T(co)F Overview
T(co)F: SETDB1
Species: Homo sapiens
Knock-Method: CRISPRi
T(co)F Class: Others
T(co)F Superclass: ENCODE_TF
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 3
Data Source: ENCODE
Profile ID: ENCSR819PCU
Platform: -
Pubmed ID: 22955616

SETDB1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of SETDB1
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of SETDB1
Upstream Pathway Annotation of SETDB1
T(co)F Pathway Name Source Gene Number
SETDB1 Noncanonical Wnt signaling pathway PID 33
SETDB1 Lysine degradation KEGG 44
SETDB1 PKMTs methylate histone lysines Reactome 64
SETDB1 Wnt NetPath 118
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of SETDB1
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines