TF information

TF name: ATF1
TF family: TF_bZIP
Ensembl gene ID: ENSG00000123268
Ensembl protein ID: ENSP00000262053
Entrez gene ID: 466
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of ATF1 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_237Cell lineColonV3890.29195656175225
Sample_02_242Cell lineColonV4810.38521438184964

ATF1 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_242ColonCell lineV481

ATF1 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with ATF1
Download

Mutation of ATF1
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of ATF1

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr125120807451208074GAexonicATF1nonsynonymous SKCM|1|368|0.00272
-chr125121342851213428CGexonicATF1nonsynonymous OV|1|469|0.00213
-chr125121343051213430ATexonicATF1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125120821151208211ATexonicATF1nonsynonymous SKCM|1|368|0.00272
-chr125120328951203289ATexonicATF1nonsynonymous LUAD|1|543|0.00184
-chr125120323851203238GTsplicingATF1splicing UCEC|1|248|0.00403
-chr125121350251213502TGexonicATF1nonsynonymous KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr125121352951213529TGexonicATF1synonymous UCEC|1|248|0.00403
-chr125118972851189728TGexonicATF1nonsynonymous UCEC|1|248|0.00403
-chr125121342851213428CTexonicATF1stopgain COAD|3|367|0.00817,COADREAD|3|489|0.00613
-chr125120783451207834GAexonicATF1nonsynonymous BLCA|1|396|0.00253
-chr125117395451173954CTexonicATF1nonsynonymous HNSC|1|512|0.00195
-chr125121344451213445AG-exonicATF1frameshift GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr125120325551203255TCexonicATF1synonymous COAD|3|367|0.00817,COADREAD|3|489|0.00613
-chr125120779651207796CTexonicATF1nonsynonymous UCEC|1|248|0.00403
-chr125120809151208091GCexonicATF1nonsynonymous BRCA|1|982|0.00102
-chr125120780451207804CTexonicATF1nonsynonymous SKCM|1|368|0.00272
rs763994606chr125117399351173993GAexonicATF1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,SKCM|1|368|0.00272
rs781155610chr125120788951207889CTexonicATF1nonsynonymous BRCA|1|982|0.00102
-chr125121342851213428CAexonicATF1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125121343051213430AGexonicATF1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125118972451189724GTexonicATF1nonsynonymous UCEC|1|248|0.00403
rs146231358chr125118973351189733CTexonicATF1synonymous UCEC|1|248|0.00403
-chr125120809151208091GAexonicATF1synonymous BLCA|1|396|0.00253
-chr125117396151173961GCexonicATF1nonsynonymous HNSC|1|512|0.00195
-chr125117401651174016CAexonicATF1nonsynonymous COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr125120325551203255TAexonicATF1nonsynonymous OV|1|469|0.00213
-chr125121342951213429GTexonicATF1nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125120780551207805CTexonicATF1nonsynonymous SKCM|1|368|0.00272
-chr125121353951213539CTexonicATF1nonsynonymous SKCM|1|368|0.00272
-chr125120819851208198GCexonicATF1nonsynonymous UCEC|1|248|0.00403
-chr125120780251207802CTexonicATF1nonsynonymous UCEC|1|248|0.00403
-chr125120788751207887TCexonicATF1synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr125120783051207830TCexonicATF1synonymous ACC|1|90|0.01111
-chr125121351551213515G-exonicATF1frameshift KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr125120332051203320CTexonicATF1synonymous HNSC|1|512|0.00195
-chr125120331651203316CAexonicATF1nonsynonymous PAAD|1|185|0.00541
-chr125120789151207891CTexonicATF1stopgain BLCA|1|396|0.00253
-chr125121345351213453AGexonicATF1nonsynonymous HNSC|1|512|0.00195
rs549207784chr125120329051203290CTexonicATF1synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr125121346151213461ACexonicATF1nonsynonymous PCPG|1|184|0.00543
-chr125120334951203349AGexonicATF1nonsynonymous BRCA|1|982|0.00102

Disease information of ATF1
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
ATF1 Polycystic Ovary Syndrome C04;C13;C19 Disease or Syndrome CTD_human
ATF1 Clear Cell Sarcoma of Soft Tissue C04 Neoplastic Process ORPHANET
ATF1 Sclerocystic Ovaries C04;C13;C19 Disease or Syndrome CTD_human

Pathway associated with ATF1
pathway_ID pathway_name pathway_source gene_number edge_number
pathway0000501 CREB phosphorylation reactome 7 11
pathway0000692 ErbB1 downstream signaling pid 105 1597
pathway0001126 IL3 netpath 84 1284
pathway0001264 Leptin netpath 98 1355
pathway0002044 Signaling mediated by p38-alpha and p38-beta pid 35 174
pathway0002750 Hs_Serotonin_Receptor_4-6-7_and_NR3C_Signaling_WP734_74438 wikipathways 15 37
pathway0002751 Hs_Integrated_Cancer_Pathway_WP1971_82939 wikipathways 33 206

Go term information of ATF1
GO_term_name GO_term_type TF_name
GO_POSITIVE_REGULATION_OF_DNA_METABOLIC_PROCESS BP ATF1
GO_RESPONSE_TO_COBALT_ION BP ATF1
GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION BP ATF1
GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_COMPLEX CC ATF1
GO_PROTEIN_HETERODIMERIZATION_ACTIVITY MF ATF1

Survival analysis of ATF1



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of ATF1