDM1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr6	106553699	106553699	A	G	exonic	PRDM1	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr6	106553015	106553015	C	G	exonic	PRDM1	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr6	106555118	106555118	G	T	exonic	PRDM1	synonymous	LUSC\|1\|178\|0.00562
-	chr6	106536284	106536284	C	A	exonic	PRDM1	nonsynonymous	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409
-	chr6	106547368	106547368	G	C	exonic	PRDM1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr6	106552875	106552875	C	T	exonic	PRDM1	synonymous	SKCM\|2\|368\|0.00543
-	chr6	106553664	106553664	C	T	exonic	PRDM1	synonymous	BLCA\|1\|396\|0.00253
-	chr6	106554274	106554274	G	A	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106555285	106555285	A	T	exonic	PRDM1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr6	106553037	106553037	T	C	exonic	PRDM1	synonymous	UCEC\|1\|248\|0.00403
-	chr6	106552789	106552789	G	T	exonic	PRDM1	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106553289	106553289	C	G	exonic	PRDM1	stopgain	DLBC\|1\|48\|0.02083
-	chr6	106547271	106547271	G	A	exonic	PRDM1	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr6	106553568	106553568	C	-	exonic	PRDM1	frameshift	LIHC\|1\|373\|0.00268
-	chr6	106536155	106536155	T	C	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106552809	106552809	C	T	exonic	PRDM1	synonymous	SKCM\|1\|368\|0.00272
-	chr6	106555352	106555352	G	T	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs186696135	chr6	106552717	106552717	C	T	exonic	PRDM1	synonymous	HNSC\|1\|512\|0.00195
-	chr6	106553776	106553776	G	A	exonic	PRDM1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr6	106543553	106543553	G	A	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106552934	106552934	C	T	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106547390	106547390	C	G	exonic	PRDM1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr6	106553695	106553695	A	G	exonic	PRDM1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr6	106553106	106553106	G	A	exonic	PRDM1	synonymous	SKCM\|2\|368\|0.00543
-	chr6	106555001	106555001	G	A	exonic	PRDM1	synonymous	CESC\|1\|194\|0.00515
-	chr6	106553486	106553486	C	A	exonic	PRDM1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr6	106543594	106543594	G	A	exonic	PRDM1	synonymous	SKCM\|2\|368\|0.00543
-	chr6	106554840	106554840	C	T	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106547183	106547183	C	T	exonic	PRDM1	synonymous	SKCM\|1\|368\|0.00272
-	chr6	106552814	106552814	C	A	exonic	PRDM1	nonsynonymous	UCS\|1\|57\|0.01754
-	chr6	106555006	106555006	G	A	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
rs774978511	chr6	106553787	106553787	C	T	exonic	PRDM1	synonymous	BRCA\|1\|982\|0.00102,GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr6	106553754	106553754	C	A	exonic	PRDM1	synonymous	UCEC\|1\|248\|0.00403
-	chr6	106536122	106536122	C	T	exonic	PRDM1	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr6	106553082	106553082	C	G	exonic	PRDM1	nonsynonymous	BRCA\|1\|982\|0.00102
rs587778624	chr6	106547211	106547211	G	A	exonic	PRDM1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr6	106555151	106555151	G	A	exonic	PRDM1	synonymous	LUAD\|1\|543\|0.00184
-	chr6	106543577	106543577	C	T	exonic	PRDM1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr6	106553202	106553202	C	T	exonic	PRDM1	synonymous	SKCM\|1\|368\|0.00272
-	chr6	106554799	106554799	G	A	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106553334	106553334	C	T	exonic	PRDM1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106554881	106554881	C	A	exonic	PRDM1	synonymous	LUAD\|1\|543\|0.00184
-	chr6	106543539	106543539	G	A	exonic	PRDM1	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr6	106552829	106552829	A	G	exonic	PRDM1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr6	106553275	106553275	C	T	exonic	PRDM1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr6	106555185	106555185	G	T	exonic	PRDM1	stopgain	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr6	106553132	106553132	G	A	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106536285	106536285	A	G	exonic	PRDM1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106536284	106536284	C	T	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106536292	106536292	C	A	exonic	PRDM1	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr6	106547316	106547316	T	A	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106543518	106543518	T	A	exonic	PRDM1	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr6	106553111	106553111	C	T	exonic	PRDM1	nonsynonymous	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409,UCEC\|1\|248\|0.00403
-	chr6	106554851	106554851	G	A	exonic	PRDM1	synonymous	SKCM\|1\|368\|0.00272
-	chr6	106543515	106543515	A	G	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106554877	106554877	C	T	exonic	PRDM1	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr6	106553064	106553064	C	T	exonic	PRDM1	synonymous	HNSC\|1\|512\|0.00195
-	chr6	106536113	106536113	A	G	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs748874731	chr6	106555018	106555018	C	T	exonic	PRDM1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr6	106553730	106553730	G	A	exonic	PRDM1	synonymous	ESCA\|1\|185\|0.00541
-	chr6	106554286	106554286	G	A	exonic	PRDM1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr6	106553274	106553274	C	T	exonic	PRDM1	synonymous	SKCM\|1\|368\|0.00272
-	chr6	106553291	106553291	G	A	exonic	PRDM1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr6	106552744	106552744	G	A	exonic	PRDM1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr6	106555065	106555065	G	A	exonic	PRDM1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr6	106553302	106553302	A	C	exonic	PRDM1	nonsynonymous	UCS\|1\|57\|0.01754
-	chr6	106553770	106553770	G	A	exonic	PRDM1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr6	106553751	106553751	G	A	exonic	PRDM1	synonymous	SKCM\|1\|368\|0.00272
-	chr6	106553230	106553230	C	T	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106543511	106543511	G	T	exonic	PRDM1	stopgain	UCEC\|1\|248\|0.00403
-	chr6	106554884	106554884	G	A	exonic	PRDM1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106547289	106547289	T	A	exonic	PRDM1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr6	106552868	106552868	A	G	exonic	PRDM1	nonsynonymous	THYM\|1\|123\|0.00813
-	chr6	106554285	106554285	T	C	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106553194	106553194	G	T	exonic	PRDM1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr6	106553119	106553119	C	T	exonic	PRDM1	nonsynonymous	OV\|1\|469\|0.00213
-	chr6	106553418	106553418	C	A	exonic	PRDM1	synonymous	BLCA\|1\|396\|0.00253
-	chr6	106554835	106554835	G	C	exonic	PRDM1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr6	106553643	106553643	A	T	exonic	PRDM1	synonymous	LIHC\|1\|373\|0.00268
-	chr6	106554343	106554343	T	A	exonic	PRDM1	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr6	106553019	106553019	C	T	exonic	PRDM1	synonymous	LIHC\|1\|373\|0.00268
-	chr6	106543608	106543608	G	A	exonic	PRDM1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs747183412	chr6	106553508	106553508	G	A	exonic	PRDM1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs777578275	chr6	106553478	106553478	G	A	exonic	PRDM1	synonymous	ESCA\|1\|185\|0.00541
-	chr6	106552989	106552989	C	T	exonic	PRDM1	synonymous	SKCM\|2\|368\|0.00543
rs774601665	chr6	106553745	106553745	C	T	exonic	PRDM1	synonymous	UCEC\|1\|248\|0.00403
-	chr6	106553658	106553658	C	A	exonic	PRDM1	synonymous	ESCA\|1\|185\|0.00541
-	chr6	106536266	106536266	A	T	exonic	PRDM1	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr6	106552764	106552764	C	T	exonic	PRDM1	synonymous	LIHC\|1\|373\|0.00268
rs765915166	chr6	106553388	106553388	C	T	exonic	PRDM1	synonymous	UCEC\|1\|248\|0.00403
-	chr6	106536323	106536323	A	G	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs867393719	chr6	106553490	106553490	G	A	exonic	PRDM1	synonymous	SKCM\|1\|368\|0.00272
-	chr6	106536080	106536080	C	-	exonic	PRDM1	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106543533	106543533	G	A	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,DLBC\|1\|48\|0.02083
rs143411705	chr6	106555013	106555013	C	T	exonic	PRDM1	synonymous	UCEC\|1\|248\|0.00403
-	chr6	106554794	106554794	C	T	exonic	PRDM1	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr6	106555120	106555120	A	T	exonic	PRDM1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr6	106554352	106554352	G	A	exonic	PRDM1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr6	106553664	106553664	C	A	exonic	PRDM1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr6	106547326	106547326	A	T	exonic	PRDM1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr6	106552891	106552891	-	T	exonic	PRDM1	frameshift	DLBC\|1\|48\|0.02083
rs373718206	chr6	106552731	106552731	C	T	exonic	PRDM1	synonymous	LIHC\|1\|373\|0.00268
-	chr6	106553146	106553146	C	A	exonic	PRDM1	synonymous	UCEC\|1\|248\|0.00403
-	chr6	106555057	106555057	G	A	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
rs367766895	chr6	106552838	106552838	G	A	exonic	PRDM1	nonsynonymous	BLCA\|1\|396\|0.00253,SARC\|1\|247\|0.00405
-	chr6	106552770	106552770	G	-	exonic	PRDM1	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr6	106552789	106552789	G	A	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
rs747743863	chr6	106555167	106555167	G	A	exonic	PRDM1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr6	106552805	106552805	A	G	exonic	PRDM1	nonsynonymous	UCS\|1\|57\|0.01754
rs755699644	chr6	106547367	106547367	C	T	exonic	PRDM1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr6	106553227	106553227	C	T	exonic	PRDM1	nonsynonymous	UCEC\|1\|248\|0.00403
rs528735730	chr6	106554952	106554952	C	T	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106553236	106553236	G	-	exonic	PRDM1	frameshift	HNSC\|1\|512\|0.00195
-	chr6	106553250	106553250	G	A	exonic	PRDM1	synonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125,SKCM\|1\|368\|0.00272
-	chr6	106555270	106555270	A	C	exonic	PRDM1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr6	106547391	106547391	T	C	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106552896	106552896	G	A	exonic	PRDM1	synonymous	BLCA\|2\|396\|0.00505
-	chr6	106555117	106555117	T	C	exonic	PRDM1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr6	106553159	106553159	C	T	exonic	PRDM1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr6	106554875	106554875	C	T	exonic	PRDM1	synonymous	LUAD\|4\|543\|0.00737
rs762241140	chr6	106553539	106553539	G	A	exonic	PRDM1	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr6	106543567	106543567	T	A	exonic	PRDM1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr6	106552701	106552701	A	T	exonic	PRDM1	synonymous	SKCM\|1\|368\|0.00272
-	chr6	106552897	106552897	A	G	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106553306	106553306	G	T	exonic	PRDM1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr6	106555298	106555298	C	T	exonic	PRDM1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr6	106553510	106553510	C	G	exonic	PRDM1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr6	106536269	106536269	C	T	exonic	PRDM1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs375331216	chr6	106536260	106536260	C	T	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr6	106553562	106553562	C	T	exonic	PRDM1	synonymous	SKCM\|1\|368\|0.00272
-	chr6	106555155	106555155	G	A	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106555311	106555311	C	G	exonic	PRDM1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr6	106553555	106553555	A	G	exonic	PRDM1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,UCEC\|1\|248\|0.00403
-	chr6	106553457	106553457	A	-	exonic	PRDM1	frameshift	LUAD\|1\|543\|0.00184
-	chr6	106555230	106555230	G	A	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106547284	106547284	C	A	exonic	PRDM1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr6	106553700	106553700	C	A	exonic	PRDM1	nonsynonymous	CHOL\|1\|35\|0.02857
-	chr6	106553131	106553131	G	T	exonic	PRDM1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr6	106553639	106553639	C	G	exonic	PRDM1	stopgain	BLCA\|2\|396\|0.00505
-	chr6	106546964	106546964	G	A	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106553680	106553680	C	T	exonic	PRDM1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr6	106554333	106554333	C	T	exonic	PRDM1	nonsynonymous	LIHC\|1\|373\|0.00268

Disease information of PRDM1

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
PRDM1	Rheumatoid Arthritis	C05;C17;C20	Disease or Syndrome	CTD_human
PRDM1	Ulcerative Colitis	C06	Disease or Syndrome	CTD_human
PRDM1	Lupus Erythematosus, Systemic	C17;C20	Disease or Syndrome	CTD_human
PRDM1	Diffuse Large B-Cell Lymphoma	C04;C15;C20	Neoplastic Process	CGI
PRDM1	Sicca Syndrome	C05;C07;C11;C17;C20	Disease or Syndrome	CTD_human
PRDM1	Libman-Sacks Disease	C17;C20	Disease or Syndrome	CTD_human
PRDM1	Sjogren's Syndrome	C05;C07;C11;C17;C20	Disease or Syndrome	CTD_human

Pathway associated with PRDM1

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0000824	FOXA1 transcription factor network	pid	45	204
pathway0002301	Transcriptional regulation of pluripotent stem cells	reactome	28	184
pathway0002714	Hs_Nucleotide-binding_Oligomerization_Domain_(NOD)_pathway_WP1433_86035	wikipathways	37	143
pathway0002740	Hs_Endoderm_Differentiation_WP2853_88152	wikipathways	62	260

Go term information of PRDM1

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GO_term_name	GO_term_type	TF_name
GO_CARDIAC_CHAMBER_DEVELOPMENT	BP	PRDM1
GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS	BP	PRDM1
GO_REGULATION_OF_FAT_CELL_DIFFERENTIATION	BP	PRDM1
GO_CORONARY_VASCULATURE_DEVELOPMENT	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION	BP	PRDM1
GO_POSITIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION	BP	PRDM1
GO_WHITE_FAT_CELL_DIFFERENTIATION	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_B_CELL_ACTIVATION	BP	PRDM1
GO_ARTERY_DEVELOPMENT	BP	PRDM1
GO_REGULATION_OF_BROWN_FAT_CELL_DIFFERENTIATION	BP	PRDM1
GO_BLASTOCYST_FORMATION	BP	PRDM1
GO_TONGUE_DEVELOPMENT	BP	PRDM1
GO_PEPTIDYL_ARGININE_MODIFICATION	BP	PRDM1
GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS	BP	PRDM1
GO_AORTA_DEVELOPMENT	BP	PRDM1
GO_CELL_DIFFERENTIATION_INVOLVED_IN_EMBRYONIC_PLACENTA_DEVELOPMENT	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	BP	PRDM1
GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION	BP	PRDM1
GO_EMBRYONIC_PLACENTA_DEVELOPMENT	BP	PRDM1
GO_EYE_PHOTORECEPTOR_CELL_DIFFERENTIATION	BP	PRDM1
GO_PALATE_DEVELOPMENT	BP	PRDM1
GO_REGULATION_OF_GRANULOCYTE_DIFFERENTIATION	BP	PRDM1
GO_ARTERY_MORPHOGENESIS	BP	PRDM1
GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_HEMOPOIESIS	BP	PRDM1
GO_INTESTINAL_EPITHELIAL_CELL_DEVELOPMENT	BP	PRDM1
GO_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	BP	PRDM1
GO_REGULATION_OF_B_CELL_DIFFERENTIATION	BP	PRDM1
GO_REGULATION_OF_DNA_METHYLATION	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION	BP	PRDM1
GO_PHOTORECEPTOR_CELL_DEVELOPMENT	BP	PRDM1
GO_BROWN_FAT_CELL_DIFFERENTIATION	BP	PRDM1
GO_REGULATION_OF_HISTONE_H3_K9_METHYLATION	BP	PRDM1
