T(co)F Overview
T(co)F: Dnmt1
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: CXXC zinc finger factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: mature Pvergic cortical interneurons
Tissue Type: Cortex
Biosample Type: Tissue
# of Control: 4
# of Treat: 4
Data Source: GEO
Profile ID: GSE145025
Platform: GPL17021
Pubmed ID: 32147726

Dnmt1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Dnmt1
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Dnmt1
Upstream Pathway Annotation of Dnmt1
T(co)F Pathway Name Source Gene Number
Dnmt1 EPIGENETIC_REGULATION_OF_GENE_EXPRESSION REACTOME 112
Dnmt1 PRC2_METHYLATES_HISTONES_AND_DNA REACTOME 81
Dnmt1 SUMOYLATION REACTOME 165
Dnmt1 METABOLISM_OF_PROTEINS REACTOME 1657
Dnmt1 POST_TRANSLATIONAL_PROTEIN_MODIFICATION REACTOME 1310
Dnmt1 GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Dnmt1 GLUTATHIONE_AND_ONECARBON_METABOLISM WP 31
Dnmt1 ONECARBON_METABOLISM WP 29
Dnmt1 MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY WP 290
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Dnmt1
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)