Cancer CRCdb

TF information

TF name:	PPARA
TF family:	THR-like
Ensembl gene ID:	ENSG00000186951
Ensembl protein ID:	ENSP00000385523, ENSP00000414752, ENSP00000262735, ENSP00000385246
Entrez gene ID:	5465

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of PPARA in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_354	Cell line	Colon	Colo205	0.12012012012012

PPARA distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name

PPARA distribution in all CRCs

Genomic distribution of SEs associated with PPARA

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Mutation of PPARA

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of PPARA

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr22	46594430	46594430	C	T	exonic	PPARA	synonymous	SKCM\|1\|368\|0.00272
-	chr22	46614215	46614215	G	T	exonic	PPARA	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr22	46611219	46611219	G	T	exonic	PPARA	stopgain	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr22	46628087	46628087	G	A	exonic	PPARA	synonymous	SKCM\|1\|368\|0.00272
-	chr22	46614225	46614225	C	T	exonic	PPARA	synonymous	SKCM\|1\|368\|0.00272
-	chr22	46614186	46614186	C	A	exonic	PPARA	synonymous	UCEC\|1\|248\|0.00403
-	chr22	46611134	46611134	C	T	exonic	PPARA	synonymous	LUSC\|1\|178\|0.00562
-	chr22	46611074	46611074	G	A	exonic	PPARA	synonymous	UCEC\|1\|248\|0.00403
-	chr22	46631032	46631032	C	T	exonic	PPARA	nonsynonymous	CESC\|1\|194\|0.00515,SKCM\|1\|368\|0.00272
rs766483864	chr22	46611088	46611088	C	T	exonic	PPARA	nonsynonymous	SKCM\|2\|368\|0.00543
rs200210427	chr22	46628049	46628049	A	G	exonic	PPARA	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr22	46627756	46627756	C	T	exonic	PPARA	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr22	46628102	46628102	C	A	exonic	PPARA	synonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr22	46594453	46594453	G	C	exonic	PPARA	nonsynonymous	OV\|1\|469\|0.00213
-	chr22	46615714	46615714	C	T	exonic	PPARA	nonsynonymous	SKCM\|2\|368\|0.00543
rs762274909	chr22	46611070	46611070	A	G	exonic	PPARA	nonsynonymous	SARC\|1\|247\|0.00405
-	chr22	46628068	46628068	A	C	exonic	PPARA	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr22	46627934	46627934	C	T	exonic	PPARA	synonymous	UCS\|1\|57\|0.01754
rs1042311	chr22	46627780	46627780	C	T	exonic	PPARA	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr22	46615733	46615733	G	T	exonic	PPARA	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr22	46614253	46614253	T	C	exonic	PPARA	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr22	46611213	46611213	G	T	exonic	PPARA	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr22	46614190	46614190	C	G	exonic	PPARA	nonsynonymous	LIHC\|1\|373\|0.00268
rs749814012	chr22	46611177	46611177	G	A	exonic	PPARA	nonsynonymous	PRAD\|2\|499\|0.00401
-	chr22	46611198	46611198	C	T	exonic	PPARA	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr22	46627709	46627709	G	T	exonic	PPARA	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr22	46627961	46627961	C	T	exonic	PPARA	synonymous	UCEC\|1\|248\|0.00403
-	chr22	46631044	46631044	C	A	exonic	PPARA	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr22	46594329	46594329	G	-	exonic	PPARA	frameshift	LUAD\|1\|543\|0.00184
-	chr22	46594409	46594409	G	T	exonic	PPARA	nonsynonymous	HNSC\|1\|512\|0.00195
rs369963518	chr22	46594478	46594478	G	C	exonic	PPARA	synonymous	SARC\|1\|247\|0.00405
-	chr22	46627995	46627995	A	G	exonic	PPARA	nonsynonymous	ACC\|1\|90\|0.01111
-	chr22	46614165	46614165	C	T	exonic	PPARA	synonymous	SKCM\|1\|368\|0.00272
-	chr22	46628123	46628123	C	A	exonic	PPARA	synonymous	BLCA\|1\|396\|0.00253
-	chr22	46594338	46594338	G	T	exonic	PPARA	stopgain	CHOL\|1\|35\|0.02857
