| CR | Function | Accession | Protein_names | ENTREZ_ID | Aliases | PMID | Function type | Histone type | Methytor type | Sample information |
|---|---|---|---|---|---|---|---|---|---|---|
| ASXL1 | Histone modification erase, Polycomb group (PcG) protein(Histone deubiquitination);Associates with PRC2 to promote gene repression. | Q8IXJ9 | Polycomb group protein ASXL1 | 171023 | PR-DUB;Polycomb Repressive Complex 2 | 34699595.. | Histone Modifier | Eraser | Unkown | |
| ATN1 | Histone modification erase cofactor | P54259 | Atrophin 1 | 1822 | Unkown | 30827498.. | Histone Modifier | Eraser | Unkown | |
| ATXN7L3 | Histone modification erase cofactor(Histone deubiquitination) | Q14CW9 | Alternative protein ATXN7L3 | 56970 | SAGA | 35192684.. | Histone Modifier | Eraser | Unkown | |
| BABAM1 | Histone modification erase cofactor(Histone deubiquitination) | Q9NWV8 | BRISC and BRCA1-A complex member 1 | 29086 | BRISC, BRCA1-A | 33545059.. | Histone Modifier | Eraser | Unkown | |
| BAP1 | Histone modification erase, Polycomb group (PcG) protein(Histone deubiquitination);Catalytic component of the PR-DUB complex, that specifically deubiquitinates H2AK119ub1. | Q92560 | Ubiquitin carboxyl-terminal hydrolase BAP1 | 8314 | PR-DUB;Polycomb Repressive Complex 1 | 28614305.. | Histone Modifier | Eraser | Unkown | |
| BAZ2A | Chromatin remodelling, Histone modification erase( Histone deacetylation) | Q9UIF9 | Bromodomain adjacent to zinc finger domain protein 2A | 11176 | NoRC;ATP-dependent chromatin remodelling;Bromo-PHD | 25485837.. | Histone Modifier,Chromatin Remodeler | Eraser | Unkown | |
| BCORL1 | Histone modification erase cofactor(Histone deacetylation) | Q5H9F3 | BCORL1 protein | 63035 | BCOR | 33945606.. | Histone Modifier | Eraser | Unkown | |
| BRCC3 | Histone modification erase(Histone deubiquitination) | P46736 | Lys-63-specific deubiquitinase BRCC36 | 79184 | BRISC, BRCA1-A | 23246432.. | Histone Modifier | Eraser | Unkown | |
| BRMS1L | Histone modification erase(Histone deacetylation) | Q5PSV4 | Breast cancer metastasis-suppressor 1-like protein (BRMS1-homolog protein p40) (BRMS1-like protein p40) | 84312 | mSin3A | 25406648.. | Histone Modifier | Eraser | Unkown | |
| C14orf169 | Histone modification erase(Histone methylation) | Q9H6W3 | Ribosomal oxygenase 1 | 79697 | Unkown | 33745927.. | Histone Modifier | Eraser | Unkown | |
| DNAJC1 | Histone modification write cofactor, Histone modification erase cofactor(Histone acetylation, Histone deacetylation) | Q96KC8 | DnaJ homolog subfamily C member 1 (DnaJ homolog subfamily C member 1 variant 3) (DnaJ homolog subfamily C member 1 variant 4) | 64215 | Unkown | 26480920.. | Histone Modifier | Writer,Eraser | Unkown | |
| EID2B | Histone modification erase cofactor(Histone acetylation) | Q96D98 | EP300-interacting inhibitor of differentiation 2B | 126272 | Unkown | 26186194.. | Histone Modifier | Eraser | Unkown | |
| ENY2 | Histone modification erase cofactor(Histone ubiquitination) | Q9NPA8 | Transcription and mRNA export factor ENY2 | 56943 | SAGA | 20048002.. | Histone Modifier | Eraser | Unkown | |
| EYA1 | Histone modification erase(Histone phosphorylation);Histone Modification(Phosphorylation editor) | Q99502 | Eyes absent homolog (EC 3.1.3.48) | 2138 | eyes absent (EYA) family | 34864618.. | Histone Modifier | Eraser | Unkown | |
| EYA2 | Histone modification erase(Histone phosphorylation);Histone Modification(Phosphorylation editor) | O00167 | Putative regulatory uORF | 2139 | eyes absent (EYA) family | 34044846.. | Histone Modifier | Eraser | Unkown | |
| EYA3 | Histone modification erase(Histone phosphorylation);Histone Modification(Phosphorylation editor) | Q99504 | Eyes absent homolog 3 (EC 3.1.3.48) | 2140 | eyes absent (EYA) family | 29884726.. | Histone Modifier | Eraser | Unkown | |
| EYA4 | Histone modification erase(Histone phosphorylation);Histone Modification(Phosphorylation editor) | O95677 | Eyes absent homolog (EC 3.1.3.48) | 2070 | eyes absent (EYA) family | 31101108.. | Histone Modifier | Eraser | Unkown | |
| FAM175B | Histone modification erase cofactor(Histone ubiquitination) | Q15018 | BRISC complex subunit Abraxas 2 | 23172 | BRISC | 30854784 | Histone Modifier | Eraser | Unkown | |
| GSE1 | Histone modification erase(Histone acetylation) | Q14687 | Genetic suppressor element 1 | 23199 | BHC, LSD-CoREST | 34862459.. | Histone Modifier | Eraser | Unkown | |
| HDAC1 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser);Eraser | Q13547 | Histone deacetylase 1 | 3065 | SWI/SNF_Brm, NuRD, BHC, MeCP1, mSin3A, core HDAC, mSin3A-like complex, RING2-L3MBTL2, CREST-BRG1, LSD-CoREST;Histone deacetylase (HDAC);ATP-dependent chromatin remodelling;HDAC | 31913353.. | Histone Modifier | Eraser | Unkown | |
| HDAC10 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | Q969S8 | Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (HD10) | 83933 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 32540961.. | Histone Modifier | Eraser | Unkown | |
| HDAC11 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | Q96DB2 | Histone deacetylase 11 | 79885 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 32661313.. | Histone Modifier | Eraser | Unkown | |
| HDAC2 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser);Eraser | Q92769 | Histone deacetylase 2 | 3066 | SWI/SNF_Brg1(I), SWI/SNF_Brg1(II), SWI/SNF_Brm, NuRD, BHC, MeCP1, mSin3A, core HDAC, mSin3A-like complex, RING2-L3MBTL2, LSD-CoREST;Histone deacetylase (HDAC);ATP-dependent chromatin remodelling;HDAC | 19424149.. | Histone Modifier | Eraser | Unkown | |
| HDAC3 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser);Modulation of cell growth and apoptosis by down-regulation of p53.;Eraser | O15379 | Histone deacetylase 3 | 8841 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 32731255.. | Histone Modifier | Eraser | Unkown | |
| HDAC4 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | P56524 | Histone deacetylase (EC 3.5.1.98) | 9759 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 30503143.. | Histone Modifier | Eraser | Unkown | |
| HDAC5 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | Q9UQL6 | Histone deacetylase (EC 3.5.1.98) | 10014 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 32612176.. | Histone Modifier | Eraser | Unkown | |
| HDAC6 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser);Eraser | Q9UBN7 | Histone deacetylase 6 | 10013 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 12024216.. | Histone Modifier | Eraser | Unkown | |
| HDAC7 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | Q8WUI4 | Histone deacetylase 7 | 51564 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 29126425.. | Histone Modifier | Eraser | Unkown | |
| HDAC8 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | Q9BY41 | Histone deacetylase (EC 3.5.1.98) | 55869 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 32315388.. | Histone Modifier | Eraser | Unkown | |
| HDAC9 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser);Protects neurons from apoptosis. | Q9UKV0 | Histone deacetylase (EC 3.5.1.98) | 9734 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 31712770.. | Histone Modifier | Eraser | Unkown | |
| HIF1AN | Histone modification erase cofactor(Histone acetylation) | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | 55662 | Unkown | 31410089.. | Histone Modifier | Eraser | Unkown | |
| HR | Histone modification erase(Histone methylation) | O43593 | Hair growth associated | 55806 | Unkown | 34636192.. | Histone Modifier | Eraser | Unkown | |
| JDP2 | Chromatin remodelling, Histone modification erase cofactor( Histone acetylation) | Q8WYK2 | Jun dimerization protein 2 | 122953 | Unkown | 31434880.. | Histone Modifier,Chromatin Remodeler | Eraser | Unkown | |
| JMJD1C | Histone modification erase(Histone methylation);Histone Modification(protein hydroxylases or histone demethylases);H3K9 HDM. | Q15652 | Probable JmjC domain-containing histone demethylation protein 2C | 221037 | jumonji domain containing;Histone demethylases;Jumonji | 30622285.. | Histone Modifier | Eraser | Unkown | |
| JMJD6 | Histone modification erase(Histone methylation);Histone Modification(protein hydroxylases or histone demethylases);H3R2, H4R3 HDM. Key regulator of haematopoietic differentiation. | Q6NYC1 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 | 23210 | jumonji domain containing;Histone demethylases;Jumonji | 31346162.. | Histone Modifier | Eraser | Unkown | |
| KDM1A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));HDM, also demethylates and stabilizes DNMT1.;Eraser | O60341 | Lysine-specific histone demethylase 1A | 23028 | NuRD, BHC, SCL;lysine (K)-specific demethylase (KDM);DNA methyltransferases;Jumonji;Jumonji | 34655521.. | Histone Modifier | Eraser | Unkown | |
| KDM1B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));HDM, required for de novo DNA methylation of a subset of imprinted genes during oogenesis. | Q8NB78 | Lysine-specific histone demethylase 1B | 221656 | lysine (K)-specific demethylase (KDM);DNA methyltransferases | 26766590.. | Histone Modifier | Eraser | Unkown | |
| KDM2A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K36me2 HDM. Required to maintain heterochromatic state at centromeres.;Eraser | Q9Y2K7 | Alternative protein KDM2A | 22992 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 33462408.. | Histone Modifier | Eraser | Unkown | |
| KDM2B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K4me3, H3K36me2 HDM. Represses rRNA genes. | Q8NHM5 | Lysine-specific demethylase 2B | 84678 | BCOR;lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji;Jumonji | 31197256.. | Histone Modifier | Eraser | Unkown | |
| KDM3A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9me2/me1 HDM. | Q9Y4C1 | Lysine-specific demethylase 3A | 55818 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 31629659.. | Histone Modifier | Eraser | Unkown | |
| KDM3B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9 HDM. | Q7LBC6 | Lysine-specific demethylase 3B | 51780 | lysine (K)-specific demethylase (KDM);Histone demethylases | 30929739.. | Histone Modifier | Eraser | Unkown | |
| KDM4A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9me3, H3K36me3 HDM.;Eraser | O75164 | Alternative protein KDM4A | 9682 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 32231309.. | Histone Modifier | Eraser | Unkown | |
| KDM4B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9me3 HDM. | O94953 | Lysine-specific demethylase 4B | 23030 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 33571444.. | Histone Modifier | Eraser | Unkown | |
| KDM4C | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9me3, H3K36me3 HDM. | Q9H3R0 | Lysine-specific demethylase 4C | 23081 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 32402251.. | Histone Modifier | Eraser | Unkown | |
| KDM4D | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9me3/me2 HDM. | Q6B0I6 | Lysine-specific demethylase 4D | 55693 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 30060750.. | Histone Modifier | Eraser | Unkown | |
| KDM4E | Histone modification erase(Histone methylation) | B2RXH2 | Lysine-specific demethylase 4E | 390245 | Unkown | 29453221 | Histone Modifier | Eraser | Unkown | |
| KDM5A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K4me2/me3 HDM. Prominent role in cell differentiation and senescence (17).;Eraser | P29375 | Lysine-specific demethylase 5A | 5927 | lysine (K)-specific demethylase (KDM);Histone demethylases | 33596982.. | Histone Modifier | Eraser | Unkown | |
| KDM5B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K4me3/me2/me1 HDM.;Eraser | Q9UGL1 | Lysine-specific demethylase 5B | 10765 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 34671158.. | Histone Modifier | Eraser | Unkown | |
| KDM5C | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K4me3/me2 HDM. Participates in the repression of neuronal genes.;Eraser | P41229 | [Histone H3]-trimethyl-L-lysine(4) demethylase (EC 1.14.11.67) | 8242 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 31221981.. | Histone Modifier | Eraser | Unkown | |
| KDM5D | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K4me3/me2 HDM. | Q9BY66 | [Histone H3]-trimethyl-L-lysine(4) demethylase (EC 1.14.11.67) | 8284 | lysine (K)-specific demethylase (KDM);Histone demethylases | 29863497.. | Histone Modifier | Eraser | Unkown | |
| KDM6A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K27me2/me3 HDM. Regulation of HOX gene expression. | O15550 | Lysine-specific demethylase 6A | 7403 | CHD8, MLL2/3, MLL4/WBP7, COMPASS-like MLL3,4;lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 30872525.. | Histone Modifier | Eraser | Unkown | |
| KDM6B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K27me2/me3 HDM. Regulation of HOX gene expression.;Eraser | O15054 | Lysine-specific demethylase 6B | 23135 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 32299951.. | Histone Modifier | Eraser | Unkown | |
| KDM7A | Histone modification erase(Histone methylation) | Q6ZMT4 | Lysine-specific demethylase 7A | 80853 | Jumonji | 32935279.. | Histone Modifier | Eraser | Unkown | |
| KDM8 | Histone modification erase(Histone methylation);H3K36me2 HDM. Required for G2/M cell cycle progression. | Q8N371 | Bifunctional peptidase and arginyl-hydroxylase JMJD5 | 79831 | Histone demethylases;Jumonji | 20457893.. | Histone Modifier | Eraser | Unkown | |
| MBD2 | Histone modification write cofactor, Histone modification erase cofactor, TF(Histone methylation, Histone acetylation, TF repressor);DNA modification(DNA methylation reader);Essential for embryonic development. Also bind methylated DNA. | Q9UBB5 | Methyl-CpG-binding domain protein 2 | 8932 | NuRD, MeCP1;Methyl-CpG-Binding Protein (MBD);ATP-dependent chromatin remodelling;DNMT-MBD | 33277324.. | DNA Methylator,Histone Modifier | Writer,Eraser | Reader | |
| MBD3 | Histone modification erase cofactor(Histone acetylation);DNA modification(DNA methylation reader) | O95983 | Methyl-CpG-binding domain protein 3 | 53615 | NuRD;Methyl-CpG-Binding Protein (MBD);DNMT-MBD | 30122475.. | DNA Methylator,Histone Modifier | Eraser | Reader | |
| MINA | Histone modification erase(Histone methylation) | Q81UF8 | Ribosomal oxygenase 2 | 84864 | Unkown | 30728462.. | Histone Modifier | Eraser | Unkown | |
| MORF4L2 | Histone modification erase cofactor(Histone acetylation) | Q15014 | Mortality factor 4-like protein 2 | 9643 | NuA4;MRG | 35900839.. | Histone Modifier | Eraser | Unkown | |
| MTA2 | Histone modification erase cofactor(Histone acetylation) | O94776 | Metastasis-associated protein MTA2 | 9219 | NuRD;ATP-dependent chromatin remodelling;Bromo-PHD | 24010737.. | Histone Modifier | Eraser | Unkown | |
| MYSM1 | Histone modification erase(Histone ubiquitination) | Q5VVJ2 | Deubiquitinase MYSM1 | 114803 | Unkown | 33240758.. | Histone Modifier | Eraser | Unkown | |
