T(co)F Overview
T(co)F: Runx2
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: Runt domain factors
T(co)F Superclass: Immunoglobulin fold
Biosample Name: Embryonic humeri
Tissue Type: Humeri
Biosample Type: Tissue
# of Control: 2
# of Treat: 2
Data Source: GEO
Profile ID: GSE4911
Platform: GPL83
Pubmed ID: 16829211

Runx2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Runx2
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Runx2
Upstream Pathway Annotation of Runx2
T(co)F Pathway Name Source Gene Number
Runx2 GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Runx2 GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Runx2 TRANSCRIPTIONAL_REGULATION_BY_RUNX2 REACTOME 63
Runx2 RUNX2_REGULATES_BONE_DEVELOPMENT REACTOME 6
Runx2 ENDOCHONDRAL_OSSIFICATION WP 61
Runx2 TGFBETA_SIGNALING_PATHWAY WP 52
Runx2 WNT_SIGNALING_PATHWAY_WP539 WP 108
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Runx2
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)