-	chr22	46594404	46594404	G	A	exonic	PPARA	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr22	46627967	46627967	G	T	exonic	PPARA	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr22	46628131	46628131	G	A	exonic	PPARA	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr22	46611143	46611143	C	T	exonic	PPARA	synonymous	LUAD\|1\|543\|0.00184
-	chr22	46628007	46628007	C	T	exonic	PPARA	synonymous	SKCM\|1\|368\|0.00272
rs559996245	chr22	46611129	46611129	G	A	exonic	PPARA	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs779053935	chr22	46614282	46614282	C	T	exonic	PPARA	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs774377701	chr22	46611089	46611089	G	A	exonic	PPARA	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs549236046	chr22	46614182	46614182	G	A	exonic	PPARA	nonsynonymous	HNSC\|1\|512\|0.00195,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs146427416	chr22	46614297	46614297	C	T	exonic	PPARA	synonymous	UCEC\|1\|248\|0.00403
rs371950309	chr22	46627789	46627789	G	A	exonic	PPARA	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs199894775	chr22	46627847	46627847	C	T	exonic	PPARA	synonymous	SKCM\|1\|368\|0.00272,UCEC\|1\|248\|0.00403
rs561580529	chr22	46594486	46594486	C	T	exonic	PPARA	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr22	46627911	46627911	G	A	exonic	PPARA	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr22	46614283	46614283	G	A	exonic	PPARA	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr22	46615854	46615854	C	T	exonic	PPARA	synonymous	SKCM\|2\|368\|0.00543
-	chr22	46627925	46627925	C	T	exonic	PPARA	synonymous	PAAD\|1\|185\|0.00541
-	chr22	46614186	46614186	C	G	exonic	PPARA	synonymous	BLCA\|1\|396\|0.00253
rs747248946	chr22	46631049	46631049	C	T	exonic	PPARA	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs772477466	chr22	46628121	46628121	A	G	exonic	PPARA	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr22	46631062	46631062	-	A	exonic	PPARA	frameshift	LUAD\|1\|543\|0.00184
-	chr22	46615711	46615711	A	C	exonic	PPARA	nonsynonymous	LIHC\|1\|373\|0.00268
rs781580066	chr22	46627935	46627935	A	G	exonic	PPARA	nonsynonymous	THCA\|1\|504\|0.00198
-	chr22	46594462	46594462	C	T	exonic	PPARA	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr22	46614265	46614265	C	T	exonic	PPARA	nonsynonymous	SKCM\|1\|368\|0.00272
rs764930526	chr22	46615723	46615723	C	T	exonic	PPARA	stopgain	UVM\|1\|80\|0.01250
-	chr22	46631236	46631237	CT	-	exonic	PPARA	frameshift	BRCA\|1\|982\|0.00102
-	chr22	46614173	46614173	G	A	exonic	PPARA	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs571736420	chr22	46615710	46615710	G	A	exonic	PPARA	synonymous	LUAD\|1\|543\|0.00184
-	chr22	46615784	46615784	T	-	exonic	PPARA	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs371347006	chr22	46594465	46594465	G	A	exonic	PPARA	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr22	46614298	46614298	G	T	exonic	PPARA	nonsynonymous	ESCA\|1\|185\|0.00541
rs761216470	chr22	46594477	46594477	C	T	exonic	PPARA	nonsynonymous	SKCM\|1\|368\|0.00272
rs774720320	chr22	46627868	46627868	C	T	exonic	PPARA	synonymous	BLCA\|1\|396\|0.00253
-	chr22	46594481	46594481	C	T	exonic	PPARA	synonymous	LIHC\|1\|373\|0.00268
-	chr22	46628055	46628055	G	C	exonic	PPARA	nonsynonymous	SKCM\|1\|368\|0.00272
rs766370613	chr22	46614211	46614211	C	T	exonic	PPARA	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr22	46611192	46611192	G	T	exonic	PPARA	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs751185249	chr22	46628027	46628027	G	A	exonic	PPARA	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr22	46628050	46628050	A	G	exonic	PPARA	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr22	46611162	46611162	G	A	exonic	PPARA	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253

Disease information of PPARA

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
PPARA	Alloxan Diabetes	C18;C19	Experimental Model of Disease	CTD_human
PPARA	Malignant Neoplasms	C04	Neoplastic Process	CTD_human
PPARA	Carcinoma	C04	Neoplastic Process	CTD_human
PPARA	Crohn Disease	C06	Disease or Syndrome	CTD_human
PPARA	Dermatitis, Atopic	C16;C17;C20	Disease or Syndrome	CTD_human
PPARA	Diabetes Mellitus, Experimental	C18;C19	Experimental Model of Disease	CTD_human
PPARA	Diabetes Mellitus, Non-Insulin-Dependent	C18;C19	Disease or Syndrome	CTD_human
PPARA	Drug toxicity	C25	Injury or Poisoning	CTD_human
PPARA	Experimental Autoimmune Encephalomyelitis	C10;C20	Experimental Model of Disease	CTD_human
PPARA	Fatty Liver	C06	Disease or Syndrome	CTD_human
PPARA	Fatty Liver, Alcoholic	C06;C25	Disease or Syndrome	CTD_human
PPARA	Cardiomegaly	C14;C23	Finding	CTD_human
PPARA	Hepatitis, Toxic	C06;C25	Injury or Poisoning	CTD_human
PPARA	Hepatomegaly	C06;C23	Finding	CTD_human
PPARA	Hyperlipidemia	C18	Disease or Syndrome	CTD_human
PPARA	Hyperlipoproteinemias	C18	Disease or Syndrome	CTD_human
PPARA	Hypertensive disease	C14	Disease or Syndrome	CTD_human
PPARA	Hypertriglyceridemia	C18	Disease or Syndrome	CTD_human
PPARA	Hypoglycemia	C18	Disease or Syndrome	CTD_human
PPARA	Inflammation	C23	Pathologic Function	CTD_human
PPARA	Insulin Resistance	C18	Pathologic Function	CTD_human
PPARA	Kidney Diseases	C12;C13	Disease or Syndrome	CTD_human
PPARA	Kidney Failure, Chronic	C12;C13	Disease or Syndrome	CTD_human
PPARA	Acute Kidney Tubular Necrosis	C12;C13	Disease or Syndrome	CTD_human
PPARA	Liver neoplasms	C04;C06	Neoplastic Process	CTD_human
PPARA	Animal Mammary Neoplasms	C04;C22	Neoplastic Process	CTD_human
PPARA	Mammary Neoplasms, Experimental	C04	Experimental Model of Disease; Neoplastic Process	CTD_human
PPARA	Myopathy	C05;C10	Disease or Syndrome	CTD_human
PPARA	Myocardial Reperfusion Injury	C14;C23	Pathologic Function	CTD_human
PPARA	Neoplasms	C04	Neoplastic Process	CTD_human
PPARA	Obesity	C18;C23	Disease or Syndrome	CTD_human
PPARA	Prostatic Neoplasms	C04;C12	Neoplastic Process	CTD_human
PPARA	Proteinuria	C12;C13;C23	Finding	CTD_human
PPARA	Reperfusion Injury	C14;C23	Injury or Poisoning	CTD_human
PPARA	Schizophrenia	F03	Mental or Behavioral Dysfunction	PSYGENET
PPARA	Streptozotocin Diabetes	C18;C19	Experimental Model of Disease	CTD_human
PPARA	Adverse reaction to drug	C25	Pathologic Function	CTD_human
PPARA	Eczema, Infantile	C16;C17;C20	Disease or Syndrome	CTD_human
PPARA	Benign Neoplasm	C04	Neoplastic Process	CTD_human
PPARA	Crohn's disease of large bowel	C06	Disease or Syndrome	CTD_human
PPARA	Anaplastic carcinoma	C04	Neoplastic Process	CTD_human
PPARA	Carcinoma, Spindle-Cell	C04	Neoplastic Process	CTD_human
PPARA	Undifferentiated carcinoma	C04	Neoplastic Process	CTD_human
PPARA	Carcinomatosis	C04	Neoplastic Process	CTD_human
PPARA	Dyslipidemias	C18	Disease or Syndrome	CTD_human
PPARA	Crohn's disease of the ileum	C06	Disease or Syndrome	CTD_human
PPARA	Fasting Hypoglycemia	C18	Disease or Syndrome	CTD_human
PPARA	Reactive hypoglycemia	C18	Disease or Syndrome	CTD_human
PPARA	Malignant neoplasm of liver	C04;C06	Neoplastic Process	CTD_human
PPARA	Malignant neoplasm of prostate	C04;C12	Neoplastic Process	CTD_human
PPARA	Non-alcoholic Fatty Liver Disease	C06	Disease or Syndrome	CTD_human
PPARA	Dyslipoproteinemias	C18	Pathologic Function	CTD_human
PPARA	Regional enteritis	C06	Disease or Syndrome	CTD_human
PPARA	Drug-Induced Liver Disease	C06;C25	Disease or Syndrome	CTD_human
PPARA	Insulin Sensitivity	C18	Pathologic Function	CTD_human
PPARA	IIeocolitis	C06	Disease or Syndrome	CTD_human
PPARA	Mammary Carcinoma, Animal	C04;C22	Neoplastic Process	CTD_human
PPARA	Hepatitis, Drug-Induced	C06;C25	Disease or Syndrome	CTD_human
PPARA	Cardiac Hypertrophy	C14;C23	Pathologic Function	CTD_human
PPARA	Lipidemias	C18	Finding	CTD_human
PPARA	Steatohepatitis	C06	Disease or Syndrome	CTD_human
PPARA	Alcoholic Steatohepatitis	C06;C25	Disease or Syndrome	CTD_human
PPARA	Abdominal obesity metabolic syndrome	C18	Disease or Syndrome	CTD_human
PPARA	Nonalcoholic Steatohepatitis	C06	Disease or Syndrome	CTD_human
PPARA	Drug-Induced Acute Liver Injury	C06;C25	Disease or Syndrome	CTD_human
PPARA	Chemical and Drug Induced Liver Injury	C06;C25	Disease or Syndrome	CTD_human
PPARA	Chemically-Induced Liver Toxicity	C06;C25	Disease or Syndrome	CTD_human

