T(co)F Overview
T(co)F: SMARCA4
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: TcoF-DB_TF
Biosample Name: HCT116
Tissue Type: Colon
Biosample Type: Cell line
# of Control: 1
# of Treat: 2
Data Source: GEO
Profile ID: GSE143199
Platform: GPL21185
Pubmed ID: 33853662

SMARCA4- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of SMARCA4
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of SMARCA4
Upstream Pathway Annotation of SMARCA4
T(co)F Pathway Name Source Gene Number
SMARCA4 BMP signaling in Drosophila ( BMP signaling in Drosophila ) INOH 7
SMARCA4 BMP signaling in Drosophila (dorsal midline) ( BMP signaling in Drosophila ) INOH 7
SMARCA4 BMP signaling in Drosophila (dorsolateral) ( BMP signaling in Drosophila ) INOH 7
SMARCA4 Validated nuclear estrogen receptor beta network PID 15
SMARCA4 BMP signaling pathway ( TGF-beta_BMP Diagram(MolecularVariation) ) INOH 34
SMARCA4 Signaling with Wnt (Canonical) ( C. elegans endoderm induction Wnt signaling pathway Diagram ) INOH 47
SMARCA4 Signaling with Wnt (Canonical) ( Canonical Wnt signaling pathway Diagram ) INOH 47
SMARCA4 Signaling with Wnt (Canonical) ( Drosophila Wingless/Wnt signaling pathway Diagram ) INOH 47
SMARCA4 Signaling with Wnt (Canonical) ( Mammalian Wnt signaling pathway Diagram ) INOH 47
SMARCA4 Signaling with Wnt (Canonical) ( Xenopus axis formation Wnt signaling pathway Diagram ) INOH 47
SMARCA4 Signaling with Wnt (Mammal) ( Mammalian Wnt signaling pathway Diagram ) INOH 47
SMARCA4 TGF-beta_super_family_signaling_pathway(canonical) ( TGF-beta_BMP Diagram(MolecularVariation) ) INOH 51
SMARCA4 Regulation of retinoblastoma protein PID 67
SMARCA4 RMTs methylate histone arginines Reactome 75
SMARCA4 Regulation of nuclear beta catenin signaling and target gene transcription PID 80
SMARCA4 RANKL NetPath 84
SMARCA4 Glucocorticoid receptor regulatory network PID 85
SMARCA4 Formation of the beta-catenin:TCF transactivating complex Reactome 88
SMARCA4 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 WikiPathways 122
SMARCA4 Direct p53 effectors PID 141
SMARCA4 Wnt signaling pathway PANTHER 250
SMARCA4 TNFalpha NetPath 274
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of SMARCA4
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines