About Enhancer
| Enhancer ID: | E_01_0165 |
| Species: | human |
| Position : | chr20:56626718-56628718   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Mammary cancer |
| Pubmed ID: | 31215771 |
| Enhancer experiment: | PCR |
| Enhancer experiment description: | We found that the cooperations between regulators were much closer in lung?metastatic cells. Moreover,regulators such as TFAP2C, GTF2I and LMO4 were found to have potential prognostic value for lung metastasis free (LMF) survival of breast cancer. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | We found that the cooperations between regulators were much closer in lung?metastatic cells. Moreover,regulators such as TFAP2C, GTF2I and LMO4 were found to have potential prognostic value for lung metastasis free (LMF) survival of breast cancer. |
About TF
| TF name : | TFAP2C(AP2-GAMMA,ERF1,TFAP2G,hAP-2g) |
| TF experiment: | PCR |
| TF experiment description: | We found that the cooperations between regulators were much closer in lung?metastatic cells. Moreover,regulators such as TFAP2C, GTF2I and LMO4 were found to have potential prognostic value for lung metastasis free (LMF) survival of breast cancer. |
About Function
| Enhancer function : | We found that the cooperations between regulators were much closer in lung?metastatic cells. Moreover,regulators such as TFAP2C, GTF2I and LMO4 were found to have potential prognostic value for lung metastasis free (LMF) survival of breast cancer. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
We found that the cooperations between regulators were much closer in lung?metastatic cells. Moreover,regulators such as TFAP2C, GTF2I and LMO4 were found to have potential prognostic value for lung metastasis free (LMF) survival of breast cancer. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| TFAP2C | Validated transcriptional targets of TAp63 isoforms | pid | 54 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene