TF information

TF name: USF2
TF family: bHLH
Ensembl gene ID: ENSG00000105698
Ensembl protein ID: ENSP00000368429, ENSP00000471099, ENSP00000222305, ENSP00000470081, ENSP00000471511, ENSP00000340633, ENSP00000469364, ENSP00000471775
Entrez gene ID: 7392
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of USF2 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_183Cell lineSkinSKMEL20.41025641025641
Sample_02_413TissueBrainGBM_24930.016483516483516

USF2 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_183SkinCell lineSKMEL2

USF2 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with USF2
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Mutation of USF2
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of USF2

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr193576199035761990AGexonicUSF2nonsynonymous LUAD|1|543|0.00184
-chr193576964935769649CTexonicUSF2nonsynonymous SKCM|1|368|0.00272
-chr193576149135761491CTexonicUSF2stopgain PRAD|1|499|0.00200
-chr193576140135761401-CAGCGGGGAGGCACGATTTGCCTexonicUSF2frameshift KIPAN|1|799|0.00125,KIRP|1|282|0.00355
-chr193576135235761352TGexonicUSF2synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs775471907chr193576136535761365CTexonicUSF2nonsynonymous SKCM|1|368|0.00272
-chr193576168335761683GTexonicUSF2nonsynonymous LUAD|1|543|0.00184
-chr193576170935761709GAsplicingUSF2splicing UCEC|1|248|0.00403
-chr193576141735761417GTexonicUSF2nonsynonymous LUAD|1|543|0.00184
-chr193576960635769606CGexonicUSF2nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
rs774035837chr193576145635761456CTexonicUSF2nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
rs769279094chr193576168335761683-CexonicUSF2frameshift STAD|1|395|0.00253,STES|1|395|0.00253
-chr193576049535760495CGexonicUSF2nonsynonymous LUAD|1|543|0.00184
-chr193576137535761375AGexonicUSF2nonsynonymous HNSC|2|512|0.00391
-chr193576991235769912CTexonicUSF2nonsynonymous UCEC|1|248|0.00403
-chr193577066035770660A-UTR3USF2unknown ESCA|1|185|0.00541
-chr193576169035761690GAexonicUSF2nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs770157891chr193576057935760579CTexonicUSF2nonsynonymous UCEC|1|248|0.00403
-chr193576960735769607GAexonicUSF2nonsynonymous BLCA|1|396|0.00253
-chr193576962035769620CAexonicUSF2nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr193576143535761435CTexonicUSF2nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr193576986035769860GTexonicUSF2synonymous LUAD|1|543|0.00184
-chr193577040935770409CGUTR3USF2unknown CESC|1|194|0.00515
-chr193576988835769888CTexonicUSF2nonsynonymous UCEC|1|248|0.00403
rs551671278chr193577065935770659A-UTR3USF2unknown ESCA|1|185|0.00541
rs757173577chr193576170835761708CTexonicUSF2nonsynonymous LUAD|1|543|0.00184
-chr193576138435761384GAexonicUSF2nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr193576967935769679ACexonicUSF2nonsynonymous UCEC|1|248|0.00403
rs376281522chr193577009435770094GAexonicUSF2nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs372149835chr193577006535770065GAintronicUSF2unknown BLCA|1|396|0.00253

Disease information of USF2
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source

Pathway associated with USF2
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0002392 Validated transcriptional targets of AP1 family members Fra1 and Fra2 pid 37 165

Go term information of USF2
GO_term_name GO_term_type TF_name
GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS BP USF2
GO_VIRAL_LIFE_CYCLE BP USF2
GO_CELLULAR_RESPONSE_TO_NUTRIENT BP USF2
GO_BODY_FLUID_SECRETION BP USF2
GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_INVOLVED_IN_CELLULAR_RESPONSE_TO_CHEMICAL_STIMULUS BP USF2
GO_RESPONSE_TO_NUTRIENT BP USF2
GO_LACTATION BP USF2
GO_BHLH_TRANSCRIPTION_FACTOR_BINDING MF USF2
GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_BINDING MF USF2

Survival analysis of USF2



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of USF2