| CR | Function | Accession | Protein_names | ENTREZ_ID | Aliases | PMID | Function type | Histone type | Methytor type | Sample information |
|---|---|---|---|---|---|---|---|---|---|---|
| ALKBH1 | Histone modification;DNA modification(DNA methylation editor/eraser) | Q13686 | Nucleic acid dioxygenase ALKBH1 | 8846 | alkylation repair homolog | 27745969.. | DNA Methylator,Histone Modifier | Unkown | Eraser | |
| ATF7IP | Histone modification write cofactor(Histone methylation);Mediates MBD1 transcriptional repression, couples H3K9me3 with DNA methylation. | Q6VMQ6 | Activating transcription factor 7-interacting protein 1 | 55729 | DNA methyltransferases | 31217192.. | DNA Methylator,Histone Modifier | Writer | Unkown | |
| DNMT3L | Histone modification read;DNA modification(De novo methylation);Catalytically inactive, but essential for DNMT3A and DNMT3B function. | Q9UJW3 | DNA (cytosine-5)-methyltransferase 3-like | 29947 | DNA (cytosine-5-)-methyltransferase 3(DNMT);DNA methyltransferases | 30321403.. | DNA Methylator,Histone Modifier | Reader | Writer | |
| MBD1 | Histone modification write cofactor, TF(Histone methylation, TF repressor);DNA modification(DNA methylation reader);Essential for embryonic development. Specifically bind methylated DNA and repress transcription at methylated promoters. | Q9UIS9 | Methyl-CpG-binding domain protein 1 | 4152 | Methyl-CpG-Binding Protein (MBD);DNA methyltransferases;DNMT-MBD | 30849389.. | DNA Methylator,Histone Modifier | Writer | Reader | |
| MBD2 | Histone modification write cofactor, Histone modification erase cofactor, TF(Histone methylation, Histone acetylation, TF repressor);DNA modification(DNA methylation reader);Essential for embryonic development. Also bind methylated DNA. | Q9UBB5 | Methyl-CpG-binding domain protein 2 | 8932 | NuRD, MeCP1;Methyl-CpG-Binding Protein (MBD);ATP-dependent chromatin remodelling;DNMT-MBD | 33277324.. | DNA Methylator,Histone Modifier | Writer,Eraser | Reader | |
| MBD3 | Histone modification erase cofactor(Histone acetylation);DNA modification(DNA methylation reader) | O95983 | Methyl-CpG-binding domain protein 3 | 53615 | NuRD;Methyl-CpG-Binding Protein (MBD);DNMT-MBD | 30122475.. | DNA Methylator,Histone Modifier | Eraser | Reader | |
| MECP2 | Histone modification write cofactor, Histone modification write cofactor, TF(Histone methylation, Histone acetylation, TF repressor);DNA modification(DNA methylation reader) | P51608 | Methyl-CpG-binding protein 2 | 4204 | Methyl-CpG-Binding Protein (MBD);DNA methyltransferases;DNMT-MBD | 31784358.. | DNA Methylator,Histone Modifier | Writer | Reader | |
| PRDM14 | DNA modification(DNA demethylation);Histone Modification(Histone methyltransferases) | Q9GZV8 | PR domain-containing 14 | 63978 | PR domain containing;SET-HMT | 24811060.. | DNA Methylator,Histone Modifier | Unkown | Eraser | |
| UHRF1 | Histone modification read, Histone modification write cofactor(Histone ubiquitination);DNA modification(DNA methylation reader) | Q96T88 | Alternative protein UHRF1 | 29128 | ubiquitin-like with PHD and ring finger domains 1;RING finger | 34561619.. | DNA Methylator,Histone Modifier | Reader,Writer | Reader | |
| USP7 | Histone modification erase, DNA modification cofactor(Histone ubiquitination, DNA methylation) | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | 7874 | TEF1; HAUSP | 29045385.. | DNA Methylator,Histone Modifier | Eraser | Unkown | |
| ZBTB33 | Histone modification write cofactor, Histone modification erase cofactor, TF(Histone acetylation, Histone methylation, TF repressor);DNA modification(DNA methylation reader) | Q86T24 | Alternative protein ZBTB33 | 10009 | Zinc finger and BTB domain containing(ZBTB) | 33526872.. | DNA Methylator,Histone Modifier | Writer,Eraser | Reader |