TF information

TF name: NFIL3
TF family: TF_bZIP
Ensembl gene ID: ENSG00000165030
Ensembl protein ID: ENSP00000297689
Entrez gene ID: 4783
Database name Link Database name Link
NCBI Gene: Genecards:
Uniprot: Wikipedia:
Cosmic 3D: Geneontology:
CCLE:

Frequency of NFIL3 in all biosamples
Sample ID Biosample type Tissue type Biosample name TF Frequency
Sample_02_258OtherLungNCI-H1299_EGFP-NEO_reporter_cells_DMSO0.16666666666667

NFIL3 distribution in samples’ most representative CRC
Sample ID Tissue type Biosample type Biosample name
Sample_02_258LungOtherNCI-H1299_EGFP-NEO_reporter_cells_DMSO

NFIL3 distribution in all CRCs
Biosample type
Biosample name
Sample ID

Genomic distribution of SEs associated with NFIL3
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Mutation of NFIL3
Database name Link
gnomAD: gnomAD
ExAC: ExAC
ICGC:
Database name Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of NFIL3

rsID Chr Start Stop Ref Alt Gene_region Gene_symble Effect TCGA_Occurrence
-chr99417171894171718CTexonicNFIL3synonymous LUAD|1|543|0.00184
-chr99417289194172891ACexonicNFIL3synonymous BRCA|1|982|0.00102
-chr99417248794172487GTexonicNFIL3nonsynonymous UCEC|1|248|0.00403
-chr99417225994172259GAexonicNFIL3nonsynonymous PAAD|1|185|0.00541
-chr99417277994172779T-exonicNFIL3frameshift PAAD|15|185|0.08108
-chr99417242694172426TGexonicNFIL3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr99417219394172193GAexonicNFIL3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs200055387chr99417192194171921CTexonicNFIL3nonsynonymous UCEC|2|248|0.00806
rs747568975chr99417183394171833GAexonicNFIL3nonsynonymous UCEC|2|248|0.00806
-chr99417292894172928GTexonicNFIL3nonsynonymous UCEC|1|248|0.00403
-chr99417227294172272CTexonicNFIL3nonsynonymous GBM|1|290|0.00345,GBMLGG|1|820|0.00122
-chr99417235294172352GAexonicNFIL3nonsynonymous UCEC|1|248|0.00403
-chr99417266594172665CGexonicNFIL3nonsynonymous BLCA|1|396|0.00253
-chr99417176594171765TGexonicNFIL3nonsynonymous LUAD|1|543|0.00184
-chr99417270994172709TCexonicNFIL3nonsynonymous LUSC|1|178|0.00562
rs34945709chr99417192794171927CTexonicNFIL3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,HNSC|1|512|0.00195,UCS|1|57|0.01754
-chr99417283594172835CAexonicNFIL3nonsynonymous LUAD|4|543|0.00737
rs141662610chr99417197394171973CTexonicNFIL3synonymous ACC|1|90|0.01111,COAD|1|367|0.00272,COADREAD|1|489|0.00204,ESCA|1|185|0.00541
-chr99417224994172249TCexonicNFIL3synonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr99417168894171688CAexonicNFIL3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
-chr99417210494172104GCexonicNFIL3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr99417172294171722TCexonicNFIL3nonsynonymous HNSC|1|512|0.00195
-chr99417167194171671CTexonicNFIL3nonsynonymous SKCM|1|368|0.00272
-chr99417168194171681AGexonicNFIL3nonsynonymous LIHC|1|373|0.00268
-chr99417213594172135GAexonicNFIL3synonymous SKCM|1|368|0.00272
-chr99417298594172985TAexonicNFIL3nonsynonymous LUSC|1|178|0.00562
-chr99417198394171983AGexonicNFIL3nonsynonymous UCEC|1|248|0.00403
-chr99417188194171881GTexonicNFIL3nonsynonymous UCEC|1|248|0.00403
-chr99417265594172655GAexonicNFIL3nonsynonymous SKCM|1|368|0.00272
rs368413458chr99417268094172680CTexonicNFIL3nonsynonymous UCEC|1|248|0.00403
-chr99417203094172030GCexonicNFIL3nonsynonymous CESC|1|194|0.00515
rs201995681chr99417192294171922GAexonicNFIL3synonymous UCEC|2|248|0.00806
rs778918695chr99417220194172201CTexonicNFIL3synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs754890659chr99417291894172918CTexonicNFIL3synonymous HNSC|1|512|0.00195
-chr99417230794172307CTexonicNFIL3nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr99417223794172237-GexonicNFIL3frameshift KIPAN|1|799|0.00125,KIRC|1|451|0.00222
-chr99417299094172990GAexonicNFIL3synonymous BLCA|1|396|0.00253
-chr99417274194172741CGexonicNFIL3nonsynonymous BRCA|1|982|0.00102
-chr99417179994171799TCexonicNFIL3synonymous UCEC|1|248|0.00403
-chr99417265994172659GAexonicNFIL3nonsynonymous ESCA|1|185|0.00541
-chr99417247494172474GTexonicNFIL3nonsynonymous LUAD|1|543|0.00184
-chr99417188794171887GAexonicNFIL3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr99417181394171813CAexonicNFIL3stopgain COADREAD|1|489|0.00204,READ|1|122|0.00820
-chr99417186994171869ATexonicNFIL3nonsynonymous BLCA|1|396|0.00253
-chr99417228894172288GAexonicNFIL3synonymous BLCA|1|396|0.00253
rs766517635chr99417252594172525GAexonicNFIL3synonymous STAD|1|395|0.00253,STES|1|395|0.00253
rs142483577chr99417251094172510CTexonicNFIL3synonymous UCEC|1|248|0.00403
rs780376344chr99417245394172453GAexonicNFIL3synonymous LUAD|1|543|0.00184
-chr99417254694172546GAexonicNFIL3synonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204
rs773522463chr99417293594172935GAexonicNFIL3nonsynonymous LUSC|1|178|0.00562
rs771637370chr99417182294171822GAexonicNFIL3nonsynonymous STAD|1|395|0.00253,STES|1|395|0.00253
-chr99417220294172202GAexonicNFIL3nonsynonymous UCEC|1|248|0.00403
-chr99417229994172299TCexonicNFIL3nonsynonymous UCS|1|57|0.01754
-chr99417274594172745CTexonicNFIL3nonsynonymous COAD|1|367|0.00272,COADREAD|1|489|0.00204,UCEC|1|248|0.00403
-chr99417225094172250GCexonicNFIL3stopgain PRAD|1|499|0.00200
-chr99417234094172340TCexonicNFIL3nonsynonymous KIPAN|2|799|0.00250,KIRC|2|451|0.00443
-chr99417214694172146CTexonicNFIL3nonsynonymous SKCM|1|368|0.00272
rs755160396chr99417262394172623TCexonicNFIL3nonsynonymous GBMLGG|1|820|0.00122,LGG|1|530|0.00189
-chr99417190794171907GAexonicNFIL3synonymous UCEC|1|248|0.00403

