Cancer CRCdb

Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_404	Cell line	Mammary Gland	ZR-75-1_2	0.086330935251799

Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of E4F1

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr16	2284180	2284196	CCGTTCGCCTGCGCGCA	-	exonic	E4F1	frameshift	PAAD\|1\|185\|0.00541
-	chr16	2282892	2282892	A	-	exonic	E4F1	frameshift	UCEC\|1\|248\|0.00403
-	chr16	2282180	2282180	C	A	exonic	E4F1	nonsynonymous	ACC\|2\|90\|0.02222
-	chr16	2282198	2282198	G	A	exonic	E4F1	nonsynonymous	HNSC\|1\|512\|0.00195
rs868100576	chr16	2279661	2279661	G	A	exonic	E4F1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs753628444	chr16	2285069	2285069	C	T	intronic	E4F1	unknown	UCEC\|1\|248\|0.00403
-	chr16	2283133	2283133	C	T	exonic	E4F1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr16	2278450	2278450	C	A	exonic	E4F1	nonsynonymous	UCEC\|1\|248\|0.00403
rs767398028	chr16	2284265	2284265	G	A	exonic	E4F1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs149258624	chr16	2282275	2282275	C	T	exonic	E4F1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr16	2282783	2282783	T	G	exonic	E4F1	nonsynonymous	OV\|1\|469\|0.00213
rs375039813	chr16	2283577	2283577	G	A	exonic	E4F1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs776744880	chr16	2278400	2278400	G	A	exonic	E4F1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2285132	2285132	C	T	exonic	E4F1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr16	2283011	2283011	G	T	splicing	E4F1	splicing	UCEC\|1\|248\|0.00403
-	chr16	2279581	2279581	C	T	exonic	E4F1	nonsynonymous	BLCA\|1\|396\|0.00253
rs200831818	chr16	2273676	2273676	C	A	exonic	E4F1	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr16	2285081	2285081	G	A	splicing	E4F1	splicing	BRCA\|1\|982\|0.00102
-	chr16	2278379	2278379	A	G	exonic	E4F1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2283156	2283156	C	T	exonic	E4F1	nonsynonymous	SKCM\|1\|368\|0.00272
rs199776709	chr16	2283951	2283951	G	A	exonic	E4F1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2283030	2283030	C	T	exonic	E4F1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr16	2273712	2273712	T	C	exonic	E4F1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2285362	2285362	C	-	exonic	E4F1	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2283955	2283955	G	A	exonic	E4F1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr16	2283184	2283184	G	A	exonic	E4F1	synonymous	SKCM\|1\|368\|0.00272
-	chr16	2284690	2284690	G	A	exonic	E4F1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr16	2282857	2282857	C	T	exonic	E4F1	synonymous	SKCM\|1\|368\|0.00272
rs564228065	chr16	2273626	2273626	G	A	exonic	E4F1	synonymous	BLCA\|1\|396\|0.00253
-	chr16	2282831	2282831	T	C	exonic	E4F1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs756118944	chr16	2279622	2279622	G	A	exonic	E4F1	nonsynonymous	PAAD\|1\|185\|0.00541
rs753644907	chr16	2282576	2282576	G	A	exonic	E4F1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2284180	2284180	C	T	exonic	E4F1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr16	2282276	2282276	G	T	exonic	E4F1	nonsynonymous	LUAD\|1\|543\|0.00184
rs144383218	chr16	2282496	2282496	C	T	exonic	E4F1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr16	2282530	2282530	C	T	exonic	E4F1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr16	2282320	2282320	G	T	exonic	E4F1	nonsynonymous	UCEC\|1\|248\|0.00403
rs779587447	chr16	2285285	2285285	C	T	exonic	E4F1	synonymous	SKCM\|1\|368\|0.00272,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2273689	2273689	G	A	exonic	E4F1	synonymous	HNSC\|1\|512\|0.00195
rs780354367	chr16	2284933	2284933	G	A	exonic	E4F1	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,SARC\|1\|247\|0.00405
-	chr16	2285496	2285496	G	A	exonic	E4F1	nonsynonymous	LUAD\|1\|543\|0.00184,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2285495	2285495	C	-	exonic	E4F1	frameshift	BLCA\|1\|396\|0.00253
-	chr16	2282359	2282359	C	G	exonic	E4F1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr16	2283540	2283540	-	G	exonic	E4F1	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr16	2283182	2283182	G	T	exonic	E4F1	stopgain	HNSC\|1\|512\|0.00195
-	chr16	2284279	2284279	G	A	exonic	E4F1	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr16	2282575	2282575	C	T	exonic	E4F1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr16	2279638	2279638	C	T	exonic	E4F1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr16	2283116	2283116	A	G	exonic	E4F1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr16	2278460	2278460	G	T	exonic	E4F1	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr16	2278405	2278405	C	G	exonic	E4F1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr16	2284592	2284592	G	A	exonic	E4F1	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr16	2282184	2282184	T	C	exonic	E4F1	nonsynonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr16	2285351	2285351	C	T	exonic	E4F1	synonymous	BLCA\|2\|396\|0.00505
-	chr16	2284352	2284352	A	G	exonic	E4F1	nonsynonymous	ACC\|1\|90\|0.01111
rs543875333	chr16	2282899	2282899	C	T	exonic	E4F1	synonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr16	2284179	2284179	G	A	exonic	E4F1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2283890	2283890	C	T	exonic	E4F1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr16	2285002	2285002	G	T	exonic	E4F1	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr16	2282783	2282783	T	C	exonic	E4F1	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr16	2283533	2283533	G	C	exonic	E4F1	nonsynonymous	CESC\|1\|194\|0.00515
-	chr16	2284863	2284863	G	A	exonic	E4F1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs770711229	chr16	2284258	2284258	G	A	exonic	E4F1	nonsynonymous	SKCM\|1\|368\|0.00272
rs761050026	chr16	2283533	2283533	G	A	exonic	E4F1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,THCA\|1\|504\|0.00198
-	chr16	2282755	2282755	A	C	splicing	E4F1	splicing	LIHC\|1\|373\|0.00268
-	chr16	2282537	2282537	C	T	exonic	E4F1	synonymous	UCS\|1\|57\|0.01754
-	chr16	2284322	2284322	A	T	exonic	E4F1	nonsynonymous	LUAD\|1\|543\|0.00184
rs142977286	chr16	2284270	2284270	C	T	exonic	E4F1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs751937000	chr16	2282237	2282237	G	A	exonic	E4F1	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr16	2273707	2273707	G	A	exonic	E4F1	synonymous	HNSC\|1\|512\|0.00195
-	chr16	2279640	2279640	C	T	exonic	E4F1	synonymous	BLCA\|1\|396\|0.00253
rs142410368	chr16	2285268	2285268	G	A	exonic	E4F1	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs113270919	chr16	2284185	2284185	C	T	exonic	E4F1	synonymous	SKCM\|1\|368\|0.00272
-	chr16	2284337	2284337	C	T	exonic	E4F1	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr16	2283125	2283125	C	T	exonic	E4F1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr16	2282838	2282838	C	T	exonic	E4F1	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr16	2284682	2284682	G	A	exonic	E4F1	synonymous	TGCT\|1\|155\|0.00645
-	chr16	2285348	2285348	C	T	exonic	E4F1	synonymous	LUAD\|1\|543\|0.00184
rs149258624	chr16	2282275	2282275	C	G	exonic	E4F1	synonymous	LUSC\|1\|178\|0.00562
rs774106146	chr16	2284316	2284316	G	A	exonic	E4F1	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr16	2278471	2278471	C	T	exonic	E4F1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr16	2284977	2284977	C	A	exonic	E4F1	nonsynonymous	BLCA\|1\|396\|0.00253
rs770063253	chr16	2282763	2282763	G	A	exonic	E4F1	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2284613	2284613	C	T	exonic	E4F1	synonymous	PRAD\|1\|499\|0.00200
rs542965861	chr16	2285568	2285568	G	A	exonic	E4F1	nonsynonymous	CESC\|1\|194\|0.00515,SKCM\|1\|368\|0.00272
-	chr16	2279574	2279574	G	T	exonic	E4F1	nonsynonymous	TGCT\|1\|155\|0.00645
-	chr16	2285119	2285119	A	G	exonic	E4F1	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs529907238	chr16	2285271	2285271	G	A	exonic	E4F1	nonsynonymous	HNSC\|1\|512\|0.00195
rs549051976	chr16	2284966	2284966	G	A	exonic	E4F1	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs752283262	chr16	2285339	2285339	C	T	exonic	E4F1	synonymous	UCEC\|1\|248\|0.00403
-	chr16	2285489	2285489	G	T	exonic	E4F1	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr16	2284186	2284186	G	C	exonic	E4F1	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr16	2285460	2285460	C	T	exonic	E4F1	stopgain	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr16	2282221	2282221	A	G	exonic	E4F1	synonymous	BRCA\|1\|982\|0.00102
-	chr16	2279622	2279622	G	C	exonic	E4F1	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr16	2284212	2284212	C	T	exonic	E4F1	synonymous	UCEC\|1\|248\|0.00403

TF name:	E4F1
TF family:	zf-C2H2
Ensembl gene ID:	ENSG00000167967
Ensembl protein ID:	ENSP00000301727, ENSP00000457672, ENSP00000454652, ENSP00000456760
Entrez gene ID:	1877

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

GO_term_name	GO_term_type	TF_name
GO_CELL_CYCLE_ARREST	BP	E4F1
GO_MITOTIC_CELL_CYCLE_ARREST	BP	E4F1
GO_NEGATIVE_REGULATION_OF_CELL_CYCLE	BP	E4F1
GO_CAMP_RESPONSE_ELEMENT_BINDING	MF	E4F1

TF information

TCGA somatic mutations and clinical variants of E4F1

Survival analysis of E4F1

Expression of E4F1