GO_BLASTOCYST_DEVELOPMENT	BP	PRDM1
GO_CHROMATIN_ORGANIZATION	BP	PRDM1
GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS	BP	PRDM1
GO_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY	BP	PRDM1
GO_MAINTENANCE_OF_CELL_NUMBER	BP	PRDM1
GO_INTESTINAL_EPITHELIAL_CELL_DIFFERENTIATION	BP	PRDM1
GO_CELLULAR_PROCESS_INVOLVED_IN_REPRODUCTION_IN_MULTICELLULAR_ORGANISM	BP	PRDM1
GO_TROPHOBLAST_GIANT_CELL_DIFFERENTIATION	BP	PRDM1
GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DEVELOPMENT	BP	PRDM1
GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION	BP	PRDM1
GO_VENTRICULAR_SEPTUM_DEVELOPMENT	BP	PRDM1
GO_FAT_CELL_DIFFERENTIATION	BP	PRDM1
GO_REGULATION_OF_B_CELL_ACTIVATION	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_B_CELL_PROLIFERATION	BP	PRDM1
GO_REGULATION_OF_CHROMATIN_ORGANIZATION	BP	PRDM1
GO_CELL_FATE_COMMITMENT	BP	PRDM1
GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS	BP	PRDM1
GO_REGULATION_OF_B_CELL_PROLIFERATION	BP	PRDM1
GO_HEART_VALVE_DEVELOPMENT	BP	PRDM1
GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE	BP	PRDM1
GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS_WITHIN_A_TISSUE	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_CELL_ACTIVATION	BP	PRDM1
GO_POSITIVE_REGULATION_OF_B_CELL_DIFFERENTIATION	BP	PRDM1
GO_POSITIVE_REGULATION_OF_HISTONE_METHYLATION	BP	PRDM1
GO_REGULATION_OF_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY	BP	PRDM1
GO_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS	BP	PRDM1
GO_FERTILIZATION	BP	PRDM1
GO_REGULATION_OF_CELLULAR_RESPIRATION	BP	PRDM1
GO_CELL_FATE_SPECIFICATION	BP	PRDM1
GO_EYE_PHOTORECEPTOR_CELL_DEVELOPMENT	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION	BP	PRDM1
GO_MATERNAL_PLACENTA_DEVELOPMENT	BP	PRDM1
GO_MACROMOLECULE_METHYLATION	BP	PRDM1
GO_PEPTIDYL_ARGININE_METHYLATION	BP	PRDM1
GO_PROTEIN_ALKYLATION	BP	PRDM1
GO_EMBRYONIC_ORGAN_DEVELOPMENT	BP	PRDM1
GO_PEPTIDYL_LYSINE_METHYLATION	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER	BP	PRDM1
GO_POST_EMBRYONIC_DEVELOPMENT	BP	PRDM1
GO_NEGATIVE_REGULATION_OF_CELL_COMMUNICATION	BP	PRDM1
GO_EMBRYO_IMPLANTATION	BP	PRDM1
GO_SMAD_BINDING	MF	PRDM1
GO_HISTONE_DEACETYLASE_BINDING	MF	PRDM1
GO_N_METHYLTRANSFERASE_ACTIVITY	MF	PRDM1
GO_PROTEIN_METHYLTRANSFERASE_ACTIVITY	MF	PRDM1
GO_CHROMATIN_DNA_BINDING	MF	PRDM1
GO_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING	MF	PRDM1
GO_HISTONE_LYSINE_N_METHYLTRANSFERASE_ACTIVITY	MF	PRDM1
GO_SEQUENCE_SPECIFIC_DNA_BINDING	MF	PRDM1
GO_LYSINE_N_METHYLTRANSFERASE_ACTIVITY	MF	PRDM1
GO_HISTONE_METHYLTRANSFERASE_ACTIVITY	MF	PRDM1

Survival analysis of PRDM1

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of PRDM1

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)