T(co)F Overview
T(co)F: SP100
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: SAND domain factors
T(co)F Superclass: alpha-Helices exposed by beta-structures
Biosample Name: MCF7
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 3
# of Treat: 1
Data Source: GEO
Profile ID: GSE31912
Platform: GPL570
Pubmed ID: 22536322

SP100- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of SP100
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of SP100
Upstream Pathway Annotation of SP100
T(co)F Pathway Name Source Gene Number
SP100 SUMOylation of DNA damage response and repair proteins Reactome 76
SP100 Interferon gamma signaling Reactome 88
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of SP100
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines