T(co)F Overview
T(co)F: Smad1
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: SMAD/NF-1 DNA-binding domain factors
T(co)F Superclass: beta-Hairpin exposed by an alpha/beta-scaffold
Biosample Name: Lung left lobe
Tissue Type: Lung
Biosample Type: Tissue
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE26502
Platform: GPL1261
Pubmed ID: 21270055

Smad1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Smad1
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Smad1

Upstream Pathway Annotation of Smad1
T(co)F Pathway Name Source Gene Number
Smad1 CTCF_PATHWAY BIOCARTA 24
Smad1 SIGNALING_BY_BMP REACTOME 28
Smad1 GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Smad1 METABOLISM_OF_PROTEINS REACTOME 1657
Smad1 DEUBIQUITINATION REACTOME 254
Smad1 UB_SPECIFIC_PROCESSING_PROTEASES REACTOME 184
Smad1 POST_TRANSLATIONAL_PROTEIN_MODIFICATION REACTOME 1310
Smad1 GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Smad1 TRANSCRIPTIONAL_REGULATION_BY_RUNX2 REACTOME 63
Smad1 RUNX2_REGULATES_BONE_DEVELOPMENT REACTOME 6
Smad1 SIGNALING_BY_TGFB_FAMILY_MEMBERS REACTOME 101
Smad1 ID_SIGNALING_PATHWAY WP 50
Smad1 ESC_PLURIPOTENCY_PATHWAYS WP 116
Smad1 TGFBETA_SIGNALING_PATHWAY WP 52
Smad1 HEART_DEVELOPMENT WP 46
Smad1 BMP_SIGNALING_PATHWAY_IN_EYELID_DEVELOPMENT WP 20
Smad1 DELTANOTCH_SIGNALING_PATHWAY WP 82
Smad1 NEURAL_CREST_DIFFERENTIATION WP 99
Smad1 MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY WP 290
Target Gene Expression Analysis
Expression Atlas of Smad1