T(co)F Overview
T(co)F: POLR2G
Species: Homo sapiens
Knock-Method: CRISPRedit
T(co)F Class: Others
T(co)F Superclass: ENCODE_TF
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR580TGX
Platform: -
Pubmed ID: -

POLR2G- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of POLR2G
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of POLR2G
Upstream Pathway Annotation of POLR2G
T(co)F Pathway Name Source Gene Number
POLR2G Signaling by FGFR2 IIIa TM Reactome 19
POLR2G Abortive elongation of HIV-1 transcript in the absence of Tat Reactome 23
POLR2G MicroRNA (miRNA) biogenesis Reactome 23
POLR2G FGFR2 alternative splicing Reactome 27
POLR2G RNA Pol II CTD phosphorylation and interaction with CE Reactome 27
POLR2G Transcriptional regulation of pluripotent stem cells Reactome 28
POLR2G mRNA Capping Reactome 29
POLR2G PIWI-interacting RNA (piRNA) biogenesis Reactome 29
POLR2G Pausing and recovery of Tat-mediated HIV elongation Reactome 30
POLR2G Tat-mediated HIV elongation arrest and recovery Reactome 30
POLR2G Elongation arrest and recovery Reactome 32
POLR2G HIV elongation arrest and recovery Reactome 32
POLR2G Pausing and recovery of HIV elongation Reactome 32
POLR2G Formation of the Early Elongation Complex Reactome 33
POLR2G Formation of the HIV-1 Early Elongation Complex Reactome 33
POLR2G Processing of Capped Intron-Containing Pre-mRNA Reactome 37
POLR2G Tat-mediated elongation of the HIV-1 transcript Reactome 40
POLR2G Formation of HIV-1 elongation complex containing HIV-1 Tat Reactome 42
POLR2G RNA Polymerase II Transcription Elongation Reactome 42
POLR2G Viral Messenger RNA Synthesis Reactome 43
POLR2G Formation of HIV elongation complex in the absence of HIV Tat Reactome 44
POLR2G Formation of RNA Pol II elongation complex Reactome 44
POLR2G HIV Transcription Initiation Reactome 44
POLR2G RNA Polymerase II HIV Promoter Escape Reactome 44
POLR2G RNA Polymerase II Promoter Escape Reactome 44
POLR2G RNA Polymerase II Transcription Initiation And Promoter Clearance Reactome 44
POLR2G RNA Polymerase II Transcription Initiation Reactome 44
POLR2G RNA Polymerase II Transcription Pre-Initiation And Promoter Opening Reactome 44
POLR2G Transcription-Coupled Nucleotide Excision Repair (TC-NER) Reactome 44
POLR2G Transcription of the HIV genome Reactome 44
POLR2G U12 Dependent Splicing Reactome 50
POLR2G Formation of TC-NER Pre-Incision Complex Reactome 53
POLR2G TP53 Regulates Transcription of DNA Repair Genes Reactome 61
POLR2G Gap-filling DNA repair synthesis and ligation in TC-NER Reactome 62
POLR2G Dual incision in TC-NER Reactome 63
POLR2G RNA Polymerase II Pre-transcription Events Reactome 64
POLR2G RNA polymerase II transcribes snRNA genes Reactome 70
POLR2G Pyrimidine metabolism KEGG 99
POLR2G Transcriptional regulation by small RNAs Reactome 104
POLR2G Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome 120
POLR2G pre-mRNA splicing Reactome 135
POLR2G Purine metabolism KEGG 159
POLR2G Huntington's disease KEGG 182
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of POLR2G
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines