T(co)F Overview
T(co)F: ETV6
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Tryptophan cluster factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: U251
Tissue Type: Central_nervous_system
Biosample Type: Cell line
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE75003
Platform: GPL570
Pubmed ID: 27426982

ETV6- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of ETV6
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of ETV6
Upstream Pathway Annotation of ETV6
T(co)F Pathway Name Source Gene Number
ETV6 MAPK signaling pathway - fly KEGG 16
ETV6 ERK cascade ( FGF8 signaling (Mouse) ) INOH 17
ETV6 ERK cascade ( FGF8 signaling (Xenopus) ) INOH 17
ETV6 FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) ) INOH 18
ETV6 FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) ) INOH 20
ETV6 Dorso-ventral axis formation KEGG 25
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of ETV6
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines