T(co)F Overview
T(co)F: Suz12
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: Others
T(co)F Superclass: TcoF-DB_TcoF
Biosample Name: Alveolar macrophage
Tissue Type: Lung
Biosample Type: Primary cell
# of Control: 4
# of Treat: 5
Data Source: GEO
Profile ID: GSE176115
Platform: GPL19057
Pubmed ID: 34533976

Suz12- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Suz12
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Suz12

Upstream Pathway Annotation of Suz12
T(co)F Pathway Name Source Gene Number
Suz12 EPIGENETIC_REGULATION_OF_GENE_EXPRESSION REACTOME 112
Suz12 PRC2_METHYLATES_HISTONES_AND_DNA REACTOME 81
Suz12 GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Suz12 OXIDATIVE_STRESS_INDUCED_SENESCENCE REACTOME 38
Suz12 CELLULAR_SENESCENCE REACTOME 95
Suz12 SUMOYLATION REACTOME 165
Suz12 PKMTS_METHYLATE_HISTONE_LYSINES REACTOME 67
Suz12 CHROMATIN_MODIFYING_ENZYMES REACTOME 205
Suz12 METABOLISM_OF_PROTEINS REACTOME 1657
Suz12 SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS REACTOME 65
Suz12 POST_TRANSLATIONAL_PROTEIN_MODIFICATION REACTOME 1310
Suz12 PTEN_REGULATION REACTOME 113
Suz12 GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Suz12 REGULATION_OF_PTEN_GENE_TRANSCRIPTION REACTOME 42
Suz12 TRANSCRIPTIONAL_REGULATION_BY_E2F6 REACTOME 23
Suz12 CELLULAR_RESPONSES_TO_STIMULI REACTOME 454
Suz12 INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS REACTOME 260
Suz12 MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY WP 290
Target Gene Expression Analysis
Expression Atlas of Suz12