About Enhancer
| Enhancer ID: |
E_02_0080 |
| Species: |
human |
| Position :
|
chr13:73052423-73054423
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
-- |
| Pubmed ID: |
29592873
|
| Enhancer experiment: |
RNA isolation and quantitative real_x0002_time PCR (qRT-PCR)?Luciferase reporter assay?20S proteasome activity assay |
| Enhancer experiment description: |
These results suggest that CLU is a novel regulator of adipocyte differentiation by modulating the protein stability of the adipogenic transcription factor KLF5. |
About Target gene
| Target gene : |
KLF5(BTEB2,CKLF,IKLF) |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
These results suggest that CLU is a novel regulator of adipocyte differentiation by modulating the protein stability of the adipogenic transcription factor KLF5. |
About TF
| TF name : |
-- |
| TF experiment: |
RNA isolation and quantitative real_x0002_time PCR (qRT-PCR)?Luciferase reporter assay?20S proteasome activity assay |
| TF experiment description: |
These results suggest that CLU is a novel regulator of adipocyte differentiation by modulating the protein stability of the adipogenic transcription factor KLF5. |
About Function
| Enhancer function : |
These results suggest that CLU is a novel regulator of adipocyte differentiation by modulating the protein stability of the adipogenic transcription factor KLF5. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
These results suggest that CLU is a novel regulator of adipocyte differentiation by modulating the protein stability of the adipogenic transcription factor KLF5. |
About SNP
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs