CR overview
| CR: | DOT1L | |
| Accession: | Q8TEK3 | |
| Protein names: | Histone-lysine N-methyltransferase, H3 lysine-79 specific | |
| Function type: | Histone Modifier | |
| Histone type: | Writer | |
| Methytor type: | Unkown | |
| Aliases: | DOT1-like histone H3K79 methyltransferase;Histone methyltransferases;SET-HMT | |
| PMID: | 30765112 21741597 32814769 33077595 | |
| Disease: | 1 | |
| Go term: | 19 | |
| Pathway: | 2 | |
| Hallmark: | 2 | |
| Super Enhancer: | chr19:2149388-2152618 chr19:2164096-2168510 chr19:2161138-2174962 chr19:2154455-2169953 chr19:2162573-2172275 chr19:2153839-2188314 chr19:2154124-2187326 chr19:2160421-2188542 chr19:2153999-2172372 chr19:2154511-2187651 chr19:2162124-2174662 chr19:2163345-2174238 chr19:2162534-2177270 chr19:2163290-2174646 chr19:2163024-2187823 chr19:2163034-2190261 chr19:2209992-2228315 chr19:2161284-2170043 chr19:2162462-2174342 chr19:2153494-2192345 chr19:2159673-2171923 chr19:2161341-2174626 chr19:2161346-2174695 chr19:2149414-2171025 chr19:2149536-2177317 chr19:2149451-2177370 chr19:2149432-2172132 chr19:2149515-2190054 chr19:2149473-2172687 chr19:2149384-2170266 chr19:2149483-2182888 chr19:2149174-2170175 chr19:2144594-2177302 chr19:2144054-2177487 chr19:2149190-2202999 chr19:2149112-2172575 chr19:2149549-2177016 chr19:2148449-2174007 chr19:2149522-2170636 chr19:2149518-2177537 chr19:2149534-2170014 chr19:2149534-2170014 chr19:2147867-2183633 chr19:2149482-2177625 chr19:2149276-2171899 chr19:2149414-2190694 chr19:2149380-2172387 chr19:2145000-2176695 chr19:2149404-2187294 chr19:2145505-2188692 chr19:2145931-2188705 chr19:2149073-2172188 chr19:2149545-2174936 chr19:2148049-2171559 chr19:2148264-2171699 chr19:2149472-2171597 chr19:2149445-2170014 chr19:2129022-2190371 chr19:2129137-2189673 chr19:2149264-2190590 chr19:2149450-2172009 chr19:2149738-2171446 chr19:2149417-2175818 |
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| Enhancer: |
chr19:2166440-2167850 chr19:2041200-2041830 chr19:2042520-2042600 chr19:2050950-2051090 chr19:2269740-2271380 chr19:2042660-2042760 chr19:2042870-2043120 chr19:2043200-2043500 chr19:2082000-2084060 chr19:2084800-2085170 chr19:2086150-2088590 chr19:2079140-2081340 chr19:2271530-2271780 chr19:2271950-2272730 chr19:2273490-2274630 chr19:2280940-2282080 chr19:2207680-2208930 chr19:2211840-2213530 chr19:2241350-2243380 chr19:2427040-2427250 chr19:2427320-2427410 chr19:2476400-2476530 chr19:2476630-2477020 chr19:2341010-2343200 chr19:2252800-2252910 chr19:2253000-2253610 chr19:2253790-2254180 chr19:1825940-1826870 chr19:2039860-2040130 chr19:2040170-2041030 chr19:2252070-2252240 chr19:2255340-2256380 chr19:2272820-2272970 chr19:2477250-2477480 chr19:2333620-2334600 chr19:2345330-2346890 chr19:1965860-1967730 chr19:1872320-1874420 chr19:1908960-1910680 chr19:2114300-2114740 chr19:2164260-2166420 chr19:2013010-2015290 chr19:2004990-2005540 chr19:2042030-2042430 chr19:2119760-2120580 chr19:2127200-2128660 chr19:2128870-2129080 chr19:2129160-2129310 chr19:2137810-2138610 chr19:2129460-2130400 chr19:1754850-1756620 chr19:2301940-2304060 chr19:2545680-2548040 chr19:1810680-1811480 chr19:1880140-1880890 chr19:1881050-1881230 chr19:1974250-1975710 chr19:1977010-1978300 chr19:2213640-2213840 chr19:2213990-2214460 chr19:2276490-2278140 chr19:2208970-2210140 chr19:2214600-2216270 chr19:2422250-2424080 chr19:2425490-2425620 chr19:2191240-2192770 chr19:2243540-2244110 chr19:2337620-2338750 chr19:2007160-2007620 chr19:2026840-2027240 chr19:2027400-2029900 chr19:2060460-2062830 chr19:2085330-2086020 chr19:2533250-2534680 chr19:2046280-2046360 chr19:2046470-2046600 chr19:2223490-2225380 chr19:2416810-2417990 chr19:2073420-2075920 chr19:2172570-2174550 chr19:2229140-2229440 chr19:2229500-2229780 chr19:2560960-2563040 chr19:2594210-2595120 chr19:2595210-2597700 chr19:2788360-2790410 chr19:2454180-2456660 chr19:2425270-2425350 chr19:2254300-2254440 chr19:1986650-1986820 chr19:1986980-1987160 chr19:1987250-1987490 chr19:1987690-1990000 chr19:1990200-1990710 chr19:1990820-1993010 chr19:1993180-1993880 chr19:2123400-2123820 chr19:2250760-2250840 chr19:2251010-2251090 chr19:2254480-2255200 chr19:2409300-2410250 chr19:2414020-2415660 chr19:2415840-2416530 chr19:2424260-2424990 chr19:2220220-2221970 chr19:2517730-2519100 chr19:2649600-2651350 chr19:2790630-2792350 chr19:2810770-2811590 chr19:2811730-2813110 chr19:2684980-2686980 chr19:2336400-2337440 chr19:2492550-2493240 chr19:2502930-2504890 chr19:2528180-2530540 chr19:2532080-2533190 chr19:2769090-2771260 chr19:2506200-2508360 chr19:2371650-2373310 chr19:2373960-2375910 chr19:1690200-1692230 chr19:1796260-1796700 chr19:2112970-2113330 chr19:2497860-2499600 chr19:2499740-2501400 chr19:2113410-2114120 chr19:1772900-1775150 chr19:1969960-1971740 chr19:2203420-2204970 chr19:2205240-2206100 chr19:2393240-2395580 chr19:2617820-2620070 chr19:2587000-2589300 chr19:1508110-1508440 chr19:2298760-2299410 chr19:2516540-2517260 chr19:2175530-2177630 chr19:1978340-1978440 chr19:1978510-1978600 chr19:1978750-1978850 chr19:1979090-1979160 chr19:1979250-1979310 chr19:2108770-2109080 chr19:1927430-1928360 chr19:2411460-2413690 chr19:2496930-2497560 chr19:1997460-1999640 chr19:1453610-1455140 chr19:1508570-1510140 chr19:1511160-1512960 chr19:1524250-1525300 chr19:1565000-1567460 chr19:2103230-2104660 chr19:2359950-2362090 chr19:2535510-2536940 chr19:2616550-2617620 chr19:2694300-2696280 chr19:2696490-2696890 chr19:2700370-2702640 chr19:2738220-2739940 chr19:2820120-2821820 chr19:2355100-2356830 chr19:2478260-2480660 chr19:1823780-1824100 chr19:2108490-2108680 chr19:2109210-2109580 chr19:2114820-2115210 chr19:2115420-2115530 chr19:2117370-2117870 chr19:2118270-2118500 chr19:2280600-2280840 |
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| Promoter: |
chr19:2161933-2165933 |
ChIP-seq based regulatory details of DOT1L
| Sample ID | CR | Biosample type | Biosample term name | File accession | Experiment accession | Source |
|---|
Downstream target genes of DOT1L
Upstream regulatory details of DOT1L
Protein-protein interaction of DOT1L
Annotation of DOT1L
TCGA cancer survival map of DOT1L
Other information of DOT1L