| T(co)F: | NR4A1 |
| Species: | Homo sapiens |
| Knock-Method: | CRISPRi |
| T(co)F Class: | Nuclear receptors with C4 zinc fingers |
| T(co)F Superclass: | Zinc-coordinating DNA-binding domains |
| Biosample Name: | K562 |
| Tissue Type: | Haematopoietic_and_lymphoid_tissue |
| Biosample Type: | Cell line |
| # of Control: | 2 | # of Treat: | 2 |
| Data Source: | ENCODE |
| Profile ID: | ENCSR357LVC |
| Platform: | - |
| Pubmed ID: | 22955616 |
#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines
| Target Gene | T(co)F | Mean
Expr. of
Control
|
Mean
Expr. of
Treat
|
Fold Change | Log2FC | Rank | P-value | Corrected _P |
Promoter _T(co)F |
SE_T(co)F | TE_T(co)F |
|---|
| T(co)F | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NR4A1 | AKT phosphorylates targets in the nucleus | Reactome | 9 |
| NR4A1 | Constitutive Signaling by AKT1 E17K in Cancer | Reactome | 25 |
| NR4A1 | RXR and RAR heterodimerization with other nuclear receptor | PID | 26 |
| NR4A1 | Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017 | WikiPathways | 41 |
| NR4A1 | Nuclear Receptor transcription pathway | Reactome | 51 |
| NR4A1 | Role of Calcineurin-dependent NFAT signaling in lymphocytes | PID | 54 |
| NR4A1 | Hs_MAPK_Signaling_Pathway_WP382_79951 | WikiPathways | 58 |
| NR4A1 | Glucocorticoid receptor regulatory network | PID | 85 |
| NR4A1 | TCR | NetPath | 261 |
| NR4A1 | MAPK signaling pathway | KEGG | 264 |