T(co)F Overview
T(co)F: GATA6
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Other C4 zinc finger-type factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: HT29
Tissue Type: Colon
Biosample Type: Cell line
# of Control: 1
# of Treat: 1
Data Source: GEO
Profile ID: GSE62316
Platform: GPL16686
Pubmed ID: 26387746

GATA6- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of GATA6
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of GATA6
Upstream Pathway Annotation of GATA6
T(co)F Pathway Name Source Gene Number
GATA6 POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation Reactome 10
GATA6 Surfactant metabolism Reactome 30
GATA6 Notch-mediated HES/HEY network PID 48
GATA6 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways 62
GATA6 Factors involved in megakaryocyte development and platelet production Reactome 111
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of GATA6
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines