T(co)F Overview
T(co)F: SNW1
Species: Homo sapiens
Knock-Method: CRISPR
T(co)F Class: Others
T(co)F Superclass: Other Cofactors
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR458FLK
Platform: -
Pubmed ID: 22955616

SNW1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of SNW1
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of SNW1
Upstream Pathway Annotation of SNW1
T(co)F Pathway Name Source Gene Number
SNW1 NICD traffics to nucleus Reactome 13
SNW1 Notch-HLH transcription pathway Reactome 13
SNW1 Hs_Notch_Signaling_Pathway_WP61_78592 WikiPathways 16
SNW1 Hs_RIG-I-like_Receptor_Signaling_WP3865_88186 WikiPathways 19
SNW1 Pre-NOTCH Transcription and Translation Reactome 29
SNW1 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome 32
SNW1 Notch signaling pathway KEGG 44
SNW1 NOTCH1 Intracellular Domain Regulates Transcription Reactome 47
SNW1 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome 57
SNW1 Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome 57
SNW1 Notch NetPath 76
SNW1 TGF_beta_Receptor NetPath 220
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of SNW1
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines