TF information

TF name: ZFX
TF family: zf-C2H2
Ensembl gene ID: ENSG00000005889
Ensembl protein ID: ENSP00000438233, ENSP00000368486, ENSP00000343384, ENSP00000368475, ENSP00000304985
Entrez gene ID: 7543
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of ZFX in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_007OtherCervicalcervical-cancer_vector0.14569536423841
Sample_02_114Cell lineMammary GlandCAL510.37688442211055

ZFX distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_007CervicalOthercervical-cancer_vector

ZFX distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with ZFX
Download

Mutation of ZFX
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of ZFX

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chrX2419744224197458TATTGAGGACGTTGTTA-exonicZFXframeshift KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chrX2422919224229192GAexonicZFXnonsynonymous BLCA|1|396|0.00253
-chrX2422922124229221GAexonicZFXnonsynonymous UCEC|1|248|0.00403
-chrX2419777724197777ATexonicZFXnonsynonymous LIHC|1|373|0.00268
-chrX2422553124225531CTexonicZFXsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chrX2422909924229099CTexonicZFXnonsynonymous CESC|1|194|0.00515
-chrX2419777124197771CTexonicZFXnonsynonymous BLCA|1|396|0.00253
-chrX2422714024227140CTexonicZFXnonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chrX2422859024228590TCexonicZFXsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chrX2422636024226360TGexonicZFXsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chrX2422596624225966GCexonicZFXnonsynonymous CESC|1|194|0.00515
-chrX2422861024228610A-exonicZFXframeshift COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chrX2422933624229336AGexonicZFXnonsynonymous SKCM|1|368|0.00272
-chrX2422941124229411AGexonicZFXnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chrX2419779124197791GAexonicZFXnonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chrX2422648424226484TCexonicZFXnonsynonymous SKCM|1|368|0.00272
-chrX2422860224228602GAexonicZFXsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chrX2422946424229464CTexonicZFXstopgain DLBC|1|48|0.02083
-chrX2422937824229378CAexonicZFXnonsynonymous LIHC|1|373|0.00268
-chrX2422544124225441ATsplicingZFXsplicing KIPAN|3|799|0.00375,KIRC|3|451|0.00665
-chrX2422591024225910TCexonicZFXnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chrX2422637624226376GAexonicZFXnonsynonymous OV|1|469|0.00213
-chrX2422937824229378CTexonicZFXnonsynonymous SKCM|1|368|0.00272
rs757611052chrX2422716524227165CTexonicZFXsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chrX2419744524197445TCexonicZFXsynonymous KIPAN|2|799|0.00250,KIRC|2|451|0.00443
-chrX2419736724197367AGexonicZFXsynonymous ESCA|1|185|0.00541
-chrX2419751724197517CTexonicZFXsynonymous BLCA|1|396|0.00253
-chrX2419741924197419GAexonicZFXnonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chrX2422634924226349GAexonicZFXnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chrX2419770124197701GAexonicZFXnonsynonymous BRCA|1|982|0.00102
-chrX2422900324229003CTexonicZFXnonsynonymous SKCM|1|368|0.00272
-chrX2419091224190912CTexonicZFXnonsynonymous PAAD|1|185|0.00541
-chrX2422918924229189TCexonicZFXnonsynonymous BLCA|1|396|0.00253
-chrX2422711424227114ACexonicZFXnonsynonymous SARC|1|247|0.00405
-chrX2419752024197520TGexonicZFXnonsynonymous UCEC|1|248|0.00403
-chrX2422843424228434GAexonicZFXsynonymous BRCA|1|982|0.00102
-chrX2422868124228681CTexonicZFXnonsynonymous SKCM|1|368|0.00272
-chrX2422938324229383CGexonicZFXnonsynonymous LUAD|2|543|0.00368
rs746622902chrX2422880024228800GAexonicZFXsynonymous THCA|1|504|0.00198
-chrX2422941024229410GCexonicZFXnonsynonymous BLCA|1|396|0.00253
-chrX2422554924225549-AexonicZFXframeshift SKCM|1|368|0.00272
-chrX2422948824229488CTexonicZFXnonsynonymous PRAD|1|499|0.00200
-chrX2419094924190949CTintronicZFXunknown ESCA|1|185|0.00541
-chrX2422705624227104CAAGTGCCCTCTTGCACATAGATGAGTCTGCTGGCCTCGGCAGACTGGC-exonicZFXframeshift LIHC|1|373|0.00268
-chrX2422877324228773CTexonicZFXsynonymous TGCT|2|155|0.01290
-chrX2419773424197734GAexonicZFXnonsynonymous CESC|1|194|0.00515
-chrX2422888524228885CTexonicZFXnonsynonymous COAD|2|367|0.00545,COADREAD|2|489|0.00409
-chrX2422906224229062ATexonicZFXstopgain SKCM|1|368|0.00272
-chrX2422884224228842TCexonicZFXsynonymous UCEC|1|248|0.00403
-chrX2419090824190908GCexonicZFXnonsynonymous BLCA|1|396|0.00253
-chrX2422913424229134A-exonicZFXframeshift COAD|2|367|0.00545,COADREAD|2|489|0.00409,PAAD|3|185|0.01622,STAD|2|395|0.00506,STES|2|395|0.00506
-chrX2422857824228578GTexonicZFXsynonymous UCEC|1|248|0.00403
-chrX2419777924197779GTexonicZFXnonsynonymous LIHC|1|373|0.00268
-chrX2422935324229353TGexonicZFXnonsynonymous SKCM|1|368|0.00272
-chrX2422877724228777ATexonicZFXstopgain LUAD|1|543|0.00184
rs770714295chrX2422885324228853CTexonicZFXnonsynonymous UCEC|1|248|0.00403
-chrX2422893224228932GTexonicZFXnonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chrX2422637724226377TCexonicZFXnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chrX2422637724226377TAexonicZFXnonsynonymous COAD|2|367|0.00545,COADREAD|2|489|0.00409
rs766815041chrX2422895024228950TCexonicZFXsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chrX2419762824197628GTexonicZFXnonsynonymous LUAD|1|543|0.00184
-chrX2419736624197366CGexonicZFXstopgain BRCA|1|982|0.00102
-chrX2422943824229438CTexonicZFXnonsynonymous SKCM|1|368|0.00272
-chrX2422886624228866TCexonicZFXsynonymous UCEC|1|248|0.00403
-chrX2422943124229431CTexonicZFXstopgain SKCM|1|368|0.00272
rs773999465chrX2422885424228854GAexonicZFXsynonymous HNSC|1|512|0.00195
-chrX2422704324227043CTexonicZFXnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chrX2419747924197479GTexonicZFXnonsynonymous UCEC|1|248|0.00403
-chrX2422635524226355GAexonicZFXnonsynonymous THCA|2|504|0.00397
-chrX2422588824225888GAexonicZFXnonsynonymous UCS|1|57|0.01754
-chrX2422842424228424ACexonicZFXnonsynonymous BRCA|1|982|0.00102
-chrX2422586124225861GCexonicZFXnonsynonymous BRCA|1|982|0.00102
-chrX2419770724197707GAexonicZFXnonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chrX2422866924228669G-exonicZFXframeshift GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chrX2422851224228512GAexonicZFXsynonymous LUAD|1|543|0.00184
-chrX2419784224197842CAexonicZFXnonsynonymous SARC|1|247|0.00405
-chrX2422544824225448GAexonicZFXnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs150173584chrX2422938824229388GAexonicZFXsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs748417793chrX2422943224229432GAexonicZFXnonsynonymous HNSC|1|512|0.00195,SARC|1|247|0.00405,UCEC|2|248|0.00806
-chrX2422588524225885CAexonicZFXnonsynonymous BLCA|1|396|0.00253
-chrX2422926324229263CTexonicZFXstopgain GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chrX2422633524226335AGexonicZFXnonsynonymous COAD|2|367|0.00545,COADREAD|2|489|0.00409,OV|1|469|0.00213
-chrX2422853524228535CTexonicZFXnonsynonymous UCEC|1|248|0.00403
-chrX2422847124228471AGexonicZFXnonsynonymous LUAD|1|543|0.00184
rs758426142chrX2422550324225503CTexonicZFXnonsynonymous CESC|1|194|0.00515
rs372941972chrX2422854524228545CTexonicZFXsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chrX2419776024197760CTexonicZFXsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chrX2422549524225495CTexonicZFXsynonymous PRAD|1|499|0.00200
rs143557208chrX2422881824228818CTexonicZFXsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chrX2422896024228960GTexonicZFXstopgain UCS|1|57|0.01754
-chrX2419782824197828T-exonicZFXframeshift SKCM|1|368|0.00272
-chrX2422559424225594TGsplicingZFXsplicing COADREAD|1|489|0.00204,READ|1|122|0.00820
-chrX2419758424197584GTexonicZFXnonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
rs369124495chrX2422900424229004GAexonicZFXsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,UCEC|1|248|0.00403
-chrX2422847424228474ATexonicZFXstopgain SKCM|1|368|0.00272
-chrX2419761824197618CAexonicZFXstopgain LUSC|1|178|0.00562
-chrX2422889424228894T-exonicZFXframeshift SKCM|1|368|0.00272
-chrX2422915624229156ACexonicZFXnonsynonymous GBM|1|290|0.00345,GBMLGG|1|820|0.00122
-chrX2422910824229109AG-exonicZFXframeshift GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chrX2422709324227093CTexonicZFXsynonymous BLCA|1|396|0.00253,SKCM|1|368|0.00272
-chrX2422945524229455CTexonicZFXnonsynonymous SKCM|1|368|0.00272
-chrX2419754024197540CTexonicZFXnonsynonymous CESC|1|194|0.00515
rs751460995chrX2422897524228975CTexonicZFXstopgain SKCM|2|368|0.00543
-chrX2422555924225559-TexonicZFXframeshift SKCM|1|368|0.00272
-chrX2422840124228401GAexonicZFXsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chrX2419777324197773GAexonicZFXnonsynonymous SKCM|1|368|0.00272
-chrX2422843424228434GTexonicZFXnonsynonymous UCEC|1|248|0.00403
-chrX2419730424197304TCexonicZFXsynonymous SKCM|1|368|0.00272
-chrX2422915024229150-AGAexonicZFXstopgain SKCM|1|368|0.00272
-chrX2422583024225830TGexonicZFXsynonymous BRCA|1|982|0.00102
-chrX2422938724229387CGexonicZFXnonsynonymous SKCM|1|368|0.00272
-chrX2422870324228703GAexonicZFXnonsynonymous UCEC|1|248|0.00403
-chrX2422928124229281ATexonicZFXstopgain SKCM|1|368|0.00272
-chrX2422865424228654GAexonicZFXnonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chrX2419089424190894CAexonicZFXnonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chrX2422936624229366GAexonicZFXnonsynonymous DLBC|1|48|0.02083
-chrX2422880924228809CTexonicZFXsynonymous ESCA|1|185|0.00541,LUAD|2|543|0.00368

Disease information of ZFX
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
ZFX Intellectual Disability C10;C23;F01;F03 Mental or Behavioral Dysfunction GENOMICS_ENGLAND

Pathway associated with ZFX
pathway_ID pathway_name pathway_source gene_number edge_number

Go term information of ZFX
GO_term_name GO_term_type TF_name

Survival analysis of ZFX



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of ZFX