Pathway associated with PPARA

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0000069	Activation of gene expression by SREBF (SREBP)	reactome	42	266
pathway0000316	BMAL1:CLOCK,NPAS2 activates circadian gene expression	reactome	42	282
pathway0000430	Circadian Clock	reactome	49	389
pathway0001534	Nuclear Receptor transcription pathway	reactome	51	284
pathway0001846	Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	reactome	20	122
pathway0001940	RORA activates gene expression	reactome	27	204
pathway0001947	RXR and RAR heterodimerization with other nuclear receptor	pid	26	164
pathway0002299	Transcriptional activation of mitochondrial biogenesis	reactome	43	230
pathway0002460	YAP1- and WWTR1 (TAZ)-stimulated gene expression	reactome	29	144
pathway0002857	Hs_SREBF_and_miR33_in_cholesterol_and_lipid_homeostasis_WP2011_89947	wikipathways	6	12

Go term information of PPARA

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GO_term_name	GO_term_type	TF_name
GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING	BP	PPARA
GO_REGULATION_OF_LIPID_STORAGE	BP	PPARA
GO_SINGLE_ORGANISM_BEHAVIOR	BP	PPARA
GO_CELLULAR_RESPONSE_TO_LIPID	BP	PPARA
GO_CIRCADIAN_REGULATION_OF_GENE_EXPRESSION	BP	PPARA
GO_TOOTH_MINERALIZATION	BP	PPARA
GO_REGULATION_OF_NUCLEOTIDE_CATABOLIC_PROCESS	BP	PPARA
GO_POSITIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS	BP	PPARA
GO_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS	BP	PPARA
GO_WOUND_HEALING	BP	PPARA
GO_REGULATION_OF_SEQUESTERING_OF_TRIGLYCERIDE	BP	PPARA
GO_NEGATIVE_REGULATION_OF_DNA_BINDING	BP	PPARA
GO_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION	BP	PPARA
GO_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS	BP	PPARA
GO_NEGATIVE_REGULATION_OF_PROTEIN_BINDING	BP	PPARA
GO_REGULATION_OF_LIPID_METABOLIC_PROCESS	BP	PPARA
GO_ENAMEL_MINERALIZATION	BP	PPARA
GO_NEGATIVE_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS	BP	PPARA
GO_RESPONSE_TO_ALKALOID	BP	PPARA
GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_FOOD	BP	PPARA
GO_RESPONSE_TO_INSULIN	BP	PPARA
GO_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS	BP	PPARA
GO_REGULATION_OF_RESPONSE_TO_FOOD	BP	PPARA
GO_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS	BP	PPARA
GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS	BP	PPARA
GO_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS	BP	PPARA
GO_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER	BP	PPARA
GO_RESPONSE_TO_NICOTINE	BP	PPARA
GO_NEGATIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS	BP	PPARA
GO_POSITIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS	BP	PPARA
GO_AMELOGENESIS	BP	PPARA
GO_NEGATIVE_REGULATION_OF_BLOOD_PRESSURE	BP	PPARA
GO_NEGATIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION	BP	PPARA
GO_REGULATION_OF_CARBOHYDRATE_BIOSYNTHETIC_PROCESS	BP	PPARA
GO_REGULATION_OF_APPETITE	BP	PPARA
GO_NEGATIVE_REGULATION_OF_LIPID_STORAGE	BP	PPARA
GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY	BP	PPARA
GO_REGULATION_OF_FATTY_ACID_OXIDATION	BP	PPARA
GO_BIOMINERAL_TISSUE_DEVELOPMENT	BP	PPARA
GO_POSITIVE_REGULATION_OF_FATTY_ACID_OXIDATION	BP	PPARA
GO_REGULATION_OF_CHOLESTEROL_STORAGE	BP	PPARA
GO_NEGATIVE_REGULATION_OF_NUCLEOTIDE_CATABOLIC_PROCESS	BP	PPARA
GO_NEGATIVE_REGULATION_OF_COFACTOR_METABOLIC_PROCESS	BP	PPARA
GO_POSITIVE_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS	BP	PPARA
GO_REGULATION_OF_COFACTOR_METABOLIC_PROCESS	BP	PPARA
GO_REGULATION_OF_LIPID_CATABOLIC_PROCESS	BP	PPARA
GO_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER	BP	PPARA
GO_FATTY_ACID_TRANSPORT	BP	PPARA
GO_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING	BP	PPARA
GO_REGULATION_OF_CARBOHYDRATE_CATABOLIC_PROCESS	BP	PPARA
GO_POSITIVE_REGULATION_OF_GLUCONEOGENESIS	BP	PPARA
GO_REGULATION_OF_GLUCONEOGENESIS	BP	PPARA
GO_ODONTOGENESIS	BP	PPARA
GO_NEGATIVE_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS	BP	PPARA
GO_POSITIVE_REGULATION_OF_GLUCOSE_METABOLIC_PROCESS	BP	PPARA
GO_REGULATION_OF_FATTY_ACID_BETA_OXIDATION	BP	PPARA
GO_TRANSCRIPTION_FACTOR_ACTIVITY_DIRECT_LIGAND_REGULATED_SEQUENCE_SPECIFIC_DNA_BINDING	MF	PPARA
GO_STEROID_HORMONE_RECEPTOR_ACTIVITY	MF	PPARA
GO_RNA_POLYMERASE_II_REPRESSING_TRANSCRIPTION_FACTOR_BINDING	MF	PPARA
GO_TRANSCRIPTION_COFACTOR_BINDING	MF	PPARA
GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING	MF	PPARA
GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING	MF	PPARA
GO_DRUG_BINDING	MF	PPARA
GO_UBIQUITIN_LIKE_PROTEIN_CONJUGATING_ENZYME_BINDING	MF	PPARA
GO_TRANSCRIPTION_COACTIVATOR_BINDING	MF	PPARA
GO_REPRESSING_TRANSCRIPTION_FACTOR_BINDING	MF	PPARA
GO_CORE_PROMOTER_PROXIMAL_REGION_DNA_BINDING	MF	PPARA
GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING	MF	PPARA

Survival analysis of PPARA

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of PPARA

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)