T(co)F Overview
T(co)F: Usp7
Species: Mus musculus
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: TcoF-DB_TcoF
Biosample Name: ES cells
Tissue Type: Embryo
Biosample Type: Cell line
# of Control: 2
# of Treat: 4
Data Source: GEO
Profile ID: GSE149341
Platform: GPL17021
Pubmed ID: -

Usp7- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Usp7
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Usp7

Upstream Pathway Annotation of Usp7
T(co)F Pathway Name Source Gene Number
Usp7 GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Usp7 TRANSCRIPTIONAL_REGULATION_BY_TP53 REACTOME 301
Usp7 METABOLISM_OF_PROTEINS REACTOME 1657
Usp7 REGULATION_OF_TP53_ACTIVITY REACTOME 155
Usp7 DEUBIQUITINATION REACTOME 254
Usp7 UB_SPECIFIC_PROCESSING_PROTEASES REACTOME 184
Usp7 NUCLEOTIDE_EXCISION_REPAIR REACTOME 108
Usp7 POST_TRANSLATIONAL_PROTEIN_MODIFICATION REACTOME 1310
Usp7 FORMATION_OF_TC_NER_PRE_INCISION_COMPLEX REACTOME 53
Usp7 TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR_T REACTOME 76
Usp7 DUAL_INCISION_IN_TC_NER REACTOME 64
Usp7 REGULATION_OF_TP53_DEGRADATION REACTOME 36
Usp7 PTEN_REGULATION REACTOME 113
Usp7 DNA_REPAIR REACTOME 299
Usp7 GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Usp7 PROTEIN_UBIQUITINATION REACTOME 74
Usp7 SYNTHESIS_OF_ACTIVE_UBIQUITIN_ROLES_OF_E1_AND_E2_E REACTOME 31
Usp7 REGULATION_OF_PTEN_LOCALIZATION REACTOME 10
Usp7 INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS REACTOME 260
Usp7 MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY WP 290
Target Gene Expression Analysis
Expression Atlas of Usp7