T(co)F Overview
T(co)F: EGR2
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: C2H2 zinc finger factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: SK-N-MC
Tissue Type: Neuroepithelium
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: GEO
Profile ID: GSE62090
Platform: GPL19264
Pubmed ID: 26214589

EGR2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of EGR2
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of EGR2
Upstream Pathway Annotation of EGR2
T(co)F Pathway Name Source Gene Number
EGR2 Hs_Fatty_Acid_Beta_Oxidation_WP143_79783 WikiPathways 14
EGR2 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID 50
EGR2 Validated transcriptional targets of TAp63 isoforms PID 54
EGR2 IL4-mediated signaling events PID 66
EGR2 Transcriptional regulation of white adipocyte differentiation Reactome 79
EGR2 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome 120
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of EGR2
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines