T(co)F Overview
T(co)F: Ctnnb1
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: Casein
T(co)F Superclass: Co-activator/repressors
Biosample Name: MGE cells
Tissue Type: Embryo
Biosample Type: Cell line
# of Control: 4
# of Treat: 5
Data Source: GEO
Profile ID: GSE130320
Platform: GPL17021
Pubmed ID: 34460072

Ctnnb1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Ctnnb1
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Ctnnb1
Upstream Pathway Annotation of Ctnnb1
T(co)F Pathway Name Source Gene Number
Ctnnb1 CELL2CELL_PATHWAY BIOCARTA 9
Ctnnb1 GSK3_PATHWAY BIOCARTA 21
Ctnnb1 PITX2_PATHWAY BIOCARTA 15
Ctnnb1 PS1_PATHWAY BIOCARTA 14
Ctnnb1 TFF_PATHWAY BIOCARTA 25
Ctnnb1 WNT_PATHWAY BIOCARTA 23
Ctnnb1 APOPTOSIS REACTOME 103
Ctnnb1 APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS REACTOME 37
Ctnnb1 DEVELOPMENTAL_BIOLOGY REACTOME 484
Ctnnb1 CELL_CELL_COMMUNICATION REACTOME 88
Ctnnb1 INNATE_IMMUNE_SYSTEM REACTOME 1087
Ctnnb1 IMMUNE_SYSTEM REACTOME 1775
Ctnnb1 CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA REACTOME 33
Ctnnb1 SIGNALING_BY_VEGF REACTOME 100
Ctnnb1 DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COM REACTOME 80
Ctnnb1 RHO_GTPASE_EFFECTORS REACTOME 245
Ctnnb1 SIGNALING_BY_WNT REACTOME 235
Ctnnb1 BETA_CATENIN_PHOSPHORYLATION_CASCADE REACTOME 17
Ctnnb1 TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT REACTOME 154
Ctnnb1 FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_ REACTOME 23
Ctnnb1 GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Ctnnb1 APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS REACTOME 10
Ctnnb1 DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_C REACTOME 32
Ctnnb1 BETA_CATENIN_INDEPENDENT_WNT_SIGNALING REACTOME 127
Ctnnb1 CA2_PATHWAY REACTOME 47
Ctnnb1 ADHERENS_JUNCTIONS_INTERACTIONS REACTOME 32
Ctnnb1 CELL_CELL_JUNCTION_ORGANIZATION REACTOME 40
Ctnnb1 CELL_JUNCTION_ORGANIZATION REACTOME 65
Ctnnb1 DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUIT REACTOME 30
Ctnnb1 VEGFR2_MEDIATED_VASCULAR_PERMEABILITY REACTOME 29
Ctnnb1 MYOGENESIS REACTOME 25
Ctnnb1 PROGRAMMED_CELL_DEATH REACTOME 135
Ctnnb1 RHO_GTPASES_ACTIVATE_IQGAPS REACTOME 29
Ctnnb1 GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Ctnnb1 APOPTOTIC_EXECUTION_PHASE REACTOME 49
Ctnnb1 TRANSCRIPTIONAL_REGULATION_BY_VENTX REACTOME 6
Ctnnb1 TRANSCRIPTIONAL_REGULATION_BY_RUNX3 REACTOME 78
Ctnnb1 RUNX3_REGULATES_WNT_SIGNALING REACTOME 6
Ctnnb1 SIGNALING_BY_RECEPTOR_TYROSINE_KINASES REACTOME 401
Ctnnb1 SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3 REACTOME 620
Ctnnb1 ID_SIGNALING_PATHWAY WP 50
Ctnnb1 WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY WP 97
Ctnnb1 ESC_PLURIPOTENCY_PATHWAYS WP 116
Ctnnb1 WNT_SIGNALING_IN_KIDNEY_DISEASE WP 43
Ctnnb1 TGFBETA_SIGNALING_PATHWAY WP 52
Ctnnb1 HEART_DEVELOPMENT WP 46
Ctnnb1 GDNFRET_SIGNALING_AXIS WP 22
Ctnnb1 WNT_SIGNALING_PATHWAY_WP403 WP 60
Ctnnb1 PTF1A_RELATED_REGULATORY_PATHWAY WP 13
Ctnnb1 MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY WP 100
Ctnnb1 PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS WP 71
Ctnnb1 NEURAL_CREST_DIFFERENTIATION WP 99
Ctnnb1 IL5_SIGNALING_PATHWAY WP 68
Ctnnb1 ADIPOGENESIS_GENES WP 132
Ctnnb1 WNT_SIGNALING_PATHWAY_WP539 WP 108
Ctnnb1 MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY WP 290
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Ctnnb1
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)