Cancer CRCdb

Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_095	Cell line	Mammary Gland	MDA-MB-468	0.024902723735409

Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of IRX6

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr16	55361588	55361588	C	A	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs761554283	chr16	55362885	55362885	C	T	exonic	IRX6	nonsynonymous	UCS\|1\|57\|0.01754
rs139251893	chr16	55361590	55361590	G	A	exonic	IRX6	nonsynonymous	HNSC\|1\|512\|0.00195,PAAD\|1\|185\|0.00541
-	chr16	55361546	55361546	C	T	exonic	IRX6	synonymous	SKCM\|1\|368\|0.00272
-	chr16	55362689	55362689	G	A	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55362955	55362955	G	A	exonic	IRX6	synonymous	PRAD\|1\|499\|0.00200
-	chr16	55361662	55361662	T	A	exonic	IRX6	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr16	55361683	55361683	C	A	exonic	IRX6	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr16	55363090	55363090	C	T	exonic	IRX6	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr16	55363201	55363201	C	A	exonic	IRX6	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr16	55363169	55363169	T	C	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs774494418	chr16	55361692	55361692	G	A	exonic	IRX6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr16	55363007	55363007	C	T	exonic	IRX6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr16	55361536	55361536	A	C	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs762037558	chr16	55363168	55363168	G	A	exonic	IRX6	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs138532658	chr16	55363166	55363166	C	T	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|1\|248\|0.00403
-	chr16	55362757	55362757	G	A	exonic	IRX6	synonymous	PAAD\|1\|185\|0.00541
rs187777953	chr16	55361597	55361597	C	T	exonic	IRX6	synonymous	SKCM\|1\|368\|0.00272
-	chr16	55362962	55362962	G	A	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55360368	55360368	C	T	exonic	IRX6	synonymous	LUAD\|1\|543\|0.00184
-	chr16	55361545	55361545	C	T	exonic	IRX6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr16	55363171	55363171	C	T	exonic	IRX6	synonymous	UCEC\|1\|248\|0.00403
rs758104787	chr16	55363026	55363026	G	A	exonic	IRX6	nonsynonymous	PRAD\|1\|499\|0.00200
rs762901105	chr16	55363057	55363057	C	T	exonic	IRX6	synonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr16	55360271	55360271	C	T	exonic	IRX6	synonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr16	55362678	55362678	A	G	exonic	IRX6	nonsynonymous	UCS\|1\|57\|0.01754
rs748112787	chr16	55360382	55360382	G	A	exonic	IRX6	synonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr16	55362676	55362676	G	A	exonic	IRX6	synonymous	LIHC\|1\|373\|0.00268
-	chr16	55362963	55362963	C	T	exonic	IRX6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr16	55360348	55360348	G	A	exonic	IRX6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr16	55359008	55359008	C	G	exonic	IRX6	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr16	55363085	55363085	G	A	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55362778	55362778	C	T	exonic	IRX6	synonymous	BLCA\|1\|396\|0.00253
-	chr16	55361572	55361572	C	T	exonic	IRX6	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
rs139857215	chr16	55360337	55360337	C	T	exonic	IRX6	synonymous	HNSC\|1\|512\|0.00195
rs757910029	chr16	55361654	55361654	C	T	exonic	IRX6	synonymous	LUAD\|1\|543\|0.00184
-	chr16	55361516	55361516	G	C	exonic	IRX6	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr16	55362858	55362858	G	A	exonic	IRX6	nonsynonymous	BLCA\|2\|396\|0.00505,CESC\|1\|194\|0.00515
-	chr16	55362828	55362828	C	T	exonic	IRX6	nonsynonymous	CESC\|1\|194\|0.00515
-	chr16	55361611	55361611	A	T	exonic	IRX6	nonsynonymous	OV\|1\|469\|0.00213
-	chr16	55361548	55361548	G	-	exonic	IRX6	frameshift	LUSC\|1\|178\|0.00562
-	chr16	55363128	55363128	C	T	exonic	IRX6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr16	55363091	55363091	G	A	exonic	IRX6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr16	55362726	55362726	G	T	exonic	IRX6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr16	55362619	55362619	T	C	exonic	IRX6	synonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs146683202	chr16	55362703	55362703	C	T	exonic	IRX6	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55363164	55363164	C	T	exonic	IRX6	nonsynonymous	STAD\|3\|395\|0.00759,STES\|3\|395\|0.00759
-	chr16	55362814	55362814	G	T	exonic	IRX6	nonsynonymous	TGCT\|1\|155\|0.00645
rs779816494	chr16	55360358	55360358	C	T	exonic	IRX6	synonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr16	55362691	55362691	G	T	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55362936	55362936	C	A	exonic	IRX6	nonsynonymous	ACC\|1\|90\|0.01111
-	chr16	55362701	55362701	G	A	exonic	IRX6	nonsynonymous	SKCM\|1\|368\|0.00272
rs774978136	chr16	55362691	55362691	G	A	exonic	IRX6	synonymous	PRAD\|1\|499\|0.00200
rs562405725	chr16	55362640	55362640	G	T	exonic	IRX6	synonymous	LUAD\|1\|543\|0.00184
rs752482009	chr16	55362636	55362636	G	A	exonic	IRX6	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr16	55362673	55362673	-	AG	exonic	IRX6	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55362966	55362966	C	T	exonic	IRX6	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr16	55362834	55362834	G	A	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55363084	55363084	C	T	exonic	IRX6	synonymous	HNSC\|1\|512\|0.00195
-	chr16	55359021	55359021	T	G	exonic	IRX6	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr16	55362613	55362613	A	C	exonic	IRX6	nonsynonymous	SARC\|1\|247\|0.00405
-	chr16	55361281	55361281	C	T	exonic	IRX6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,PCPG\|1\|184\|0.00543
-	chr16	55360337	55360337	C	G	exonic	IRX6	synonymous	BLCA\|1\|396\|0.00253
-	chr16	55363004	55363004	A	T	exonic	IRX6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr16	55361531	55361531	C	T	exonic	IRX6	synonymous	SKCM\|1\|368\|0.00272
-	chr16	55363131	55363131	A	C	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs768272784	chr16	55359040	55359040	G	A	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55363139	55363139	C	T	exonic	IRX6	synonymous	SKCM\|1\|368\|0.00272,THCA\|1\|504\|0.00198
-	chr16	55360423	55360423	C	T	exonic	IRX6	nonsynonymous	LUAD\|1\|543\|0.00184
rs377555554	chr16	55362807	55362807	G	A	exonic	IRX6	nonsynonymous	PAAD\|1\|185\|0.00541
rs750264638	chr16	55363210	55363210	G	A	exonic	IRX6	synonymous	CESC\|1\|194\|0.00515
rs375761966	chr16	55362903	55362903	G	A	exonic	IRX6	nonsynonymous	BLCA\|1\|396\|0.00253
rs554682141	chr16	55361532	55361532	C	T	exonic	IRX6	stopgain	PAAD\|1\|185\|0.00541
-	chr16	55359008	55359008	C	T	exonic	IRX6	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr16	55362797	55362797	C	T	exonic	IRX6	stopgain	LUAD\|1\|543\|0.00184
-	chr16	55360341	55360341	C	T	exonic	IRX6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr16	55362883	55362883	G	A	exonic	IRX6	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr16	55363122	55363122	G	T	exonic	IRX6	nonsynonymous	PRAD\|1\|499\|0.00200
rs200259402	chr16	55362806	55362806	C	T	exonic	IRX6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,HNSC\|1\|512\|0.00195
