T(co)F Overview
T(co)F: PGR
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Nuclear receptors with C4 zinc fingers
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: Endometrial stromal cells
Tissue Type: Uterus
Biosample Type: Primary cell
# of Control: 2
# of Treat: 2
Data Source: GEO
Profile ID: GSE48853
Platform: GPL571
Pubmed ID: 25875046

PGR- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of PGR
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of PGR
Upstream Pathway Annotation of PGR
T(co)F Pathway Name Source Gene Number
PGR Nuclear signaling by ERBB4 Reactome 25
PGR Cellular roles of Anthrax toxin PID 25
PGR Nuclear Receptor transcription pathway Reactome 51
PGR Validated nuclear estrogen receptor alpha network PID 65
PGR Progesterone-mediated oocyte maturation KEGG 84
PGR Oocyte meiosis KEGG 110
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of PGR
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines