| UBA52 |
Activated NOTCH1 Transmits Signal to the Nucleus |
reactome |
30 |
195 |
| UBA52 |
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
reactome |
18 |
122 |
| UBA52 |
Activation of NF-kappaB in B cells |
reactome |
66 |
1552 |
| UBA52 |
Amyloid fiber formation |
reactome |
99 |
1690 |
| UBA52 |
Antigen processing: Ubiquitination & Proteasome degradation |
reactome |
260 |
9688 |
| UBA52 |
APC-Cdc20 mediated degradation of Nek2A |
reactome |
25 |
301 |
| UBA52 |
APC/C:Cdc20 mediated degradation of Cyclin B |
reactome |
23 |
254 |
| UBA52 |
APC/C:Cdc20 mediated degradation of Securin |
reactome |
66 |
2102 |
| UBA52 |
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
reactome |
71 |
2321 |
| UBA52 |
Assembly Of The HIV Virion |
reactome |
5 |
10 |
| UBA52 |
Association of licensing factors with the pre-replicative complex |
reactome |
15 |
58 |
| UBA52 |
Asymmetric localization of PCP proteins |
reactome |
63 |
1276 |
| UBA52 |
AUF1 (hnRNP D0) binds and destabilizes mRNA |
reactome |
54 |
1209 |
| UBA52 |
Autodegradation of Cdh1 by Cdh1:APC/C |
reactome |
62 |
1892 |
| UBA52 |
Autodegradation of the E3 ubiquitin ligase COP1 |
reactome |
51 |
1160 |
| UBA52 |
Budding and maturation of HIV virion |
reactome |
25 |
300 |
| UBA52 |
Cdc20:Phospho-APC/C mediated degradation of Cyclin A |
reactome |
71 |
2480 |
| UBA52 |
CDK-mediated phosphorylation and removal of Cdc6 |
reactome |
50 |
1181 |
| UBA52 |
CDT1 association with the CDC6:ORC:origin complex |
reactome |
58 |
1191 |
| UBA52 |
Circadian Clock |
reactome |
49 |
389 |
| UBA52 |
CLEC7A (Dectin-1) signaling |
reactome |
78 |
1727 |
| UBA52 |
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants |
reactome |
19 |
141 |
| UBA52 |
Constitutive Signaling by NOTCH1 HD Domain Mutants |
reactome |
15 |
90 |
| UBA52 |
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants |
reactome |
57 |
500 |
| UBA52 |
Constitutive Signaling by NOTCH1 PEST Domain Mutants |
reactome |
57 |
500 |
| UBA52 |
Cyclin D associated events in G1 |
reactome |
38 |
366 |
| UBA52 |
Deactivation of the beta-catenin transactivating complex |
reactome |
42 |
236 |
| UBA52 |
Dectin-1 mediated noncanonical NF-kB signaling |
reactome |
61 |
1526 |
| UBA52 |
Degradation of AXIN |
reactome |
54 |
1370 |
| UBA52 |
Degradation of beta-catenin by the destruction complex |
reactome |
67 |
2178 |
| UBA52 |
Degradation of DVL |
reactome |
56 |
1335 |
| UBA52 |
Degradation of GLI1 by the proteasome |
reactome |
59 |
1494 |
| UBA52 |
Degradation of GLI2 by the proteasome |
reactome |
59 |
1505 |
| UBA52 |
DNA Damage Recognition in GG-NER |
reactome |
38 |
547 |
| UBA52 |
Downregulation of ERBB2:ERBB3 signaling |
reactome |
13 |
59 |
| UBA52 |
Downregulation of ERBB4 signaling |
reactome |
8 |
26 |
| UBA52 |
Downregulation of SMAD2/3:SMAD4 transcriptional activity |
reactome |
23 |
145 |
| UBA52 |
Downregulation of TGF-beta receptor signaling |
reactome |
26 |
168 |
| UBA52 |
Downstream TCR signaling |
reactome |
101 |
1991 |
| UBA52 |
Dual Incision in GG-NER |
reactome |
39 |
736 |
| UBA52 |
Dual incision in TC-NER |
reactome |
63 |
1948 |
| UBA52 |
EGFR downregulation |
reactome |
27 |
255 |
| UBA52 |
Endosomal Sorting Complex Required For Transport (ESCRT) |
reactome |
28 |
285 |
| UBA52 |
ER-Phagosome pathway |
reactome |
65 |
1264 |
| UBA52 |
Eukaryotic Translation Termination |
reactome |
90 |
3742 |
| UBA52 |
Fanconi Anemia Pathway |
reactome |
39 |
627 |
| UBA52 |
FCERI mediated NF-kB activation |
reactome |
88 |
1785 |
| UBA52 |
Formation of a pool of free 40S subunits |
reactome |
99 |
4263 |
| UBA52 |
Formation of Incision Complex in GG-NER |
reactome |
43 |
698 |
| UBA52 |
Formation of TC-NER Pre-Incision Complex |
reactome |
53 |
1056 |
| UBA52 |
G2/M Checkpoints |
reactome |
50 |
1193 |
| UBA52 |
Gap-filling DNA repair synthesis and ligation in GG-NER |
reactome |
23 |
246 |
| UBA52 |
Gap-filling DNA repair synthesis and ligation in TC-NER |
reactome |
62 |
1884 |
| UBA52 |
GLI3 is processed to GLI3R by the proteasome |
reactome |
59 |
1548 |
| UBA52 |
Glycogen synthesis |
reactome |
15 |
43 |
| UBA52 |
GTP hydrolysis and joining of the 60S ribosomal subunit |
reactome |
110 |
4945 |
| UBA52 |
HDR through Homologous Recombination (HRR) |
reactome |
46 |
1019 |
| UBA52 |
Hedgehog on state |
reactome |
72 |
1642 |
| UBA52 |
Hedgehog ligand biogenesis |
reactome |
59 |
1198 |
| UBA52 |
Hh mutants that dont undergo autocatalytic processing are degraded by ERAD |
reactome |
55 |
1173 |
| UBA52 |
IKK complex recruitment mediated by RIP1 |
reactome |
24 |
234 |
| UBA52 |
IRAK2 mediated activation of TAK1 complex |
reactome |
10 |
32 |
| UBA52 |
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
reactome |
10 |
32 |
| UBA52 |
ISG15 antiviral mechanism |
reactome |
73 |
887 |
| UBA52 |
L13a-mediated translational silencing of Ceruloplasmin expression |
reactome |
109 |
4909 |
| UBA52 |
Major pathway of rRNA processing in the nucleolus |
reactome |
168 |
6527 |
| UBA52 |
MAP3K8 (TPL2)-dependent MAPK1/3 activation |
reactome |
16 |
79 |
| UBA52 |
MAPK6/MAPK4 signaling |
reactome |
90 |
1485 |
| UBA52 |
Membrane binding and targetting of GAG proteins |
reactome |
11 |
45 |
| UBA52 |
Myoclonic epilepsy of Lafora |
reactome |
10 |
21 |
| UBA52 |
Negative regulation of FGFR1 signaling |
reactome |
26 |
303 |
| UBA52 |
Negative regulation of FGFR2 signaling |
reactome |
27 |
343 |
| UBA52 |
Negative regulation of FGFR3 signaling |
reactome |
22 |
219 |
| UBA52 |
Negative regulation of FGFR4 signaling |
reactome |
24 |
268 |
| UBA52 |
Negative regulation of MAPK pathway |
reactome |
38 |
287 |
| UBA52 |
Negative regulators of RIG-I/MDA5 signaling |
reactome |
34 |
215 |
| UBA52 |
NF-kB is activated and signals survival |
reactome |
13 |
61 |
| UBA52 |
NIK-->noncanonical NF-kB signaling |
reactome |
58 |
1471 |
| UBA52 |
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
reactome |
109 |
5865 |
| UBA52 |
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) |
reactome |
92 |
4181 |
| UBA52 |
NOTCH1 Intracellular Domain Regulates Transcription |
reactome |
47 |
463 |
| UBA52 |
NOTCH2 Activation and Transmission of Signal to the Nucleus |
reactome |
21 |
107 |
| UBA52 |
NRIF signals cell death from the nucleus |
reactome |
15 |
62 |
| UBA52 |
Oncogene Induced Senescence |
reactome |
30 |
146 |
| UBA52 |
Orc1 removal from chromatin |
reactome |
70 |
1618 |
| UBA52 |
Oxidative Stress Induced Senescence |
reactome |
120 |
3580 |
| UBA52 |
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha |
reactome |
18 |
112 |
| UBA52 |
p75NTR recruits signalling complexes |
reactome |
13 |
53 |
| UBA52 |
Peptide chain elongation |
reactome |
87 |
3718 |
| UBA52 |
Pink/Parkin Mediated Mitophagy |
reactome |
22 |
113 |
| UBA52 |
Processing of DNA double-strand break ends |
reactome |
98 |
2697 |
| UBA52 |
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 |
reactome |
9 |
16 |
| UBA52 |
Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
reactome |
14 |
81 |
| UBA52 |
Recognition of DNA damage by PCNA-containing replication complex |
reactome |
28 |
338 |
| UBA52 |
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
reactome |
75 |
2122 |
| UBA52 |
Regulation of activated PAK-2p34 by proteasome mediated degradation |
reactome |
49 |
1133 |
| UBA52 |
Regulation of FZD by ubiquitination |
reactome |
21 |
80 |
| UBA52 |
Regulation of innate immune responses to cytosolic DNA |
reactome |
14 |
43 |
| UBA52 |
Regulation of PLK1 Activity at G2/M Transition |
reactome |
87 |
2819 |
| UBA52 |
Regulation of RAS by GAPs |
reactome |
67 |
1453 |
| UBA52 |
Regulation of TNFR1 signaling |
reactome |
31 |
297 |
| UBA52 |
Regulation of TP53 Activity through Methylation |
reactome |
19 |
77 |
| UBA52 |
Regulation of TP53 Activity through Phosphorylation |
reactome |
89 |
1144 |
| UBA52 |
Regulation of TP53 Degradation |
reactome |
35 |
257 |
| UBA52 |
SCF-beta-TrCP mediated degradation of Emi1 |
reactome |
54 |
1387 |
| UBA52 |
SCF(Skp2)-mediated degradation of p27/p21 |
reactome |
59 |
1486 |
| UBA52 |
Selenocysteine synthesis |
reactome |
90 |
3738 |
| UBA52 |
Senescence-Associated Secretory Phenotype (SASP) |
reactome |
108 |
2712 |
| UBA52 |
Separation of Sister Chromatids |
reactome |
163 |
7519 |
| UBA52 |
Signaling by ERBB2 |
reactome |
25 |
198 |
| UBA52 |
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
reactome |
32 |
197 |
| UBA52 |
Spry regulation of FGF signaling |
reactome |
16 |
90 |
| UBA52 |
SRP-dependent cotranslational protein targeting to membrane |
reactome |
110 |
5855 |
| UBA52 |
Stabilization of p53 |
reactome |
9 |
35 |
| UBA52 |
Stimuli-sensing channels |
reactome |
77 |
397 |
| UBA52 |
TCF dependent signaling in response to WNT |
reactome |
31 |
189 |
| UBA52 |
Termination of translesion DNA synthesis |
reactome |
30 |
338 |
| UBA52 |
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
reactome |
16 |
116 |
| UBA52 |
The role of GTSE1 in G2/M progression after G2 checkpoint |
reactome |
59 |
1330 |
| UBA52 |
TRAF6 Mediated Induction of proinflammatory cytokines |
reactome |
5 |
10 |
| UBA52 |
TRAF6 mediated induction of TAK1 complex |
reactome |
16 |
101 |
| UBA52 |
Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
reactome |
44 |
946 |
| UBA52 |
Translesion Synthesis by POLH |
reactome |
19 |
158 |
| UBA52 |
Translesion synthesis by POLI |
reactome |
17 |
136 |
| UBA52 |
Translesion synthesis by POLK |
reactome |
17 |
136 |
| UBA52 |
Translesion synthesis by REV1 |
reactome |
16 |
120 |
| UBA52 |
Ubiquitin-dependent degradation of Cyclin D1 |
reactome |
50 |
1137 |
| UBA52 |
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A |
reactome |
52 |
1146 |
| UBA52 |
Vif-mediated degradation of APOBEC3G |
reactome |
53 |
1334 |
| UBA52 |
Viral mRNA Translation |
reactome |
87 |
3567 |
| UBA52 |
Vpu mediated degradation of CD4 |
reactome |
51 |
1231 |