| NCOR1 | Histone modification erase cofactor(Histone acetylation);Forms complex with HDAC1. | O75376 | NCOR1 protein | 9611 | Histone deacetylases | 31529020.. | Histone Modifier | Eraser | Unkown | |
| NCOR2 | Histone modification erase cofactor(Histone acetylation) | Q9Y618 | Nuclear receptor corepressor 2 | 9612 | Unkown | 29262348.. | Histone Modifier | Eraser | Unkown | |
| NIPBL | Histone modification erase cofactor(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q6KC79 | Nipped-B-like protein | 25836 | Nipped-B homolog | 32409525.. | Histone Modifier | Reader,Eraser | Unkown | |
| PHF12 | Histone modification erase cofactor(Histone acetylation) | Q96QT6 | PHD finger protein 12 | 57649 | Bromo-PHD | 27956701.. | Histone Modifier | Eraser | Unkown | |
| PHF2 | Histone modification erase(Histone methylation);Histone Modification(K4 reader);H3K9me2 HDM. | O75151 | Lysine-specific demethylase PHF2 | 5253 | PHD finger protein;Histone demethylases;Jumonji;Jumonji | 32232336.. | Histone Modifier | Eraser | Unkown | |
| PHF21A | Histone modification erase cofactor(Histone methylation) | Q96BD5 | PHD finger protein 21A | 51317 | BHC, LSD-CoREST;Bromo-PHD | 22770980.. | Histone Modifier | Eraser | Unkown | |
| PHF8 | Histone modification erase(Histone methylation);Histone Modification(K4 reader);H3K9me1/me2, H3K27me2, H4K20me1 HDM. Key role in cell cycle progression.;Eraser | Q9UPP1 | Histone lysine demethylase PHF8 | 23133 | PHD finger protein;Histone demethylases;Jumonji;Jumonji | 33010150.. | Histone Modifier | Reader,Eraser | Unkown | |
| PIWIL4 | Chromatin remodelling, Histone modification erase cofactor( Histone methylation) | Q7Z3Z4 | Piwi-like protein 4 | 143689 | Unkown | 35609598.. | Histone Modifier,Chromatin Remodeler | Eraser | Unkown | |
| PPP4C | Histone modification erase(Histone phosphorylation) | P60510 | Serine/threonine-protein phosphatase (EC 3.1.3.16) | 5531 | PPP4C-PPP4R2-PPP4R3A | 35546066.. | Histone Modifier | Eraser | Unkown | |
| PPP4R3A | Histone modification erase cofactor(Histone phosphorylation);Histone Modification(Phosphorylation editor) | Q6IN85 | Serine/threonine-protein phosphatase 4 regulatory subunit 3A | 55671 | PPP4C-PPP4R2-PPP4R3A;SMEK homolog | 29130521.. | Histone Modifier | Eraser | Unkown | |
| PPP4R3B | Histone modification erase cofactor(Histone phosphorylation);Histone Modification(Phosphorylation editor) | Q5MIZ7 | Serine/threonine-protein phosphatase 4 regulatory subunit 3B | 57223 | SMEK homolog | 20876121.. | Histone Modifier | Eraser | Unkown | |
| RAD51 | Histone modification erase(Histone ubiquitination) | Q06609 | DNA repair protein RAD51 homolog 1 | 5888 | BRCC | 28976962.. | Histone Modifier | Eraser | Unkown | |
| RCOR1 | Histone modification erase cofactor, Histone modification erase cofactor(Histone acetylation, Histone methylation) | Q9UKL0 | Alternative protein RCOR1 | 23186 | BHC, SCL, LSD-CoREST;SANT domain | 24652990.. | Histone Modifier | Eraser | Unkown | |
| RCOR3 | Histone modification erase cofactor(Histone acetylation) | Q9P2K3 | REST corepressor 3 | 55758 | LSD-CoREST;SANT domain | 21258344.. | Histone Modifier | Eraser | Unkown | |
| RERE | Histone lysine demethylase PHF8 | Q9P2R6 | Arginine-glutamic acid dipeptide repeats protein | 473 | Unkown | 20164929 | Histone Modifier | Eraser | Unkown | |
| REST | Histone modification erase cofactor, TF, TF(Histone acetylation, TF activator, TF repressor) | Q13127 | RE1-silencing transcription factor variant E1c/E2g/E3/E4 | 5978 | Unkown | 34625348.. | Histone Modifier | Eraser | Unkown | |
