T(co)F Overview
T(co)F: Hipk2
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: HIPK
T(co)F Superclass: Other Cofactors
Biosample Name: cardiac tissue
Tissue Type: Heart
Biosample Type: Tissue
# of Control: 5
# of Treat: 5
Data Source: GEO
Profile ID: GSE169429
Platform: GPL21163
Pubmed ID: 36182775

Hipk2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Hipk2
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Hipk2

Upstream Pathway Annotation of Hipk2
T(co)F Pathway Name Source Gene Number
Hipk2 GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Hipk2 SUMOYLATION REACTOME 165
Hipk2 TRANSCRIPTIONAL_REGULATION_BY_TP53 REACTOME 301
Hipk2 SUMOYLATION_OF_TRANSCRIPTION_COFACTORS REACTOME 38
Hipk2 METABOLISM_OF_PROTEINS REACTOME 1657
Hipk2 REGULATION_OF_TP53_ACTIVITY REACTOME 155
Hipk2 POST_TRANSLATIONAL_PROTEIN_MODIFICATION REACTOME 1310
Hipk2 REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATIO REACTOME 91
Hipk2 GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Hipk2 TRANSCRIPTIONAL_REGULATION_BY_RUNX1 REACTOME 198
Hipk2 RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFE REACTOME 35
Hipk2 TRANSCRIPTIONAL_REGULATION_BY_MECP2 REACTOME 5
Hipk2 WNT_SIGNALING_PATHWAY_WP539 WP 108
Hipk2 MIR222_IN_EXERCISEINDUCED_CARDIAC_GROWTH WP 5
Target Gene Expression Analysis
Expression Atlas of Hipk2