Disease information of NFIL3
TF_name Disease_name Disease_class Disease_semantic_type TF_disease_source
NFIL3 Delayed Sleep Phase Syndrome C10;C24;F03 Disease or Syndrome CTD_human
NFIL3 Nonorganic Sleep Wake Cycle Disorders C10;C24;F03 Mental or Behavioral Dysfunction CTD_human
NFIL3 Advanced Sleep Phase Syndrome C10;C24;F03 Disease or Syndrome CTD_human
NFIL3 Non-24 Hour Sleep-Wake Disorder C10;C24;F03 Mental or Behavioral Dysfunction CTD_human
NFIL3 Shift-Work Sleep Disorder C10;C24;F03 Mental or Behavioral Dysfunction CTD_human
NFIL3 Sleep Disorders, Circadian Rhythm C10;C24;F03 Pathologic Function CTD_human

Pathway associated with NFIL3
pathway_ID pathway_name pathway_source gene_number edge_number

Go term information of NFIL3
GO_term_name GO_term_type TF_name
GO_CIRCADIAN_RHYTHM BP NFIL3
GO_RESPONSE_TO_INTERLEUKIN_4 BP NFIL3
GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION BP NFIL3
GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_4 BP NFIL3
GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER BP NFIL3
GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER BP NFIL3
GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING MF NFIL3
GO_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING MF NFIL3
GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING MF NFIL3
GO_SEQUENCE_SPECIFIC_DNA_BINDING MF NFIL3
GO_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING MF NFIL3

Survival analysis of NFIL3



Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.

Expression of NFIL3