| RIOX2 | Histone modification erase | Q8IUF8 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase (EC 1.14.11.-) | 84864 | ROX; MDIG; MINA; NO52; JMJD10; MINA53 | 34855761.. | Histone Modifier | Eraser | Unkown | |
| RLIM | Histone modification erase cofactor(Histone acetylation) | Q9NVW2 | E3 ubiquitin-protein ligase RLIM | 51132 | Unkown | 33328571.. | Histone Modifier | Eraser | Unkown | |
| SAP130 | Histone modification erase cofactor(Histone acetylation) | Q9H0E3 | Histone deacetylase complex subunit SAP130 | 79595 | Unkown | 34556635.. | Histone Modifier | Eraser | Unkown | |
| SAP18 | Histone modification erase cofactor(Histone acetylation) | O00422 | Histone deacetylase complex subunit SAP18 | 10284 | mSin3A | 9150135;30670829 | Histone Modifier | Eraser | Unkown | |
| SAP25 | Histone modification erase cofactor(Histone acetylation) | Q8TEE9 | Histone deacetylase complex subunit SAP25 | 100316904 | Unkown | 16449650 | Histone Modifier | Eraser | Unkown | |
| SAP30 | Histone modification erase cofactor(Histone acetylation) | O75446 | Histone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30) | 8819 | mSin3A, mSin3A-like complex | 32820380 | Histone Modifier | Eraser | Unkown | |
| SAP30L | Histone modification erase cofactor(Histone acetylation) | Q9HAJ7 | Histone deacetylase complex subunit SAP30L | 79685 | Unkown | 30820959 | Histone Modifier | Eraser | Unkown | |
| SENP1 | Histone modification erase cofactor(Histone sumoylation) | Q9P0U3 | Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1) | 29843 | Unkown | 28258134.. | Histone Modifier | Eraser | Unkown | |
| SENP3 | Histone modification erase, Histone modification write cofactor(Histone sumoylation, Histone acetylation) | Q9H4L4 | Sentrin-specific protease 3 | 26168 | CHD8, MLL2/3, MLL4/WBP7 | 32351703.. | Histone Modifier | Writer,Eraser | Unkown | |
| SIN3A | Histone modification erase cofactor, TF, TF(Histone acetylation, TF activator, TF repressor) | Q96ST3 | Paired amphipathic helix protein Sin3a | 25942 | SWI/SNF_Brg1(I), SWI/SNF_Brm, mSin3A, mSin3A-like complex;HDAC | 34078089.. | Histone Modifier | Eraser | Unkown | |
| SIN3B | Histone modification erase cofactor, TF(Histone acetylation, TF repressor) | Q62141 | Paired amphipathic helix protein Sin3b | 23309 | mSin3A;HDAC | 28807943.. | Histone Modifier | Eraser | Unkown | |
| SIRT1 | Histone modification erase, Histone modification write cofactor(Histone acetylation, Histone methylation);Histone Modification(acetylation editor);Interacts with PRC2, non-histone deacetylase activity. Involved in normal ageing through resistance to cellular stress. Deacetylates p53. Located in nucleus and cytoplasm;Eraser | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | 23411 | eNoSc;sirtuin family;Histone deacetylases;HDAC | 28701484.. | Histone Modifier | Writer,Eraser | Unkown | |
| SIRT2 | Histone modification erase, Histone modification write cofactor(Histone acetylation, Histone methylation);Histone Modification(acetylation editor);Deacetylates alpha-tubulin. Located in the cytoplasm | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | 22933 | sirtuin family;Histone deacetylases;HDAC | 32768387.. | Histone Modifier | Writer,Eraser | Unkown | |
| SIRT6 | Histone modification erase(Histone acetylation);Histone Modification(acetylation editor);Located in the nucleus. H3K9 and H3K56 deacetylase activity.;Eraser | Q8N6T7 | NAD-dependent protein deacetylase sirtuin-6 | 51548 | sirtuin family;Histone deacetylases;HDAC | 31437090.. | Histone Modifier | Eraser | Unkown | |
| SIRT7 | Histone modification erase(Histone acetylation);Histone Modification(acetylation editor);Located in the nucleus. | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | 51547 | B-WICH;sirtuin family;Histone deacetylases;HDAC | 31970414.. | Histone Modifier | Eraser | Unkown | |
| SMARCA1 | Chromatin remodelling, Histone modification erase( Histone acetylation);Nucleosome Positioning and Remodeling(Chromatin remodelling helicase) | P28370 | SMARCA1 protein | 6594 | NuRF, CERF, CERF;SWI/SNF family;ATP-dependent chromatin remodelling;SNF2-5 | 32572232.. | Histone Modifier,Chromatin Remodeler | Eraser | Unkown | |
| SMYD4 | Histone modification erase cofactor(Histone acetylation);Histone Modification(Histone methyltransferases(HMT)) | Q8IYR2 | SET and MYND domain-containing protein 4 | 114826 | SET and MYND domain containing;SET-HMT | 32154082.. | Histone Modifier | Eraser | Unkown | |
| SNAI2 | Histone modification erase cofactor | O43623 | Zinc finger protein SNAI2 | 6591 | Unkown | 33420019.. | Histone Modifier | Eraser | Unkown | |
| SPEN | Histone modification erase cofactor, TF, TF(Histone acetylation, TF activator, TF repressor) | Q96T58 | Msx2-interacting protein | 23013 | MINT; SHARP; RBM15C; HIAA0929 | 32025035.. | Histone Modifier | Eraser | Unkown | |
| SRCAP | Chromatin remodelling, Histone modification erase( Histone acetylation);Nucleosome Positioning and Remodeling(Chromatin remodelling helicase) | Q6ZRS2 | Helicase SRCAP | 10847 | NuA4-related complex, SRCAP;Snf2-related CREBBP activator protein | 34349258.. | Histone Modifier,Chromatin Remodeler | Eraser | Unkown | |
| SUDS3 | Histone modification erase cofactor(Histone acetylation) | Q9H7L9 | SUDS3 protein | 64426 | SDS3; SAP45 | 19070953.. | Histone Modifier | Eraser | Unkown | |
| SUPT6H | Histone modification erase cofactor(Histone methylation) | Q7KZ85 | Transcription elongation factor SPT6 | 6830 | SPT6; SPT6H; emb-5 | 24441044.. | Histone Modifier | Eraser | Unkown | |
| TLE4 | Histone modification erase cofactor, TF | Q04727 | Transducin-like enhancer protein 4 | 7091 | ESG; BCE1; ESG4; GRG4; BCE-1; Grg-4; E(spI) | 29869113.. | Histone Modifier | Eraser | Unkown | |
| TRIM27 | Histone modification erase cofactor(Histone acetylation) | P14373 | Zinc finger protein RFP | 5987 | RFP; RNF76 | 33251042.. | Histone Modifier | Eraser | Unkown | |
| UCHL5 | Histone modification erase cofactor(Histone ubiquitination) | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 51377 | UCH37; CGI-70; INO80R; UCH-L5 | 33156996.. | Histone Modifier | Eraser | Unkown | |
| USP11 | Histone modification erase cofactor(Histone ubiquitination) | P51784 | Ubiquitin carboxyl-terminal hydrolase 11 | 8237 | UHX1 | 34526504.. | Histone Modifier | Eraser | Unkown | |
| USP12 | Histone modification erase(Histone ubiquitination) | O75317 | Ubiquitin carboxyl-terminal hydrolase 12 | 219333 | UBH1; USP12L1 | 34381028.. | Histone Modifier | Eraser | Unkown | |
| USP15 | Histone modification erase(Histone ubiquitination) | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | 9958 | UNPH4; UNPH-2 | 31477895.. | Histone Modifier | Eraser | Unkown | |
| USP16 | Histone modification erase(Histone ubiquitination) | Q9Y5T5 | Ubiquitin carboxyl-terminal hydrolase 16 | 10600 | UBPM; UBP-M | 24025767.. | Histone Modifier | Eraser | Unkown | |
| USP17L2 | Histone modification erase cofactor(Histone ubiquitination) | Q6R6M4 | Ubiquitin carboxyl-terminal hydrolase 17 | 377630 | DUB3; DUB-3; USP17 | 36040642 | Histone Modifier | Eraser | Unkown | |
| USP21 | Histone modification erase(Histone ubiquitination) | Q9UK80 | Ubiquitin carboxyl-terminal hydrolase 21 | 27005 | USP16; USP23 | 31488580.. | Histone Modifier | Eraser | Unkown | |
| USP44 | Histone modification erase(Histone ubiquitination) | Q9H0E7 | Ubiquitin carboxyl-terminal hydrolase 44 | 84101 | 35079021.. | Histone Modifier | Eraser | Unkown | ||
| USP46 | Histone modification erase(Histone ubiquitination) | P62068 | Ubiquitin carboxyl-terminal hydrolase 46 | 64854 | 31632687.. | Histone Modifier | Eraser | Unkown | ||
| USP49 | Histone modification erase(Histone ubiquitination) | Q70CQ1 | Ubiquitin carboxyl-terminal hydrolase 49 | 25862 | 28363942.. | Histone Modifier | Eraser | Unkown | ||
| USP7 | Histone modification erase, DNA modification cofactor(Histone ubiquitination, DNA methylation) | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | 7874 | TEF1; HAUSP | 29045385.. | DNA Methylator,Histone Modifier | Eraser | Unkown | |
| UTY | Histone modification erase(Histone ubiquitination);Histone Modification(Histone demethylase (HDM));H3K27me3/me2/me1 HDM. | O14607 | Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 37 | 7404 | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked;Histone demethylases | 34526716.. | Histone Modifier | Eraser | Unkown | |
| YWHAB | Histone modification erase cofactor(Histone acetylation) | P31946 | 14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed] | 7529 | HS1; GW128; YWHAA; KCIP-1; HEL-S-1 | 30317584 | Histone Modifier | Eraser | Unkown | |
| YWHAE | Histone modification erase cofactor(Histone acetylation) | P62258 | 14-3-3 protein epsilon | 7531 | MDS; HEL2; MDCR; KCIP-1; 14-3-3E | 33947829 | Histone Modifier | Eraser | Unkown | |
| ZBTB16 | Histone modification erase cofactor(Histone acetylation) | Q05516 | Zinc finger and BTB domain-containing protein 16 | 7704 | PLZF; ZNF145 | 26916077.. | Histone Modifier | Eraser | Unkown | |
| ZBTB33 | Histone modification write cofactor, Histone modification erase cofactor, TF(Histone acetylation, Histone methylation, TF repressor);DNA modification(DNA methylation reader) | Q86T24 | Alternative protein ZBTB33 | 10009 | Zinc finger and BTB domain containing(ZBTB) | 33526872.. | DNA Methylator,Histone Modifier | Writer,Eraser | Reader | |
| ZMYM2 | Histone modification erase cofactor, TF(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q9UBW7 | Zinc finger MYM-type protein 2 | 7750 | BHC, LSD-CoREST;zinc finger, MYM-type | 32032525.. | Histone Modifier | Reader,Eraser | Unkown | |
| ZMYM3 | Histone modification erase cofactor(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q14202 | Zinc finger MYM-type protein 3 | 9203 | BHC;zinc finger, MYM-type | 26200345.. | Histone Modifier | Reader,Eraser | Unkown | |
| ZMYND8 | Histone modification erase cofactor(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q9ULU4 | Protein kinase C-binding protein 1 | 23613 | zinc finger, MYND-type containing 8;Bromo-PHD;Bromo-PHD | 33932349.. | Histone Modifier | Reader,Eraser | Unkown | |
| ZNF217 | Histone modification erase cofactor, TF(Histone acetylation, TF repressor) | O75362 | Zinc finger protein 217 | 7764 | ZABC1 | 32721948.. | Histone Modifier | Eraser | Unkown | |
| ZNF516 | Histone modification erase cofactor, TF(Histone acetylation, TF repressor) | Q92618 | Zinc finger protein 516 | 9658 | HsT287 | 28947780 | Histone Modifier | Eraser | Unkown | |
| ZNF532 | Histone modification erase cofactor(Histone acetylation) | K7EIU3 | Zinc finger protein 532 | 55205 | 32343678.. | Histone Modifier | Eraser | Unkown | ||
| ZNF592 | Histone modification erase cofactor(Histone acetylation) | Q92610 | Alternative protein ZNF592 | 9640 | CAMOS; SCAR5 | 26478897 | Histone Modifier | Eraser | Unkown | |
| ZNF687 | Histone modification erase cofactor(Histone acetylation) | H0Y5I5 | Zinc finger protein 687 | 57592 | 26849110.. | Histone Modifier | Eraser | Unkown | ||
| ZNF711 | Histone modification erase cofactor(Histone acetylation) | Q6PK66 | ZNF711 protein | 7552 | ZNF4; ZNF5; ZNF6; CMPX1; MRX97; Zfp711; dJ75N13.1 | 34521054 | Histone Modifier | Eraser | Unkown |