About Enhancer
| Enhancer ID: |
E_01_0758 |
| Species: |
human |
| Position :
|
chr12:102954801-102956801
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Lung adenocarcinoma, lung squamous cell carcinoma |
| Pubmed ID: |
30121393
|
| Enhancer experiment: |
RNA-seq,RT-PCR |
| Enhancer experiment description: |
ABSTRACT Introduction: A subgroup of lung adenocarcinoma shows neuroendocrine differentiation and expression of achaete- scute family bHLH transcription factor 1 (ASCL1), common to high-grade neuroendocrine tumors, small-cell lung can- cer and large cell neuroendocrine carcinoma. |
About Target gene
| Target gene : |
-- |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
ABSTRACT Introduction: A subgroup of lung adenocarcinoma shows neuroendocrine differentiation and expression of achaete- scute family bHLH transcription factor 1 (ASCL1), common to high-grade neuroendocrine tumors, small-cell lung can- cer and large cell neuroendocrine carcinoma. |
About TF
| TF name : |
ASCL1(AI225900,ASH1,Mash1,bHLHa46) |
| TF experiment: |
RNA-seq,RT-PCR |
| TF experiment description: |
ABSTRACT Introduction: A subgroup of lung adenocarcinoma shows neuroendocrine differentiation and expression of achaete- scute family bHLH transcription factor 1 (ASCL1), common to high-grade neuroendocrine tumors, small-cell lung can- cer and large cell neuroendocrine carcinoma. |
About Function
| Enhancer function : |
ABSTRACT Introduction: A subgroup of lung adenocarcinoma shows neuroendocrine differentiation and expression of achaete- scute family bHLH transcription factor 1 (ASCL1), common to high-grade neuroendocrine tumors, small-cell lung can- cer and large cell neuroendocrine carcinoma. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
ABSTRACT Introduction: A subgroup of lung adenocarcinoma shows neuroendocrine differentiation and expression of achaete- scute family bHLH transcription factor 1 (ASCL1), common to high-grade neuroendocrine tumors, small-cell lung can- cer and large cell neuroendocrine carcinoma. |
About SNP
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs