About Enhancer
| Enhancer ID: |
E_02_0369 |
| Species: |
human |
| Position :
|
chr7:55016526-55018526
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Lung cancer |
| Pubmed ID: |
32561533
|
| Enhancer experiment: |
qPCR?Immunoprecipitation?Western blotting? immunohistochemical?Flow cytometry |
| Enhancer experiment description: |
Endocan facilitated EGFR signaling via direct 12 binding and enhancing of the EGF-EGFR interaction and supported the growth of 13 tumors driven by mutated EGFR. |
About Target gene
| Target gene : |
EGFR |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Endocan facilitated EGFR signaling via direct 12 binding and enhancing of the EGF-EGFR interaction and supported the growth of 13 tumors driven by mutated EGFR. |
About TF
| TF name : |
-- |
| TF experiment: |
qPCR?Immunoprecipitation?Western blotting? immunohistochemical?Flow cytometry |
| TF experiment description: |
Endocan facilitated EGFR signaling via direct 12 binding and enhancing of the EGF-EGFR interaction and supported the growth of 13 tumors driven by mutated EGFR. |
About Function
| Enhancer function : |
Endocan facilitated EGFR signaling via direct 12 binding and enhancing of the EGF-EGFR interaction and supported the growth of 13 tumors driven by mutated EGFR. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Endocan facilitated EGFR signaling via direct 12 binding and enhancing of the EGF-EGFR interaction and supported the growth of 13 tumors driven by mutated EGFR. |
About SNP
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs