T(co)F Overview
T(co)F: NFYB
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Heteromeric CCAAT-binding factors
T(co)F Superclass: Other all-alpha-helical DNA-binding domains
Biosample Name: U2OS ER-HA-E2F1
Tissue Type: Bone_marrow
Biosample Type: Cell line
# of Control: 18
# of Treat: 18
Data Source: GEO
Profile ID: GSE61272
Platform: GPL571
Pubmed ID: 26039627

NFYB- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of NFYB
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of NFYB
Upstream Pathway Annotation of NFYB
T(co)F Pathway Name Source Gene Number
NFYB ATF6-alpha activates chaperone genes Reactome 10
NFYB ATF4 activates genes Reactome 25
NFYB Activation of gene expression by SREBF (SREBP) Reactome 42
NFYB Validated targets of C-MYC transcriptional repression PID 63
NFYB Antigen processing and presentation KEGG 75
NFYB PPARA activates gene expression Reactome 113
NFYB Direct p53 effectors PID 141
NFYB TGF_beta_Receptor NetPath 220
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of NFYB
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines