Cancer CRCdb

Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_268	Cell line	Kidney	A-498	0.020675650729186
Sample_02_430	Cell line	Kidney	12364284	0.32142857142857

Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of CREB5

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr7	28452443	28452443	G	A	UTR5	CREB5	unknown	SKCM\|1\|368\|0.00272
-	chr7	28844035	28844035	C	T	exonic	CREB5	stopgain	CESC\|1\|194\|0.00515
-	chr7	28610075	28610075	C	A	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	28527810	28527810	G	T	exonic	CREB5	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	28534607	28534607	T	A	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	28858791	28858791	C	T	exonic	CREB5	synonymous	UCEC\|1\|248\|0.00403
-	chr7	28857758	28857758	C	T	exonic	CREB5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	28547306	28547306	C	T	exonic	CREB5	nonsynonymous	SKCM\|2\|368\|0.00543
-	chr7	28527851	28527851	C	T	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
rs142741982	chr7	28547354	28547354	G	A	exonic	CREB5	nonsynonymous	TGCT\|1\|155\|0.00645
-	chr7	28848855	28848855	C	T	exonic	CREB5	stopgain	LUAD\|4\|543\|0.00737
-	chr7	28547289	28547289	C	T	exonic	CREB5	synonymous	UCS\|1\|57\|0.01754
-	chr7	28610012	28610012	G	T	exonic	CREB5	synonymous	ACC\|1\|90\|0.01111
-	chr7	28848848	28848848	G	A	exonic	CREB5	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	28848987	28848987	G	T	exonic	CREB5	stopgain	LUAD\|1\|543\|0.00184
rs573375434	chr7	28843920	28843920	G	A	exonic	CREB5	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs150680376	chr7	28758481	28758481	C	T	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
-	chr7	28843947	28843947	G	T	exonic	CREB5	synonymous	LIHC\|1\|373\|0.00268
-	chr7	28547272	28547272	G	A	exonic	CREB5	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	28843972	28843972	C	A	exonic	CREB5	nonsynonymous	CESC\|1\|194\|0.00515
-	chr7	28534602	28534602	G	C	exonic	CREB5	nonsynonymous	BLCA\|1\|396\|0.00253
rs765698094	chr7	28547244	28547244	G	A	exonic	CREB5	synonymous	BRCA\|1\|982\|0.00102
-	chr7	28610009	28610009	T	G	exonic	CREB5	synonymous	BRCA\|1\|982\|0.00102
-	chr7	28857793	28857793	C	T	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
-	chr7	28610060	28610060	C	T	exonic	CREB5	synonymous	BLCA\|1\|396\|0.00253
-	chr7	28849029	28849029	C	-	exonic	CREB5	frameshift	LUAD\|1\|543\|0.00184
-	chr7	28610010	28610010	G	T	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
rs377293245	chr7	28843904	28843904	C	T	exonic	CREB5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	28844058	28844058	C	A	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	28844069	28844069	A	C	exonic	CREB5	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	28858876	28858876	G	T	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	28610004	28610004	G	A	exonic	CREB5	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	28534558	28534558	G	A	exonic	CREB5	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	28848987	28848987	G	C	exonic	CREB5	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs760077074	chr7	28547243	28547243	C	T	exonic	CREB5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	28547322	28547322	C	T	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
rs766189534	chr7	28547353	28547353	C	T	exonic	CREB5	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	28857757	28857757	C	A	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	28858795	28858795	C	A	exonic	CREB5	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	28858777	28858777	C	T	exonic	CREB5	stopgain	BLCA\|1\|396\|0.00253
-	chr7	28857730	28857730	C	T	exonic	CREB5	stopgain	UCEC\|1\|248\|0.00403
-	chr7	28857687	28857687	G	C	splicing	CREB5	splicing	HNSC\|1\|512\|0.00195
-	chr7	28848891	28848891	G	A	exonic	CREB5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	28857705	28857705	G	A	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
-	chr7	28725799	28725799	C	A	exonic	CREB5	stopgain	BLCA\|1\|396\|0.00253
-	chr7	28848933	28848933	C	T	exonic	CREB5	nonsynonymous	CESC\|1\|194\|0.00515
rs767456309	chr7	28547253	28547253	G	A	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
-	chr7	28857725	28857725	T	A	exonic	CREB5	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	28547242	28547242	C	T	exonic	CREB5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	28844033	28844033	A	C	exonic	CREB5	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	28610069	28610069	C	T	exonic	CREB5	synonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr7	28843965	28843965	G	A	exonic	CREB5	synonymous	LUAD\|1\|543\|0.00184
-	chr7	28857755	28857755	G	T	exonic	CREB5	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	28534587	28534587	C	T	exonic	CREB5	nonsynonymous	SKCM\|2\|368\|0.00543
rs762102181	chr7	28547252	28547252	C	T	exonic	CREB5	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr7	28610110	28610110	C	A	exonic	CREB5	nonsynonymous	PAAD\|1\|185\|0.00541
rs748953026	chr7	28763860	28763860	A	G	exonic	CREB5	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	28843913	28843913	A	C	exonic	CREB5	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	28848986	28848986	G	A	exonic	CREB5	synonymous	BLCA\|1\|396\|0.00253
-	chr7	28844023	28844023	C	G	exonic	CREB5	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	28858853	28858853	G	T	exonic	CREB5	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	28610085	28610085	C	T	exonic	CREB5	stopgain	LUAD\|1\|543\|0.00184
-	chr7	28848934	28848934	G	C	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	28763907	28763907	T	A	exonic	CREB5	stopgain	BLCA\|1\|396\|0.00253
rs555693522	chr7	28610098	28610098	C	T	exonic	CREB5	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	28610022	28610022	G	A	exonic	CREB5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	28843891	28843891	G	A	exonic	CREB5	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	28848864	28848864	G	-	exonic	CREB5	frameshift	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr7	28547262	28547262	G	A	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
-	chr7	28610045	28610045	C	A	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	28848894	28848894	G	A	exonic	CREB5	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr7	28848877	28848877	G	A	exonic	CREB5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	28527850	28527850	C	A	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	28848876	28848876	C	G	exonic	CREB5	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	28763871	28763871	C	T	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
-	chr7	28547355	28547355	G	T	exonic	CREB5	synonymous	BRCA\|1\|982\|0.00102
-	chr7	28843966	28843966	C	T	exonic	CREB5	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr7	28610108	28610108	G	A	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
-	chr7	28534554	28534554	C	T	exonic	CREB5	nonsynonymous	CESC\|1\|194\|0.00515
rs61736232	chr7	28844112	28844112	G	A	exonic	CREB5	synonymous	PAAD\|1\|185\|0.00541,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs370060119	chr7	28858886	28858886	C	T	exonic	CREB5	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	28858881	28858881	G	A	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
-	chr7	28848907	28848907	G	A	exonic	CREB5	nonsynonymous	LUSC\|1\|178\|0.00562
rs369220982	chr7	28844124	28844124	C	T	exonic	CREB5	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	28858731	28858731	A	G	splicing	CREB5	splicing	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	28848929	28848929	G	A	exonic	CREB5	synonymous	LUAD\|1\|543\|0.00184
-	chr7	28534529	28534529	C	T	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
-	chr7	28725814	28725814	G	T	exonic	CREB5	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	28610146	28610146	G	T	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
rs761100378	chr7	28610052	28610052	C	T	exonic	CREB5	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	28848898	28848898	C	T	exonic	CREB5	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,LUAD\|1\|543\|0.00184
-	chr7	28610119	28610119	T	A	exonic	CREB5	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	28547292	28547292	C	A	exonic	CREB5	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr7	28534569	28534569	G	A	exonic	CREB5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	28858738	28858738	G	T	exonic	CREB5	stopgain	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	28450121	28450121	G	A	intronic	CREB5	unknown	ESCA\|1\|185\|0.00541
-	chr7	28527820	28527820	G	A	exonic	CREB5	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	28610154	28610154	G	C	exonic	CREB5	nonsynonymous	UCS\|1\|57\|0.01754
rs751547946	chr7	28848902	28848902	C	T	exonic	CREB5	synonymous	SKCM\|1\|368\|0.00272
-	chr7	28610044	28610044	G	T	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	28848967	28848967	A	G	exonic	CREB5	nonsynonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
-	chr7	28848871	28848871	G	A	exonic	CREB5	nonsynonymous	HNSC\|1\|512\|0.00195
rs537303404	chr7	28610021	28610021	G	A	exonic	CREB5	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs747555411	chr7	28547316	28547316	C	T	exonic	CREB5	synonymous	UCEC\|1\|248\|0.00403
rs557766445	chr7	28610048	28610048	C	T	exonic	CREB5	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	28857735	28857735	G	A	exonic	CREB5	synonymous	LUSC\|1\|178\|0.00562
-	chr7	28547236	28547236	C	G	exonic	CREB5	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	28844011	28844011	C	T	exonic	CREB5	nonsynonymous	HNSC\|2\|512\|0.00391
-	chr7	28857752	28857752	A	G	exonic	CREB5	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	28610022	28610022	G	T	exonic	CREB5	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr7	28843821	28843821	G	A	exonic	CREB5	synonymous	BLCA\|1\|396\|0.00253
rs748456667	chr7	28858814	28858814	C	T	exonic	CREB5	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	28843925	28843925	A	G	exonic	CREB5	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs565546192	chr7	28843919	28843919	C	T	exonic	CREB5	nonsynonymous	CESC\|1\|194\|0.00515
rs756899888	chr7	28609991	28609991	G	A	exonic	CREB5	synonymous	HNSC\|1\|512\|0.00195,SKCM\|1\|368\|0.00272
-	chr7	28858828	28858828	G	T	exonic	CREB5	stopgain	BLCA\|1\|396\|0.00253
-	chr7	28547292	28547292	C	T	exonic	CREB5	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	28527826	28527826	G	C	exonic	CREB5	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	28857695	28857695	T	G	exonic	CREB5	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	28534608	28534608	A	T	exonic	CREB5	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	28858838	28858838	G	A	exonic	CREB5	nonsynonymous	BLCA\|1\|396\|0.00253
rs376502932	chr7	28848874	28848874	G	A	exonic	CREB5	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	28527795	28527795	T	C	exonic	CREB5	synonymous	PRAD\|1\|499\|0.00200
-	chr7	28844106	28844106	A	T	exonic	CREB5	synonymous	LUSC\|1\|178\|0.00562
-	chr7	28848830	28848830	G	A	exonic	CREB5	synonymous	BRCA\|1\|982\|0.00102
-	chr7	28857778	28857778	G	T	exonic	CREB5	stopgain	UCEC\|1\|248\|0.00403

TF name:	CREB5
TF family:	TF_bZIP
Ensembl gene ID:	ENSG00000146592
Ensembl protein ID:	ENSP00000379593, ENSP00000387197, ENSP00000379592, ENSP00000350359, ENSP00000379594
Entrez gene ID:	9586

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0001005	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway	panther	126	1529
pathway0002297	Transcription regulation by bZIP transcription factor	panther	42	653
pathway0002633	Vasopressin-regulated water reabsorption	kegg	35	126
pathway0002662	Prostate cancer	kegg	85	1261
pathway0002818	Hs_MFAP5-mediated_ovarian_cancer_cell_motility_and_invasiveness_WP3301_87836	wikipathways	5	11

TF information

TCGA somatic mutations and clinical variants of CREB5

Survival analysis of CREB5

Expression of CREB5