T(co)F Overview
T(co)F: E2f4
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: Fork head / winged helix factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: Forebrain
Tissue Type: Brain
Biosample Type: Tissue
# of Control: 1
# of Treat: 1
Data Source: GEO
Profile ID: GSE10401
Platform: GPL339
Pubmed ID: -

E2f4- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of E2f4
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of E2f4
Upstream Pathway Annotation of E2f4
T(co)F Pathway Name Source Gene Number
E2f4 ETS_PATHWAY BIOCARTA 17
E2f4 G0_AND_EARLY_G1 REACTOME 17
E2f4 CELL_CYCLE REACTOME 601
E2f4 SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX REACTOME 74
E2f4 GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
E2f4 TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETE REACTOME 40
E2f4 SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIP REACTOME 26
E2f4 MITOTIC_G1_PHASE_AND_G1_S_TRANSITION REACTOME 130
E2f4 CYCLIN_D_ASSOCIATED_EVENTS_IN_G1 REACTOME 44
E2f4 GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
E2f4 SIGNALING_BY_TGFB_FAMILY_MEMBERS REACTOME 101
E2f4 G1_TO_S_CELL_CYCLE_CONTROL WP 60
E2f4 ADIPOGENESIS_GENES WP 132
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of E2f4
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)