About Enhancer
| Enhancer ID: |
E_02_0053 |
| Species: |
human |
| Position :
|
chr16:88712787-88714787
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Osteoporotic fracture |
| Pubmed ID: |
31968281
|
| Enhancer experiment: |
Luciferase reporter assay, chip qPCR |
| Enhancer experiment description: |
Our results first suggested that SNP rs62048221 might mediate the PIEZO1 expression level via modulating the activity of cis-regulatory elements and then further affect the BMD. |
About Target gene
| Target gene : |
PIEZO1 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Our results first suggested that SNP rs62048221 might mediate the PIEZO1 expression level via modulating the activity of cis-regulatory elements and then further affect the BMD. |
About TF
| TF name : |
-- |
| TF experiment: |
?????????ChIP-qPCR |
| TF experiment description: |
Our results first suggested that SNP rs62048221 might mediate the PIEZO1 expression level via modulating the activity of cis-regulatory elements and then further affect the BMD. |
About Function
| Enhancer function : |
Our results first suggested that SNP rs62048221 might mediate the PIEZO1 expression level via modulating the activity of cis-regulatory elements and then further affect the BMD. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Our results first suggested that SNP rs62048221 might mediate the PIEZO1 expression level via modulating the activity of cis-regulatory elements and then further affect the BMD. |
About SNP
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs