CR overview
CR: SIRT6
Accession: Q8N6T7
Protein names: NAD-dependent protein deacetylase sirtuin-6
Function type: Histone Modifier
Histone type: Eraser
Methytor type: Unkown
Aliases: sirtuin family;Histone deacetylases;HDAC
PMID: 31437090 33353368 28871079
Disease: 2
Go term: 38
Pathway: 3
Hallmark: 1
Super Enhancer:

Enhancer:

chr19:4247170-4249220 chr19:4173050-4174100 chr19:4283240-4284770 chr19:4327380-4328670 chr19:4337210-4338520 chr19:3784880-3785060 chr19:3785280-3786160 chr19:4325540-4326930 chr19:4327000-4327120 chr19:4327220-4327310 chr19:4328810-4329950 chr19:4343990-4345210 chr19:4430640-4431940 chr19:4432200-4433060 chr19:4558500-4559540 chr19:4606220-4608320 chr19:3624160-3626590 chr19:4196720-4199180 chr19:4352580-4352890 chr19:3969830-3970910 chr19:4363470-4363710 chr19:4363880-4364080 chr19:4361790-4362320 chr19:4534110-4535170 chr19:3982420-3982500 chr19:4208790-4210050 chr19:4210140-4210260 chr19:4211510-4212470 chr19:4212510-4212590 chr19:4222790-4224120 chr19:4231320-4233120 chr19:4233300-4234660 chr19:4236330-4236930 chr19:4556100-4556960 chr19:4210370-4211410 chr19:4153770-4154890 chr19:4362380-4362600 chr19:4362730-4363360 chr19:4298340-4299590 chr19:4213620-4215920 chr19:4229620-4231180 chr19:3618990-3619070 chr19:4240380-4242110 chr19:4266540-4267620 chr19:4525090-4525640 chr19:4558160-4558340 chr19:4121620-4123780 chr19:4357580-4358070 chr19:4366990-4368850 chr19:3822200-3823240 chr19:3976750-3977210 chr19:3977610-3977810 chr19:3979440-3979800 chr19:3980060-3980510 chr19:3981450-3981940 chr19:4295980-4297710 chr19:4267770-4268580 chr19:4284900-4285490 chr19:3977350-3977420 chr19:3978170-3979320 chr19:3980710-3980830 chr19:4355170-4357240 chr19:4357420-4357510 chr19:4358170-4359150 chr19:4359250-4359910 chr19:4360080-4360360 chr19:4364220-4365470 chr19:4365620-4366490 chr19:4366570-4366920 chr19:4446200-4446270 chr19:4446410-4446490 chr19:4446720-4446830 chr19:4446920-4447540 chr19:4447620-4448310 chr19:4452490-4453450 chr19:4453520-4453920 chr19:4454090-4455210 chr19:4491830-4493690 chr19:4508970-4510450 chr19:3980980-3981330 chr19:4668650-4670170 chr19:3825410-3827460 chr19:3852610-3853400 chr19:3999580-4000330 chr19:4158830-4159160 chr19:4220760-4221540 chr19:4286480-4288230 chr19:4288360-4288950 chr19:4310590-4311830 chr19:4515500-4516620 chr19:4516690-4517560 chr19:4555580-4555990 chr19:4557030-4557170 chr19:4557240-4558030 chr19:3784450-3784820 chr19:4310290-4310470 chr19:4531840-4534020 chr19:4308920-4310260 chr19:3345850-3347490 chr19:3379650-3381700 chr19:3403140-3405580 chr19:3405810-3407060 chr19:3434400-3435080 chr19:3513220-3515500 chr19:4102450-4104020 chr19:4104070-4106460 chr19:4120500-4121560 chr19:4388120-4389850 chr19:4425230-4426740 chr19:4390310-4392400 chr19:4504960-4507450 chr19:4695570-4697560 chr19:4697660-4698070 chr19:4704320-4705860 chr19:4714350-4716520 chr19:3724940-3726780 chr19:4018990-4019220 chr19:4019400-4019970 chr19:4023160-4024030 chr19:4049220-4050940 chr19:4175380-4175670 chr19:4429790-4430260 chr19:3273920-3275850 chr19:3478480-3478810 chr19:3982050-3982240 chr19:4393700-4395780 chr19:4097340-4099190 chr19:3827650-3828990 chr19:3952890-3954980 chr19:3957030-3958450 chr19:4592470-4594010 chr19:4087880-4090310 chr19:3807270-3808860 chr19:3837230-3839220 chr19:4016390-4016660 chr19:3816840-3819040 chr19:4014020-4016220 chr19:4095450-4097270 chr19:4409760-4411620 chr19:3844610-3845110 chr19:4038070-4039930 chr19:4042040-4043800 chr19:4081340-4082590 chr19:4085510-4087600 chr19:4094490-4095380 chr19:4513720-4514470 chr19:4280360-4280600 chr19:3907920-3908260 chr19:3908370-3909480 chr19:3917770-3918800

Promoter:

chr19:4180566-4184566

 ChIP-seq based regulatory details of SIRT6
Sample ID CR Biosample type Biosample term name File accession Experiment accession Source
CR_01_0034 SIRT6 cell line K562 ENCFF000CCK ENCSR000AUB Encode
CR_01_0682 SIRT6 cell line H1-hESC ENCFF000BAG ENCSR000AUS Encode
CR_01_0806 SIRT6 cell line K562 ENCFF000YZS ENCSR000DOH Encode
CR_01_0807 SIRT6 cell line K562 ENCFF000YZT ENCSR000DOH Encode
 Downstream target genes of SIRT6
 Protein-protein interaction of SIRT6
 Annotation of SIRT6
 TCGA cancer survival map of SIRT6


Calculate the hazards ratio based on Cox PH Model.
Add the 95% CI as dotted line.
Reset Add The plot axis-x order will follow the list.


Calculate the hazards ratio based on Cox PH Model.
We use log2(TPM + 1) for log-scale.
All Add
Reset The plot is based on the datasets of list.