-	chr16	55361233	55361233	C	T	exonic	IRX6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr16	55362877	55362877	C	T	exonic	IRX6	synonymous	HNSC\|1\|512\|0.00195
-	chr16	55361611	55361611	A	G	exonic	IRX6	nonsynonymous	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409
-	chr16	55363165	55363165	G	T	exonic	IRX6	synonymous	TGCT\|1\|155\|0.00645
-	chr16	55363013	55363013	A	C	exonic	IRX6	nonsynonymous	ESCA\|1\|185\|0.00541,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55360356	55360356	T	A	exonic	IRX6	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr16	55361260	55361260	C	A	exonic	IRX6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr16	55362791	55362791	G	C	exonic	IRX6	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr16	55361550	55361550	G	T	exonic	IRX6	stopgain	LUSC\|1\|178\|0.00562
-	chr16	55362675	55362676	AG	-	exonic	IRX6	frameshift	BLCA\|2\|396\|0.00505,GBMLGG\|1\|820\|0.00122,HNSC\|1\|512\|0.00195,LGG\|1\|530\|0.00189,LUAD\|1\|543\|0.00184,PAAD\|18\|185\|0.09730,SKCM\|1\|368\|0.00272,THYM\|1\|123\|0.00813
-	chr16	55361564	55361564	A	G	exonic	IRX6	synonymous	PAAD\|1\|185\|0.00541
-	chr16	55362679	55362679	G	A	exonic	IRX6	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr16	55360339	55360339	C	T	exonic	IRX6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr16	55361633	55361633	C	G	exonic	IRX6	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr16	55360397	55360397	C	T	exonic	IRX6	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55360456	55360456	C	T	exonic	IRX6	nonsynonymous	UCEC\|1\|248\|0.00403
rs753210884	chr16	55360397	55360397	C	A	exonic	IRX6	synonymous	LUAD\|1\|543\|0.00184
-	chr16	55361258	55361258	G	T	exonic	IRX6	synonymous	ESCA\|1\|185\|0.00541
-	chr16	55363210	55363210	G	C	exonic	IRX6	synonymous	BLCA\|1\|396\|0.00253
-	chr16	55362886	55362886	G	A	exonic	IRX6	synonymous	CESC\|1\|194\|0.00515
-	chr16	55362738	55362738	C	T	exonic	IRX6	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr16	55362817	55362817	C	T	exonic	IRX6	synonymous	COADREAD\|1\|489\|0.00204,ESCA\|1\|185\|0.00541,READ\|1\|122\|0.00820,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55361675	55361675	C	A	exonic	IRX6	nonsynonymous	LUAD\|4\|543\|0.00737
rs371123518	chr16	55361530	55361530	G	A	exonic	IRX6	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs199714803	chr16	55362625	55362625	C	T	exonic	IRX6	synonymous	DLBC\|1\|48\|0.02083
-	chr16	55362664	55362664	C	G	exonic	IRX6	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr16	55362818	55362818	G	C	exonic	IRX6	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr16	55360430	55360430	G	T	exonic	IRX6	synonymous	ACC\|1\|90\|0.01111
-	chr16	55361271	55361271	G	A	exonic	IRX6	nonsynonymous	SKCM\|1\|368\|0.00272
rs200780673	chr16	55360346	55360346	C	T	exonic	IRX6	synonymous	UCEC\|1\|248\|0.00403
rs769775558	chr16	55360314	55360314	G	A	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	55362679	55362679	G	T	exonic	IRX6	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs146328122	chr16	55361504	55361504	C	T	exonic	IRX6	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|1\|248\|0.00403
rs759942468	chr16	55360387	55360387	C	T	exonic	IRX6	nonsynonymous	HNSC\|1\|512\|0.00195

TF name:	IRX6
TF family:	Homeobox
Ensembl gene ID:	ENSG00000159387
Ensembl protein ID:	ENSP00000290552
Entrez gene ID:	79190

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

TF information

TCGA somatic mutations and clinical variants of IRX6

Survival analysis of IRX6

Expression of IRX6