T(co)F Overview
T(co)F: ATF3
Species: Homo sapiens
Knock-Method: CRISPRi
T(co)F Class: Basic leucine zipper factors (bZIP)
T(co)F Superclass: Basic domains
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR123IMQ
Platform: -
Pubmed ID: 22955616

ATF3- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of ATF3
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of ATF3
Upstream Pathway Annotation of ATF3
T(co)F Pathway Name Source Gene Number
ATF3 ATF4 activates genes Reactome 25
ATF3 ID NetPath 38
ATF3 ATF-2 transcription factor network PID 59
ATF3 AP-1 transcription factor network PID 71
ATF3 Regulation of nuclear SMAD2/3 signaling PID 82
ATF3 Apoptosis signaling pathway PANTHER 104
ATF3 Direct p53 effectors PID 141
ATF3 TGF_beta_Receptor NetPath 220
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of ATF3
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines