TF information

TF name: OLIG2
TF family: bHLH
Ensembl gene ID: ENSG00000205927
Ensembl protein ID: ENSP00000371794, ENSP00000331040
Entrez gene ID: 10215
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of OLIG2 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_250TissueBraintumormodel36910.09375

OLIG2 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name

OLIG2 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with OLIG2
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Mutation of OLIG2
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of OLIG2

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr213439917834399178CTexonicOLIG2nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr213439970134399701CTexonicOLIG2synonymous TGCT|1|155|0.00645
-chr213439935534399355CTexonicOLIG2nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr213439954934399549GAexonicOLIG2nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr213439942434399424CGexonicOLIG2nonsynonymous CESC|1|194|0.00515
-chr213439953234399532TAexonicOLIG2nonsynonymous GBM|1|290|0.00345,GBMLGG|1|820|0.00122
-chr213439940734399407GAexonicOLIG2synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,STAD|1|395|0.00253,STES|1|395|0.00253
rs768519339chr213439943234399432TGexonicOLIG2nonsynonymous BLCA|1|396|0.00253,HNSC|1|512|0.00195,STAD|1|395|0.00253,STES|1|395|0.00253
-chr213439939134399391GAexonicOLIG2nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr213439926734399267GAexonicOLIG2nonsynonymous BLCA|1|396|0.00253
-chr213439932734399327GAexonicOLIG2nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr213439933934399339GAexonicOLIG2nonsynonymous CESC|1|194|0.00515
-chr213439975534399755CAexonicOLIG2synonymous LIHC|1|373|0.00268
-chr213439919434399194GTexonicOLIG2synonymous LUAD|1|543|0.00184
-chr213440011134400111GTexonicOLIG2nonsynonymous LIHC|1|373|0.00268
-chr213439945934399459GAexonicOLIG2nonsynonymous ACC|1|90|0.01111
rs562023180chr213439943734399437GCexonicOLIG2synonymous LUAD|1|543|0.00184
-chr213439931434399314GAexonicOLIG2synonymous STAD|1|395|0.00253,STES|1|395|0.00253

Disease information of OLIG2
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
OLIG2 Psychotic Disorders F03 Mental or Behavioral Dysfunction PSYGENET
OLIG2 Schizophrenia F03 Mental or Behavioral Dysfunction PSYGENET
OLIG2 Nonorganic psychosis Mental or Behavioral Dysfunction PSYGENET

Pathway associated with OLIG2
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0001078 ID netpath 38 213

Go term information of OLIG2
GO_term_name GO_term_type TF_name
GO_POSITIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION BP OLIG2
GO_CELL_DIFFERENTIATION_IN_SPINAL_CORD BP OLIG2
GO_SPINAL_CORD_MOTOR_NEURON_DIFFERENTIATION BP OLIG2
GO_VENTRAL_SPINAL_CORD_DEVELOPMENT BP OLIG2
GO_POSITIVE_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION BP OLIG2
GO_REGULATION_OF_NEURON_DIFFERENTIATION BP OLIG2
GO_GLIOGENESIS BP OLIG2
GO_ENSHEATHMENT_OF_NEURONS BP OLIG2
GO_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION BP OLIG2
GO_DIENCEPHALON_DEVELOPMENT BP OLIG2
GO_CELL_FATE_COMMITMENT BP OLIG2
GO_THALAMUS_DEVELOPMENT BP OLIG2
GO_GLIAL_CELL_FATE_COMMITMENT BP OLIG2
GO_NEURON_FATE_COMMITMENT BP OLIG2
GO_CELL_FATE_SPECIFICATION BP OLIG2
GO_OLIGODENDROCYTE_DIFFERENTIATION BP OLIG2
GO_REGULATION_OF_GLIOGENESIS BP OLIG2
GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION BP OLIG2
GO_POSITIVE_REGULATION_OF_GLIOGENESIS BP OLIG2
GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_BINDING MF OLIG2
GO_HMG_BOX_DOMAIN_BINDING MF OLIG2

Survival analysis of OLIG2



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of OLIG2