Cancer CRCdb

Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_095	Cell line	Mammary Gland	MDA-MB-468	0.34630350194553

Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of FOXI1

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr5	169535587	169535587	T	C	exonic	FOXI1	nonsynonymous	SKCM\|2\|368\|0.00543
rs202093484	chr5	169535414	169535414	G	A	exonic	FOXI1	synonymous	UCEC\|1\|248\|0.00403
-	chr5	169535204	169535204	C	A	exonic	FOXI1	nonsynonymous	LIHC\|2\|373\|0.00536
rs763327604	chr5	169535147	169535147	C	T	exonic	FOXI1	synonymous	SKCM\|1\|368\|0.00272
-	chr5	169533034	169533034	C	-	exonic	FOXI1	frameshift	LIHC\|2\|373\|0.00536,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs150705492	chr5	169535566	169535566	G	T	exonic	FOXI1	nonsynonymous	LUAD\|2\|543\|0.00368
rs781004930	chr5	169533040	169533040	G	A	exonic	FOXI1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	169535126	169535126	G	A	exonic	FOXI1	synonymous	SKCM\|1\|368\|0.00272
-	chr5	169533117	169533117	C	T	exonic	FOXI1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	169533358	169533358	G	C	exonic	FOXI1	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr5	169533258	169533258	G	A	exonic	FOXI1	synonymous	LUAD\|1\|543\|0.00184
-	chr5	169533408	169533408	C	G	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	169533358	169533358	G	A	exonic	FOXI1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	169535321	169535321	C	T	exonic	FOXI1	synonymous	SKCM\|1\|368\|0.00272
rs775317199	chr5	169535115	169535115	C	T	exonic	FOXI1	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
rs767090333	chr5	169535349	169535349	G	-	exonic	FOXI1	frameshift	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr5	169535280	169535280	C	T	exonic	FOXI1	nonsynonymous	HNSC\|2\|512\|0.00391
-	chr5	169535095	169535095	T	C	exonic	FOXI1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr5	169533036	169533036	C	T	exonic	FOXI1	synonymous	SKCM\|1\|368\|0.00272
-	chr5	169533307	169533307	G	T	exonic	FOXI1	stopgain	CESC\|1\|194\|0.00515
rs145046338	chr5	169535475	169535475	G	A	exonic	FOXI1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169533520	169533520	G	T	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	169533142	169533142	C	T	exonic	FOXI1	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr5	169533237	169533237	G	A	exonic	FOXI1	synonymous	CESC\|2\|194\|0.01031
-	chr5	169533337	169533337	T	C	exonic	FOXI1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	169533382	169533382	G	A	exonic	FOXI1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169533528	169533528	C	T	exonic	FOXI1	synonymous	UCEC\|1\|248\|0.00403
-	chr5	169535129	169535129	G	A	exonic	FOXI1	synonymous	LUAD\|1\|543\|0.00184
-	chr5	169532981	169532981	C	T	exonic	FOXI1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	169533255	169533255	C	T	exonic	FOXI1	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr5	169535372	169535372	C	A	exonic	FOXI1	synonymous	LIHC\|1\|373\|0.00268
-	chr5	169535450	169535450	G	T	exonic	FOXI1	synonymous	LUSC\|1\|178\|0.00562
-	chr5	169533529	169533529	G	A	exonic	FOXI1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr5	169535378	169535378	C	T	exonic	FOXI1	synonymous	SKCM\|1\|368\|0.00272
-	chr5	169535488	169535488	G	T	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
rs765453562	chr5	169535124	169535124	A	G	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	169533165	169533165	C	A	exonic	FOXI1	synonymous	LUAD\|1\|543\|0.00184
-	chr5	169533504	169533504	C	T	exonic	FOXI1	synonymous	SKCM\|1\|368\|0.00272
-	chr5	169535354	169535354	G	C	exonic	FOXI1	synonymous	LUAD\|1\|543\|0.00184
-	chr5	169535259	169535259	A	G	exonic	FOXI1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	169533078	169533078	G	A	exonic	FOXI1	synonymous	LUAD\|1\|543\|0.00184
rs779571186	chr5	169532974	169532974	G	A	exonic	FOXI1	nonsynonymous	SKCM\|2\|368\|0.00543
rs769427090	chr5	169533417	169533417	C	T	exonic	FOXI1	synonymous	PRAD\|1\|499\|0.00200
-	chr5	169533060	169533060	G	A	exonic	FOXI1	synonymous	SKCM\|2\|368\|0.00543
-	chr5	169535558	169535558	C	A	exonic	FOXI1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs371025378	chr5	169535194	169535194	C	T	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	169535126	169535126	G	C	exonic	FOXI1	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr5	169535247	169535247	C	A	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	169535107	169535107	G	A	exonic	FOXI1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr5	169533422	169533422	C	T	exonic	FOXI1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs56128152	chr5	169535450	169535450	G	A	exonic	FOXI1	synonymous	BRCA\|1\|982\|0.00102
-	chr5	169533089	169533089	G	T	exonic	FOXI1	nonsynonymous	ACC\|1\|90\|0.01111
rs756749477	chr5	169535273	169535273	G	A	exonic	FOXI1	synonymous	LIHC\|1\|373\|0.00268
-	chr5	169535196	169535196	G	T	exonic	FOXI1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr5	169535073	169535073	C	G	exonic	FOXI1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	169532985	169532985	G	A	exonic	FOXI1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs750087966	chr5	169535277	169535277	C	T	exonic	FOXI1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169533524	169533524	A	T	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	169533176	169533176	C	T	exonic	FOXI1	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr5	169533425	169533425	A	G	exonic	FOXI1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs202009815	chr5	169535405	169535405	T	G	exonic	FOXI1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr5	169533097	169533097	C	T	exonic	FOXI1	nonsynonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125,LUAD\|1\|543\|0.00184
rs200309754	chr5	169533534	169533534	G	A	exonic	FOXI1	synonymous	KIPAN\|2\|799\|0.00250,KIRC\|2\|451\|0.00443
-	chr5	169533233	169533233	T	G	exonic	FOXI1	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr5	169533242	169533242	C	T	exonic	FOXI1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169533456	169533456	C	G	exonic	FOXI1	synonymous	SKCM\|1\|368\|0.00272
rs757881412	chr5	169532973	169532973	C	T	exonic	FOXI1	synonymous	SKCM\|2\|368\|0.00543
-	chr5	169533105	169533105	C	T	exonic	FOXI1	synonymous	SKCM\|1\|368\|0.00272
-	chr5	169535193	169535193	C	T	exonic	FOXI1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr5	169535531	169535531	T	A	exonic	FOXI1	synonymous	HNSC\|1\|512\|0.00195
-	chr5	169535068	169535068	G	A	exonic	FOXI1	stopgain	SKCM\|1\|368\|0.00272
rs148265639	chr5	169535349	169535349	G	T	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	169535091	169535091	A	C	exonic	FOXI1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs367809742	chr5	169535491	169535491	C	T	exonic	FOXI1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	169535371	169535371	C	T	exonic	FOXI1	nonsynonymous	SKCM\|1\|368\|0.00272
rs532647880	chr5	169535099	169535099	C	T	exonic	FOXI1	synonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820,SKCM\|1\|368\|0.00272
rs373094576	chr5	169533489	169533489	G	A	exonic	FOXI1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	169535053	169535053	G	A	exonic	FOXI1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	169532985	169532985	G	T	exonic	FOXI1	synonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr5	169535261	169535261	C	A	exonic	FOXI1	synonymous	LUAD\|1\|543\|0.00184
-	chr5	169535226	169535226	G	A	exonic	FOXI1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr5	169533347	169533347	C	T	exonic	FOXI1	nonsynonymous	COAD\|4\|367\|0.01090,COADREAD\|4\|489\|0.00818
-	chr5	169535084	169535084	C	T	exonic	FOXI1	synonymous	BRCA\|1\|982\|0.00102
-	chr5	169533418	169533418	G	A	exonic	FOXI1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs762358509	chr5	169535329	169535329	C	T	exonic	FOXI1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr5	169533452	169533452	A	T	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	169535593	169535593	C	A	exonic	FOXI1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	169533463	169533463	C	T	exonic	FOXI1	stopgain	LUSC\|1\|178\|0.00562
-	chr5	169535540	169535540	C	T	exonic	FOXI1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs377532550	chr5	169535116	169535116	G	A	exonic	FOXI1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr5	169533045	169533045	G	A	exonic	FOXI1	nonsynonymous	SARC\|1\|247\|0.00405,SKCM\|2\|368\|0.00543
-	chr5	169533134	169533134	C	T	exonic	FOXI1	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr5	169535060	169535060	G	T	exonic	FOXI1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169533468	169533468	C	A	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	169535250	169535250	G	-	exonic	FOXI1	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169535162	169535162	C	A	exonic	FOXI1	synonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr5	169535395	169535395	C	A	exonic	FOXI1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr5	169533511	169533511	G	C	exonic	FOXI1	nonsynonymous	SARC\|1\|247\|0.00405
rs773987289	chr5	169533523	169533523	G	A	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
rs761978045	chr5	169533097	169533097	C	A	exonic	FOXI1	synonymous	LUAD\|1\|543\|0.00184
rs775106921	chr5	169533193	169533193	G	A	exonic	FOXI1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169533120	169533120	C	G	exonic	FOXI1	synonymous	LUAD\|4\|543\|0.00737
-	chr5	169533031	169533031	G	C	exonic	FOXI1	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr5	169535244	169535244	T	A	exonic	FOXI1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr5	169535306	169535306	T	G	exonic	FOXI1	synonymous	SKCM\|1\|368\|0.00272
-	chr5	169533111	169533111	G	-	exonic	FOXI1	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr5	169535234	169535234	G	A	exonic	FOXI1	synonymous	SKCM\|1\|368\|0.00272
-	chr5	169535588	169535588	C	T	exonic	FOXI1	synonymous	SKCM\|2\|368\|0.00543
-	chr5	169533492	169533492	C	T	exonic	FOXI1	synonymous	LUSC\|1\|178\|0.00562
-	chr5	169533471	169533471	C	T	exonic	FOXI1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169533520	169533520	G	A	exonic	FOXI1	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr5	169533243	169533243	G	A	exonic	FOXI1	synonymous	PAAD\|1\|185\|0.00541
-	chr5	169532980	169532980	C	T	exonic	FOXI1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169535415	169535415	G	T	exonic	FOXI1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr5	169533060	169533060	G	T	exonic	FOXI1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169535120	169535120	G	A	exonic	FOXI1	synonymous	LUSC\|1\|178\|0.00562,SKCM\|1\|368\|0.00272
-	chr5	169533265	169533265	C	T	exonic	FOXI1	nonsynonymous	PAAD\|1\|185\|0.00541
rs535372917	chr5	169533081	169533081	C	T	exonic	FOXI1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169533005	169533005	G	A	exonic	FOXI1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr5	169533054	169533054	C	A	exonic	FOXI1	stopgain	LUAD\|1\|543\|0.00184

TF name:	FOXI1
TF family:	Fork_head
Ensembl gene ID:	ENSG00000168269
Ensembl protein ID:	ENSP00000415483, ENSP00000304286
Entrez gene ID:	2299

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
FOXI1	Pendred's syndrome	C09;C10;C19;C23	Disease or Syndrome	CTD_human;ORPHANET
FOXI1	Craniofacial Abnormalities	C05;C16	Congenital Abnormality	CTD_human
FOXI1	DEAFNESS, AUTOSOMAL RECESSIVE 4, WITH ENLARGED VESTIBULAR AQUEDUCT	C09;C10;C23	Disease or Syndrome	CTD_human

GO_term_name	GO_term_type	TF_name
GO_ORGAN_MORPHOGENESIS	BP	FOXI1
GO_SENSORY_ORGAN_DEVELOPMENT	BP	FOXI1
GO_SENSORY_ORGAN_MORPHOGENESIS	BP	FOXI1
GO_INNER_EAR_MORPHOGENESIS	BP	FOXI1
GO_DNA_BINDING_BENDING	MF	FOXI1

TF information

TCGA somatic mutations and clinical variants of FOXI1

Survival analysis of FOXI1

Expression of FOXI1