| T(co)F: | MITF |
| Species: | Homo sapiens |
| Knock-Method: | siRNA |
| T(co)F Class: | Basic helix-loop-helix factors (bHLH) |
| T(co)F Superclass: | Basic domains |
| Biosample Name: | Ma-Mel-15 |
| Tissue Type: | Skin |
| Biosample Type: | Cell line |
| # of Control: | 4 | # of Treat: | 4 |
| Data Source: | GEO |
| Profile ID: | GSE71886 |
| Platform: | GPL10558 |
| Pubmed ID: | 26530832 |
#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines
| Target Gene | T(co)F | Mean
Expr. of
Control
|
Mean
Expr. of
Treat
|
Fold Change | Log2FC | Rank | P-value | Corrected _P |
Promoter _T(co)F |
SE_T(co)F | TE_T(co)F |
|---|
| T(co)F | Pathway Name | Source | Gene Number |
|---|---|---|---|
| MITF | SUMOylation of transcription factors | Reactome | 14 |
| MITF | Hs_RANKL-RANK_(Receptor_activator_of_NFKB_(ligand))_Signaling_Pathway_WP2018_90016 | WikiPathways | 26 |
| MITF | Signaling mediated by p38-alpha and p38-beta | PID | 35 |
| MITF | Hs_Neural_Crest_Differentiation_WP2064_79263 | WikiPathways | 40 |
| MITF | Hs_Kit_receptor_signaling_pathway_WP304_78799 | WikiPathways | 46 |
| MITF | IL6-mediated signaling events | PID | 48 |
| MITF | Signaling events mediated by Stem cell factor receptor (c-Kit) | PID | 53 |
| MITF | Regulation of retinoblastoma protein | PID | 67 |
| MITF | Melanoma | KEGG | 69 |
| MITF | Regulation of nuclear beta catenin signaling and target gene transcription | PID | 80 |
| MITF | RANKL | NetPath | 84 |
| MITF | Melanogenesis | KEGG | 100 |
| MITF | KitReceptor | NetPath | 104 |
| MITF | Pathways in cancer | KEGG | 321 |