T(co)F Overview
T(co)F: TCP1
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: ENCODE_TF
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR301SWM
Platform: -
Pubmed ID: 22955616

TCP1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of TCP1
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of TCP1
Upstream Pathway Annotation of TCP1
T(co)F Pathway Name Source Gene Number
TCP1 Folding of actin by CCT/TriC Reactome 10
TCP1 BBSome-mediated cargo-targeting to cilium Reactome 23
TCP1 Formation of tubulin folding intermediates by CCT/TriC Reactome 26
TCP1 Prefoldin mediated transfer of substrate to CCT/TriC Reactome 28
TCP1 Association of TriC/CCT with target proteins during biosynthesis Reactome 39
TCP1 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Reactome 42
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of TCP1
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines