T(co)F Overview
T(co)F: GATA2
Species: Homo sapiens
Knock-Method: CRISPRi
T(co)F Class: Other C4 zinc finger-type factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR557BMX
Platform: -
Pubmed ID: 22955616

GATA2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of GATA2
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of GATA2
Upstream Pathway Annotation of GATA2
T(co)F Pathway Name Source Gene Number
GATA2 Hs_Apoptosis_WP254_88977 WikiPathways 31
GATA2 Regulation of Androgen receptor activity PID 54
GATA2 Signaling events mediated by HDAC Class II PID 58
GATA2 HIF-1-alpha transcription factor network PID 67
GATA2 AP-1 transcription factor network PID 71
GATA2 IL3 NetPath 84
GATA2 Signaling events mediated by HDAC Class I PID 89
GATA2 Factors involved in megakaryocyte development and platelet production Reactome 111
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of GATA2
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines